Prediction of lymph node metastasis in operable cervical cancer using clinical parameters and deep learning with MRI data: a multicentre study
ConclusionThe proposed hybrid model could be used as a personalised non-invasive tool, which is helpful for predicting LNM in operable cervical cancer. The score of the hybrid model could also reflect the DFS of operable cervical cancer.Critical relevance statementLymph node metastasis is an important factor affecting the prognosis of cervical cancer. Preoperative prediction of lymph node status is helpful to make treatment decisions, improve prognosis, and prolong survival time.Key points• The MRI-based deep-learning model can predict the LNM in operable cervical cancer.• The hybrid model has the highest diagnostic ef...
Source: Insights into Imaging - February 27, 2024 Category: Radiology Source Type: research
The use of PET/MRI in radiotherapy
This article critically assesses the transformative role of PET/MRI in advancing precision radiotherapy, providing essential insights into improved radiation positioning, target delineation, efficacy evaluation, and patient surveillance in clinical radiology practice.Key points• The emergence of PET/MRI will be a key bridge for precise radiotherapy.• PET/MRI has unique advantages in the whole process of radiotherapy.• New tracers and nanoparticle probes will broaden the use of PET/MRI in radiation.• PET/MRI will be utilized more frequently for radiotherapy.Graphical Abstract (Source: Insights into Imaging)
Source: Insights into Imaging - February 27, 2024 Category: Radiology Source Type: research
Liver imaging and pregnancy: what to expect when your patient is expecting
AbstractLiver diseases in pregnancy can be specific to gestation or only coincidental. In the latter case, the diagnosis can be difficult. Rapid diagnosis of maternal-fetal emergencies and situations requiring specialized interventions are crucial to preserve the maternal liver and guarantee materno-fetal survival. While detailed questioning of the patient and a clinical examination are highly important, imaging is often essential to reach a diagnosis of these liver diseases and lesions. Three groups of liver diseases may be observed during pregnancy: (1) diseases related to pregnancy: intrahepatic cholestasis of pregnancy...
Source: Insights into Imaging - February 27, 2024 Category: Radiology Source Type: research
Deep learning model based on multi-lesion and time series CT images for predicting the benefits from anti-HER2 targeted therapy in stage IV gastric cancer
ConclusionThe Nomo-LDLM-2F score derived from multi-lesion and time series CT images holds promise for the effective readout of OS probability in patients with HER2-positive stage IV GC receiving anti-HER2 therapy.Critical relevance statementThe deep learning model using baseline and early follow-up CT images aims to predict OS in patients with stage IV gastric cancer receiving anti-HER2 targeted therapy. This model highlights the spatiotemporal heterogeneity of stage IV GC, assisting clinicians in the early evaluation of the efficacy of anti-HER2 therapy.Key points• Multi-lesion and time series model revealed the spatio...
Source: Insights into Imaging - February 27, 2024 Category: Radiology Source Type: research
Computed tomography-based body composition parameters can predict short-term prognosis in ulcerative colitis patients
ConclusionsThe predicting model constructed with CT-based body composition parameters is a potential non-invasive approach for short-term prognosis identification and risk stratification. Additionally, VAT density was an independent predictor for escalating therapeutic regimens in UC cohorts.Critical relevance statementThe CT images were used for evaluating body composition and risk stratification of ulcerative colitis patients, and a potential non-invasive prediction model was constructed to identify non-responders with conventional therapy for making therapeutic regimens timely and accurately.Key points• CT-based predi...
Source: Insights into Imaging - February 27, 2024 Category: Radiology Source Type: research
The value of periportal hyperintensity sign from gadobenate dimeglumine-enhanced hepatobiliary phase MRI for predicting clinical outcomes in patients with decompensated cirrhosis
ConclusionsPeriportal hyperintensity sign from Gd-BOPTA-enhanced HBP MRI is valuable for predicting clinical outcomes in patients with decompensated cirrhosis.Critical relevance statementPeriportal hyperintensity sign from gadobenate dimeglumine-enhanced hepatobiliary phase magnetic resonance imaging is a new noninvasive method to predict clinical outcomes in patients with decompensated cirrhosis.Key points• There was a significant difference in the frequency of periportal hyperintensity sign on HBP between compensated and decompensated cirrhotic patients.• Periportal hyperintensity sign on the hepatobiliary phase was ...
Source: Insights into Imaging - February 27, 2024 Category: Radiology Source Type: research
Review of strategies to reduce the contamination of the water environment by gadolinium-based contrast agents
AbstractGadolinium-based contrast agents (GBCA) are essential for diagnostic MRI examinations. GBCA are only used in small quantities on a per-patient basis; however, the acquisition of contrast-enhanced MRI examinations worldwide results in the use of many thousands of litres of GBCA per year. Data shows that these GBCA are present in sewage water, surface water, and drinking water in many regions of the world. Therefore, there is growing concern regarding the environmental impact of GBCA because of their ubiquitous presence in the aquatic environment. To address the problem of GBCA in the water system as a whole, collabo...
Source: Insights into Imaging - February 27, 2024 Category: Radiology Source Type: research
Coronary chronic total occlusion on coronary CT angiography: what radiologists should know?
