Intravoxel incoherent motion diffusion-weighted imaging for predicting kidney allograft function decline: comparison with clinical parameters

ConclusionsDWI parameters were comparable to clinical parameters in predicting kidney allograft function decline. Integrating cortical D and fp into the clinical model with baseline eGFR and proteinuria may add prognostic value for long-term allograft function decline.Critical relevance statementOur findings suggested that cortical D and fp derived from IVIM-DWI increased the performance to predict long-term kidney allograft function decline. This preliminary study provided basis for the utility of multi-b DWI for managing patients with a kidney transplant.Key points• Both clinical and multi-b DWI parameters could predict kidney allograft function decline.• The ability to predict kidney allograft function decline was similar between DWI and clinical parameters.• Cortical D and fp derived from IVIM-DWI increased the performance to predict long-term kidney allograft function decline.Graphical Abstract
Source: Insights into Imaging - Category: Radiology Source Type: research