Evaluation of anticancer activity of Clerodendrum viscosum leaves against breast carcinoma
CONCLUSION: The above-combined results revealed the anticancer effect of CVLME, which may be due to the selective induction of ROS in breast carcinoma. (Source: Indian Journal of Pharmacology)
Source: Indian Journal of Pharmacology - November 24, 2021 Category: Drugs & Pharmacology Authors: Anil Khushalrao Shendge Tapasree Basu Nripendranath Mandal Source Type: research
Topical steroid containing combinations: Burden of adverse effects and why the recent regulatory action may not be enough
CONCLUSION: Nearly half of the cutaneous adverse effects were due to topical steroid combinations which are still widely available over the counter. (Source: Indian Journal of Pharmacology)
Source: Indian Journal of Pharmacology - November 24, 2021 Category: Drugs & Pharmacology Authors: Ratinder Jhaj Dinesh Prasad Asati Deepa Chaudhary Balakrishnan Sadasivam Source Type: research
Pentaglobin (immunoglobulin M-enriched immunoglobulin) as adjuvant therapy for premature and very low-birth-weight neonates with sepsis
CONCLUSION: Neonatal sepsis is more common in premature and VLBW newborns, and Pentaglobin® management of newborn nosocomial sepsis might be used in addition to other therapies. (Source: Indian Journal of Pharmacology)
Source: Indian Journal of Pharmacology - November 24, 2021 Category: Drugs & Pharmacology Authors: Kawthar F Nassir Yasir Ibrahim AL-Saddi Hassan M Abbas Qutaiba Ahmed Al Khames Aga Luma Ahmed Al Khames Aga Ameer A Oudah Source Type: research
A randomized comparative study of methylcobalamin, methylcobalamin plus pregabalin and methylcobalamin plus duloxetine in patients of painful diabetic neuropathy
CONCLUSIONS: Group C is more efficacious when compared to Groups A and B while Group B is safer. (Source: Indian Journal of Pharmacology)
Source: Indian Journal of Pharmacology - November 24, 2021 Category: Drugs & Pharmacology Authors: Chetna Sharma Inderpal Kaur Harpreet Singh Inderpal Singh Grover Jatinder Singh Source Type: research
Impact of Organization for Economic Co-Operation and Development (OECD) principles of Good Laboratory practices (GLP) in India
Ekta Kapoor, Neeraj Sharma, Rupa Joshi, Bikash MedhiIndian Journal of Pharmacology 2021 53(5):353-357 (Source: Indian Journal of Pharmacology)
Source: Indian Journal of Pharmacology - November 24, 2021 Category: Drugs & Pharmacology Authors: Ekta Kapoor Neeraj Sharma Rupa Joshi Bikash Medhi Source Type: research
A successful protocol for desensitization to iron salts
Kadriye Terzioglu, Kürşat EpöztürkIndian Journal of Pharmacology 2021 53(4):332-333 (Source: Indian Journal of Pharmacology)
Source: Indian Journal of Pharmacology - August 18, 2021 Category: Drugs & Pharmacology Authors: Kadriye Terzioglu K ü r & #351;at Ep ö zt ü rk Source Type: research
Nilotinib-induced generalized keratosis pilaris: Report of a rare case
Priyanka Arun Kowe, Vaishali H W.hade, Sakshi S Malpani, Rajesh P SinghIndian Journal of Pharmacology 2021 53(4):330-331 (Source: Indian Journal of Pharmacology)
Source: Indian Journal of Pharmacology - August 18, 2021 Category: Drugs & Pharmacology Authors: Priyanka Arun Kowe Vaishali H Wankhade Sakshi S Malpani Rajesh P Singh Source Type: research
Apremilast induced tinnitus: An unreported side effect
Rajiv Ramesh Sule, Paras Choudhary, Tejaswini Sopanrao SalunkeIndian Journal of Pharmacology 2021 53(4):328-329 (Source: Indian Journal of Pharmacology)
Source: Indian Journal of Pharmacology - August 18, 2021 Category: Drugs & Pharmacology Authors: Rajiv Ramesh Sule Paras Choudhary Tejaswini Sopanrao Salunke Source Type: research
Rhino-orbital-cerebral-mucormycosis in COVID-19: A systematic review
Anusuya Bhattacharyya, Phulen Sarma, Dibya Jyoti Sharma, Karuna Kumar Das, Hardeep Kaur, Manisha Prajapat, Subodh Kumar, Seema Bansal, Ajay Prakash, Pramod Avti, Prasad Thota, Dibbanti Harikrishna Reddy, Bhaswati Sharma Gautam, Bikash MedhiIndian Journal of Pharmacology 2021 53(4):317-327
Since the onset of COVID-19 pandemic, parallel opportunistic infections have also been emerging as another disease spectrum. Among all these opportunistic infection, mucormycosis has become a matter of concern with its rapid increase of cases with rapid spread as compared to pre-COVID-19 era. Cases have been reported in post-COVID-19-rel...
