Noninvasive approach to indicate risk factors of nonalcoholic steatohepatitis overlapping autoimmune hepatitis based on peripheral lymphocyte pattern
ConclusionsThe decreased frequency of peripheral CD8+ PD1+ T cells is an independent risk factor of NASH overlapping with AIH in the present cohort. Our findings will facilitate development of a new noninvasive FCM method for indicating risk factors of NASH, including autoimmunity. (Source: Journal of Gastroenterology)
Source: Journal of Gastroenterology - September 14, 2023 Category: Gastroenterology Source Type: research
Current status and issues in genomic analysis using EUS-FNA/FNB specimens in hepatobiliary –pancreatic cancers
AbstractComprehensive genomic profiling based on next-generation sequencing has recently been used to provide precision medicine for various advanced cancers. Endoscopic ultrasound (EUS)-guided fine-needle aspiration (EUS-FNA) and EUS-guided fine-needle biopsy (EUS-FNB) play essential roles in the diagnosis of abdominal masses, mainly pancreatic cancers. In recent years, CGP analysis using EUS-FNA/FNB specimens for hepatobiliary –pancreatic cancers has increased; however, the success rate of CGP analysis is not clinically satisfactory, and many issues need to be resolved to improve the success rate of CGP analysis. In th...
Source: Journal of Gastroenterology - September 12, 2023 Category: Gastroenterology Source Type: research
Correction: Partial splenic embolization combined with endoscopic therapies and vasoconstrictive drugs reduces rebleeding in cirrhosis patients with acute variceal bleeding and hypersplenism: a multicenter randomized controlled trial
(Source: Journal of Gastroenterology)
Source: Journal of Gastroenterology - September 12, 2023 Category: Gastroenterology Source Type: research
Current status and issues in genomic analysis using EUS-FNA/FNB specimens in hepatobiliary –pancreatic cancers
AbstractComprehensive genomic profiling based on next-generation sequencing has recently been used to provide precision medicine for various advanced cancers. Endoscopic ultrasound (EUS)-guided fine-needle aspiration (EUS-FNA) and EUS-guided fine-needle biopsy (EUS-FNB) play essential roles in the diagnosis of abdominal masses, mainly pancreatic cancers. In recent years, CGP analysis using EUS-FNA/FNB specimens for hepatobiliary –pancreatic cancers has increased; however, the success rate of CGP analysis is not clinically satisfactory, and many issues need to be resolved to improve the success rate of CGP analysis. In th...
Source: Journal of Gastroenterology - September 12, 2023 Category: Gastroenterology Source Type: research
Correction: Partial splenic embolization combined with endoscopic therapies and vasoconstrictive drugs reduces rebleeding in cirrhosis patients with acute variceal bleeding and hypersplenism: a multicenter randomized controlled trial
(Source: Journal of Gastroenterology)
Source: Journal of Gastroenterology - September 12, 2023 Category: Gastroenterology Source Type: research
Incidence and risk factors for venous thromboembolism in the Cancer-VTE Registry pancreatic cancer subcohort
ConclusionsThe cumulative incidence of composite VTE during cancer treatment was higher in pancreatic cancer than in other cancer types. Some risk factors for VTE prevalence at cancer diagnosis were identified. Although VTE prevalence at cancer diagnosis did not predict the subsequent 1-year incidence of composite VTE, it was a significant predictor of other events such as all-cause death in pancreatic cancer patients.Trial registrationUMIN Clinical Trials Registry; UMIN000024942 (Source: Journal of Gastroenterology)
Source: Journal of Gastroenterology - September 7, 2023 Category: Gastroenterology Source Type: research
Global, regional, and national burden of liver cancer due to non-alcoholic steatohepatitis, 1990 –2019: a decomposition and age–period–cohort analysis
ConclusionThe global absolute deaths and ASDR of NALC have witnessed a rise in the past decade, with populations exhibiting considerable disparities based on sex, age, and region. Population growth, aging, and metabolism-related factors were the main factors behind the increase in global NALC deaths. (Source: Journal of Gastroenterology)
Source: Journal of Gastroenterology - September 4, 2023 Category: Gastroenterology Source Type: research
Analysis of the development of gastric cancer after resecting colorectal lesions using large-scale health insurance claims data
ConclusionsUsing large-scale data, risk factors for GC, including colorecal lesions ≥ 2 cm after C-ER could be investigated. (Source: Journal of Gastroenterology)
Source: Journal of Gastroenterology - August 30, 2023 Category: Gastroenterology Source Type: research
Application of polyglycolic acid sheets and basic fibroblast growth factor to prevent esophageal stricture after endoscopic submucosal dissection in pigs
ConclusionsStenosis after esophageal ESD is related to fibrosis in the acute phase. Administration of PGA and bFGF suppresses myofibroblast activation in the acute phase, thereby preventing esophageal constriction in pigs. (Source: Journal of Gastroenterology)
Source: Journal of Gastroenterology - August 27, 2023 Category: Gastroenterology Source Type: research
