JAIDS Journal of Acquired Immune Deficiency Syndromes 
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This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.HIV Risk Factors and Risk Perception Among Adolescent Girls and Young Women: Results From a Population-Based Survey in Western Kenya, 2018
Conclusion:
Gaps in perceived HIV risk persist among AGYW in Kenya. High access to HIV testing and prevention services in this population highlights platforms through which AGYW may be reached with improved risk counseling, and to increase uptake of HIV prevention strategies. (Source: JAIDS Journal of Acquired Immune Deficiency Syndromes)
Source: JAIDS Journal of Acquired Immune Deficiency Syndromes - August 24, 2022 Category: Infectious Diseases Tags: Epidemiology Source Type: research
HIV Incidence in Botswana Rural Communities With High Antiretroviral Treatment Coverage: Results From the Botswana Combination Prevention Project, 2013–2017
We report rates and characteristics of incident HIV infections.
Methods:
The Botswana Combination Prevention Project was a community-randomized controlled trial conducted in 30 rural/periurban Botswana communities from 2013 to 2017. Home-based and mobile HIV-testing campaigns were conducted in 15 intervention communities, with 39% of participants testing at least twice. We assessed the HIV incidence rate [IR; number of new HIV infections per 100 person-years (py) at risk] among repeat testers and risk factors with a Cox proportional hazards regression model.
Results:
During 27,517 py, 195 (women: 79%) of 18,5...
Source: JAIDS Journal of Acquired Immune Deficiency Syndromes - August 24, 2022 Category: Infectious Diseases Tags: Epidemiology Source Type: research
Sexually Transmitted Infections Among Men and Transgender Women Using HIV Pre-exposure Prophylaxis in a Large Integrated Health System—A Cohort Study
We examined risk and factors associated with STIs in a cohort of PrEP users in an integrated health system in the United States.
Setting:
The Kaiser Permanente Southern California is a large integrated health system that provides comprehensive medical services to approximately 4.7 million demographically diverse members.
Methods:
We identified men and transgender women initiating PrEP between January 1, 2014, and June 1, 2018, and followed through December 31, 2018. Demographic and clinical factors potentially associated with the risk of bacterial STIs during PrEP use were evaluated using Poisson regression m...
Source: JAIDS Journal of Acquired Immune Deficiency Syndromes - August 24, 2022 Category: Infectious Diseases Tags: Epidemiology Source Type: research
Effect of HIV Serostatus on ICU Admission and Mortality Among Hospitalized Patients With Coronavirus Disease 2019 (COVID-19)
No abstract available (Source: JAIDS Journal of Acquired Immune Deficiency Syndromes)
Source: JAIDS Journal of Acquired Immune Deficiency Syndromes - July 20, 2022 Category: Infectious Diseases Tags: Letters to the Editor Source Type: research
Association of PTSD With Longitudinal COVID-19 Burden in a Mixed-Serostatus Cohort of Men and Women: Weathering the Storm
Conclusions:
This study builds on emerging literature demonstrating the impact of mental health on the burden and disruption associated with the COVID-19 pandemic, providing context specific to PWH. The ongoing pandemic requires structural and social interventions to decrease disruption to resources and health resource needs among these vulnerable populations. (Source: JAIDS Journal of Acquired Immune Deficiency Syndromes)
Source: JAIDS Journal of Acquired Immune Deficiency Syndromes - July 20, 2022 Category: Infectious Diseases Tags: Clinical Science Source Type: research
Brief Report: Validation of the D:A:D Chronic Kidney Disease Risk Score Incorporating Proteinuria in People Living With HIV in Harare, Zimbabwe
Conclusion:
A modified version of the D:A:D CKD risk score performed well in predicting CKD events among this sub-Saharan African cohort of people living with HIV. Inclusion of proteinuria into the risk score model significantly improved predictability. (Source: JAIDS Journal of Acquired Immune Deficiency Syndromes)
Source: JAIDS Journal of Acquired Immune Deficiency Syndromes - July 20, 2022 Category: Infectious Diseases Tags: Clinical Science Source Type: research
Modeling the Impact of HIV-1 Nucleic Acid Testing Among Symptomatic Adult Outpatients in Kenya
Conclusion:
Our study suggests that leveraging new technologies to identify acute HIV infection among symptomatic outpatients is superior to scaled-up PITC in this population, resulting in>95% knowledge of HIV status, and would reduce new HIV infections in Kenya. (Source: JAIDS Journal of Acquired Immune Deficiency Syndromes)
Source: JAIDS Journal of Acquired Immune Deficiency Syndromes - July 20, 2022 Category: Infectious Diseases Tags: Implementation Science Source Type: research
Prescribe to Save Lives: Improving Buprenorphine Prescribing Among HIV Clinicians
Conclusions:
Although the PtSL intervention resulted in increases in buprenorphine training and prescriber certification, there was no meaningful increase in buprenorphine prescribing. Engaging and teaching HIV clinicians about overdose and naloxone rescue may facilitate training in buprenorphine prescribing but will not result in more treatment with buprenorphine without additional interventions. (Source: JAIDS Journal of Acquired Immune Deficiency Syndromes)
Source: JAIDS Journal of Acquired Immune Deficiency Syndromes - July 20, 2022 Category: Infectious Diseases Tags: Implementation Science Source Type: research
Direct and Indirect Effects of a Project ECHO Longitudinal Clinical Tele-Mentoring Program on Viral Suppression for Persons With HIV: A Population-Based Analysis
Background:
Project Extension for Community Health Outcomes (ECHO) aims to connect community providers to academic specialists, deliver longitudinal clinical mentorship and case consultations, plus encourage dissemination of knowledge and resources. The impact on outcomes for persons with HIV (PWH) is uncertain.