AbstractCoronary chronic total occlusion (CTO) often occurs in patients with obstructive coronary artery disease, which remains one of the greatest challenges for interventional cardiologists. Coronary computed tomography angiography (CCTA) with its emerging post-processing techniques can provide a detailed assessment of CTO lesions before percutaneous coronary intervention (PCI), playing an important role in the clinical management of CTO PCI, from early diagnosis, pre-procedural outcome prediction, the crossing algorithm planning, intraprocedural guidance, and finally post-procedural assessment and follow-up. In addition...
Source: Insights into Imaging - February 27, 2024 Category: Radiology Source Type: research
CT and MRI radiomics of bone and soft-tissue sarcomas: an updated systematic review of reproducibility and validation strategies
ConclusionsCompared to papers published up to 2020, a clear improvement was noted with almost double publications reporting methodological aspects related to reproducibility and validation. Larger multicenter investigations including external clinical validation and the publication of databases in open-access repositories could further improve methodology and bring radiomics from a research area to the clinical stage.Critical relevance statementAn improvement in feature reproducibility and model validation strategies has been shown in this updated systematic review on radiomics of bone and soft-tissue sarcomas, highlightin...
Source: Insights into Imaging - February 27, 2024 Category: Radiology Source Type: research
Rotator cuff tear patterns: MRI appearance and its surgical relevance
AbstractA new perspective on rotator cuff anatomy has allowed a better understanding of the patterns of the different rotator cuff tears. It is essential for radiologists to be aware of these different patterns of tears and to understand how they might influence treatment and surgical approach. Our objective is to review the arthroscopy correlated magnetic resonance imaging appearance of the different types of rotator cuff tears based on current anatomical concepts.Critical relevance statement Knowledge of the characteristics of rotator cuff tears improves our communication with the surgeon and can also make it easier for ...
Source: Insights into Imaging - February 27, 2024 Category: Radiology Source Type: research
MRI-based synthetic CT for assessment of the bony elements of the sacroiliac joints in children
ConclusionsCT appears to be visually equivalent to CT for the assessment of pediatric sacroiliac joints. sCT may aid in visualizing sacroiliac joints compared to conventional MRI, with the benefit that no ionizing radiation is used, especially important in children.Critical relevance statementMRI-based synthetic CT, a new technique that generates CT-like images without ionizing radiation, appears to be visually equivalent to CT for assessment of normal pediatric sacroiliac joints and can potentially assess structural damage as it clearly depicts bony cortex.Key points• MRI-based sCT is a new image technique that can gene...
Source: Insights into Imaging - February 18, 2024 Category: Radiology Source Type: research
How AI should be used in radiology: assessing ambiguity and completeness of intended use statements of commercial AI products
ConclusionThe majority of IUSs of CE-marked AI-based medical devices lack substantial information and, in few cases, contradict the claims of the product.Critical relevance statementTo ensure correct usage and to avoid off-label use or foreseeable misuse of AI-based medical devices in radiology, manufacturers are encouraged to provide more comprehensive and less ambiguous intended use statements.Key points• Radiologists must know AI products’ intended use to avoid off-label use or misuse.• Ninety-five percent (n = 132/139) of the intended use statements analyzed were incomplete.• Nine percent (n = 13) of th...
Source: Insights into Imaging - February 16, 2024 Category: Radiology Source Type: research
Assessment of intestinal luminal stenosis and prediction of endoscopy passage in Crohn ’s disease patients using MRI
ConclusionsThe utilization of MRE signs for assessing the passage of an endoscope through the narrow segment revealed that the diameter of the upstream intestine emerged as an independent predictor of endoscopic passage. Before performing an endoscopy, MRE can aid in evaluating the passage of the endoscope.Critical relevance statementThis retrospective study explored the imaging features of MRE to evaluate intestinal stenosis in patients with Crohn ’s disease and determined that the diameter of the upstream intestine of the stenotic segment was an independent predictor in assessing endoscopic passage.Key points• Endosc...
Source: Insights into Imaging - February 16, 2024 Category: Radiology Source Type: research
Intravoxel incoherent motion diffusion-weighted imaging for predicting kidney allograft function decline: comparison with clinical parameters
ConclusionsDWI parameters were comparable to clinical parameters in predicting kidney allograft function decline. Integrating cortical D and fp into the clinical model with baseline eGFR and proteinuria may add prognostic value for long-term allograft function decline.Critical relevance statementOur findings suggested that cortical D and fp derived from IVIM-DWI increased the performance to predict long-term kidney allograft function decline. This preliminary study provided basis for the utility of multi-b DWI for managing patients with a kidney transplant.Key points• Both clinical and multi-b DWI parameters could predic...
Source: Insights into Imaging - February 16, 2024 Category: Radiology Source Type: research
Curation of myeloma observational study MALIMAR using XNAT: solving the challenges posed by real-world data
ConclusionsMALIMAR exemplifies the vital role that curation plays in machine learning studies that use real-world data. A research repository such as XNAT facilitates day-to-day management, ensures robustness and consistency and enhances the value of the final dataset. The types of process described here will be vital for future large-scale multi-institutional and multi-national imaging projects.Critical relevance statementThis article showcases innovative data curation methods using a state-of-the-art image repository platform; such tools will be vital for managing the large multi-institutional datasets required to train ...
Source: Insights into Imaging - February 16, 2024 Category: Radiology Source Type: research
