Prediction of outcomes in patients with metabolic dysfunction-associated steatotic liver disease based on initial measurements and subsequent changes in magnetic resonance elastography
ConclusionsBoth initial LSM and ΔLSM can predict liver-related events in patients with MASLD, even for low initial LSM. This integrated assessment can allow more detailed risk stratification compared with single LSM assessments and identify high-risk patients with MASLD among those previously considered as low risk. (Source: Journal of Gastroenterology)
Source: Journal of Gastroenterology - October 16, 2023 Category: Gastroenterology Source Type: research
A survey questionnaire evaluating physical activity patterns and determinants in patients with chronic liver disease
ConclusionsPatients with CLD are insufficiently active and need physical activity interventions, especially regarding walking. (Source: Journal of Gastroenterology)
Source: Journal of Gastroenterology - October 16, 2023 Category: Gastroenterology Source Type: research
Clinical outcome after cessation of nucleos(t)ide analog treatment in chronic hepatitis B patients who achieved HBsAg seroclearance
ConclusionsPatients receiving NA treatment who achieved HBsAg seroclearance as determined by HBsAg QT assay rarely experienced virological or clinical relapse after the cessation of treatment. (Source: Journal of Gastroenterology)
Source: Journal of Gastroenterology - October 14, 2023 Category: Gastroenterology Source Type: research
Posttreatment liver function, but not baseline liver function stratifies patient survival after direct-acting antiviral treatment in decompensated cirrhosis with hepatitis C virus
ConclusionsThe prognosis of decompensated cirrhotic patients receiving DAA was stratified by liver function at 12 weeks after the EOT, not by baseline liver function. (Source: Journal of Gastroenterology)
Source: Journal of Gastroenterology - October 13, 2023 Category: Gastroenterology Source Type: research
Real-world efficacy and safety of advanced therapies in hospitalized patients with ulcerative colitis
ConclusionMost first-use ATs were effective for patients with ASUC, while second-use ATs might have had limited benefits in inducing CR. These findings may contribute to considerations for the management of hospitalized patients. (Source: Journal of Gastroenterology)
Source: Journal of Gastroenterology - October 13, 2023 Category: Gastroenterology Source Type: research
Posttreatment liver function, but not baseline liver function stratifies patient survival after direct-acting antiviral treatment in decompensated cirrhosis with hepatitis C virus
ConclusionsThe prognosis of decompensated cirrhotic patients receiving DAA was stratified by liver function at 12 weeks after the EOT, not by baseline liver function. (Source: Journal of Gastroenterology)
Source: Journal of Gastroenterology - October 13, 2023 Category: Gastroenterology Source Type: research
Real-world efficacy and safety of advanced therapies in hospitalized patients with ulcerative colitis
ConclusionMost first-use ATs were effective for patients with ASUC, while second-use ATs might have had limited benefits in inducing CR. These findings may contribute to considerations for the management of hospitalized patients. (Source: Journal of Gastroenterology)
Source: Journal of Gastroenterology - October 13, 2023 Category: Gastroenterology Source Type: research
New chemiluminescent enzyme immunoassay for quantitative measurement of Mac-2 binding protein glycosylation isomer in chronic liver disease
ConclusionCompared with qualitative methods, the M2BPGi quantitative measurement system could provide a numerical value unaffected by interpretation bias, and measurements are more precise at high M2BPGi levels. (Source: Journal of Gastroenterology)
Source: Journal of Gastroenterology - October 8, 2023 Category: Gastroenterology Source Type: research
Comparison of vonoprazan-based with rabeprazole-based dual therapy for treatment-naive patients of Helicobacter pylori infection: a prospective, multi-center, randomized controlled study
ConclusionsThe 10-day VA dual therapy was non-inferior to the 14-day RA dual therapy forH. pylori treatment-naive patients, which should be given priority in the first-line treatment. The application of vonoprazan reduced treatment course and antibiotic use. Patients ’ adherence was crucial for the success of eradication. (Source: Journal of Gastroenterology)
Source: Journal of Gastroenterology - October 1, 2023 Category: Gastroenterology Source Type: research
Correction: Evidence-based clinical practice guidelines for irritable bowel syndrome 2020
(Source: Journal of Gastroenterology)
Source: Journal of Gastroenterology - September 26, 2023 Category: Gastroenterology Source Type: research
Cost-effectiveness analysis of nivolumab plus chemotherapy vs chemotherapy for patients with unresectable advanced or metastatic HER2-negative gastric or gastroesophageal junction or esophageal adenocarcinoma in Japan
ConclusionsApplying the Japanese cancer threshold of USD75,000 –150,000/QALY, NIVO + Chemo was not cost-effective for patients with advanced or metastatic HER2-negative GC/GEJC/EAC in Japan from the perspective of healthcare payer. (Source: Journal of Gastroenterology)
Source: Journal of Gastroenterology - September 19, 2023 Category: Gastroenterology Source Type: research