Setting:
PWH in Washington and Oregon outside of the Seattle and Portland metro areas, January 2011 to March 2018.
Methods:
Using viral load (VL) surveillance data, we assessed difference in the percentage of PWH who were virally suppressed among PWH whose providers participated versus did not par...
Source: JAIDS Journal of Acquired Immune Deficiency Syndromes - July 20, 2022 Category: Infectious Diseases Tags: Implementation Science Source Type: research
A Demedicalized Model to Provide PrEP in a Sexual Health Clinic
Background:
Sexual health clinics (SHCs) serve large numbers of patients who might benefit from preexposure prophylaxis (PrEP). Integrating longitudinal PrEP care into SHCs can overburden clinics. We implemented an SHC PrEP program that task shifted most PrEP operations to nonmedical staff, disease intervention specialists (DIS).
Methods:
We conducted a retrospective cohort analysis of PrEP patients in an SHC in Seattle, WA, from 2014 to 2020 to assess the number of patients served and factors associated with PrEP discontinuation. Clinicians provide same-day PrEP prescriptions, whereas DIS coordinate the program...
Source: JAIDS Journal of Acquired Immune Deficiency Syndromes - July 20, 2022 Category: Infectious Diseases Tags: Implementation Science Source Type: research
Targeted Implementation of HIV Self-Testing Increases Testing Uptake Among Partners of Index Persons Known to Have HIV in Kenya
Background:
Partners of persons living with HIV (PLHIV) are at a high risk of HIV acquisition, particularly if PLHIV are newly diagnosed or not virally suppressed. A focused partner HIV testing strategy could stimulate efficient identification of persons for pre-exposure prophylaxis (PrEP) or antiretroviral therapy (ART) programs.
Methods:
We sequentially implemented 2 partner testing strategies at 2 Kenyan HIV clinics: (1) an invitation for clinic-based testing and (2) HIV self-testing (HIVST) kits distribution to index PLHIV. For each testing strategy, we enrolled approximately 150 consecutive index PLHIV with...
Source: JAIDS Journal of Acquired Immune Deficiency Syndromes - July 20, 2022 Category: Infectious Diseases Tags: Implementation Science Source Type: research
Brief Report: Pediatric Saliva-Based HIV Testing: Health care Worker and Caregiver Acceptability
Conclusions:
SBT was generally acceptable to HCWs and caregivers and is a promising strategy to expand testing coverage. (Source: JAIDS Journal of Acquired Immune Deficiency Syndromes)
Source: JAIDS Journal of Acquired Immune Deficiency Syndromes - July 20, 2022 Category: Infectious Diseases Tags: Implementation Science Source Type: research
Randomized Controlled Trial of Healthy Divas: A Gender-Affirming, Peer-Delivered Intervention to Improve HIV Care Engagement Among Transgender Women Living With HIV
Conclusions:
This trial demonstrates the short-term efficacy of an urgently needed behavioral intervention to improve engagement in HIV care among transgender women living with HIV; ongoing intervention may be needed to maintain positive impact over time.
Trial Registration:
Clinicaltrials.gov identifier: NCT03081559. (Source: JAIDS Journal of Acquired Immune Deficiency Syndromes)
Source: JAIDS Journal of Acquired Immune Deficiency Syndromes - July 20, 2022 Category: Infectious Diseases Tags: Prevention Research Source Type: research
Brief Report: Previous Preexposure Prophylaxis Use Among Men Who Have Sex With Men Newly Diagnosed With HIV Infection in King County, WA
Background:
Preexposure prophylaxis (PrEP) discontinuations are common and are associated with subsequent HIV acquisition. The population-level impact of PrEP discontinuations is unknown.
Methods:
Public health staff routinely asked men who have sex with men (MSM) with newly diagnosed HIV infection about their history of PrEP use as part of partner notification interviews in King County, WA, from 2013 to 2021. We assessed trends in the proportion of MSM who ever took PrEP and described reasons for PrEP discontinuation.
Results:
A total of 1098 MSM were newly diagnosed with HIV during the study period; of ...
Source: JAIDS Journal of Acquired Immune Deficiency Syndromes - July 20, 2022 Category: Infectious Diseases Tags: Prevention Research Source Type: research
Understanding Diagnostic Delays for Kaposi Sarcoma in Kenya: A Qualitative Study
Conclusions:
Lack of KS awareness among patients and providers, stigma surrounding diagnoses, and health system referral delays were barriers in reaching KS diagnosis. Improved public health campaigns, increased availability of biopsy and pathology facilities, and health provider training about KS are needed to improve early diagnosis of KS. (Source: JAIDS Journal of Acquired Immune Deficiency Syndromes)
Source: JAIDS Journal of Acquired Immune Deficiency Syndromes - July 20, 2022 Category: Infectious Diseases Tags: Epidemiology Source Type: research
