CT and MRI radiomics of bone and soft-tissue sarcomas: an updated systematic review of reproducibility and validation strategies

ConclusionsCompared to papers published up to 2020, a clear improvement was noted with almost double publications reporting methodological aspects related to reproducibility and validation. Larger multicenter investigations including external clinical validation and the publication of databases in open-access repositories could further improve methodology and bring radiomics from a research area to the clinical stage.Critical relevance statementAn improvement in feature reproducibility and model validation strategies has been shown in this updated systematic review on radiomics of bone and soft-tissue sarcomas, highlighting efforts to enhance methodology and bring radiomics from a research area to the clinical stage.Key points• 2021–2023 radiomic studies on CT and MRI of musculoskeletal sarcomas were reviewed.• Feature reproducibility was assessed in more than half (59%) of the studies.• Model clinical validation was performed in 69% of the studies.• Internal (44%) and/or external (29%) test datasets were employed for clinical validation.Graphical Abstract
Source: Insights into Imaging - Category: Radiology Source Type: research