Source: Indian Journal of Pharmacology - August 18, 2021 Category: Drugs & Pharmacology Authors: Anusuya Bhattacharyya Phulen Sarma Dibya Jyoti Sharma Karuna Kumar Das Hardeep Kaur Manisha Prajapat Subodh Kumar Seema Bansal Ajay Prakash Pramod Avti Prasad Thota Dibbanti Harikrishna Reddy Bhaswati Sharma Gautam Bikash Medhi Source Type: research
Update on geographical variation and distribution of SARS-nCoV-2: A systematic review
Manisha Prajapat, Vrishbhanu Handa, Phulen Sarma, Ajay Prakash, Hardeep Kaur, Saurabh Sharma, Anusuya Bhattacharyya, Subodh Kumar, Amit Raj Sharma, Pramod Avti, Bikash MedhiIndian Journal of Pharmacology 2021 53(4):310-316
Knowledge of a new mutant strain of SARS-coronavirus (CoV-2) is enormously essential to identify a targeted drug and for the development of the vaccine. In this article, we systematically reviewed the different mutation strains (variant of concern [VOC] and variant of interest [VOI]) which were found in different countries such as the UK, Singapore, China, Germany, Vietnam, Western Africa, Dublin, Irela...
Source: Indian Journal of Pharmacology - August 18, 2021 Category: Drugs & Pharmacology Authors: Manisha Prajapat Vrishbhanu Handa Phulen Sarma Ajay Prakash Hardeep Kaur Saurabh Sharma Anusuya Bhattacharyya Subodh Kumar Amit Raj Sharma Pramod Avti Bikash Medhi Source Type: research
Current concepts and molecular mechanisms in pharmacogenetics of essential hypertension
Farhana Rahman, Nagasundaram Muthaiah, Govindasamy KumaramanickavelIndian Journal of Pharmacology 2021 53(4):301-309
Hypertension is a leading age-related disease in our society and if left untreated, leads to fatal cardiovascular complications. The prevalence of hypertension has increased and becomes a significant global health economic burden, particularly in lower-income societies. Many loci associated with blood pressure and hypertension have been reported by genome-wide association studies that provided potential targets for pharmacotherapy. Pharmacogenetic research had shown interindividual variations in drug effica...
Source: Indian Journal of Pharmacology - August 18, 2021 Category: Drugs & Pharmacology Authors: Farhana Rahman Nagasundaram Muthaiah Govindasamy Kumaramanickavel Source Type: research
Moxifloxacin-induced oral erythema multiforme: An unusual adverse effect hitherto unreported
Somnath Das, Olympia Rudra, Surabhi Sharma, Subhadeep MallickIndian Journal of Pharmacology 2021 53(4):298-300
Moxifloxacin is a fluoroquinolone with excellent activity in community-acquired respiratory tract infections. Common adverse effects are gastrointestinal symptoms, headache, dizziness, etc., Some serious adverse effects include tendon rupture, rhabdomyolysis, peripheral neuropathy, and interstitial nephritis. Cutaneous adverse effects include allergic reactions, angioedema, Steven–Johnson syndrome, and toxic epidermal necrosis. Erythema multiforme (EM), an acute self-limiting disease, most commonly o...
Source: Indian Journal of Pharmacology - August 18, 2021 Category: Drugs & Pharmacology Authors: Somnath Das Olympia Rudra Surabhi Sharma Subhadeep Mallick Source Type: research
Impact of oral anticholinergic on insulin response to oral glucose load in patients with impaired glucose tolerance
Conclusions: Our study findings indicate that insulin secretion is influenced by cholinergic system and that oral anticholinergics may attenuate the late phase insulin activity in varying degrees of glycemic status. (Source: Indian Journal of Pharmacology)
Source: Indian Journal of Pharmacology - August 18, 2021 Category: Drugs & Pharmacology Authors: Sandeep Lahiry Mitali Chatterjee Sudip Chatterjee Source Type: research
Desmodium gyrans dc modulates lipid trafficking in cultured macrophages and improves functional high-density lipoprotein in male wistar rats
CONCLUSION: Overall the results indicated that DGM modulates lipid trafficking and possesses functional HDL enhancing potential through increased Apo-A1 levels and paraoxonase activity. Further, reduced CETP expression and increased expression of SR-B1 suggest the reverse cholesterol transport promoting role of DGM. (Source: Indian Journal of Pharmacology)
Source: Indian Journal of Pharmacology - August 18, 2021 Category: Drugs & Pharmacology Authors: MS Indu Arunaksharan Narayanankutty Smitha K Ramavarma Jeksy Jose Manalil Jose Padikkala Achuthan Chathrattil Raghavamenon Source Type: research
Natural product topical therapy in mitigating imiquimod-induced psoriasis-like skin inflammation-underscoring the anti-psoriatic potential of Nimbolide
CONCLUSION: It is noteworthy that NIM showed a predominant therapeutic effect as compared to other treatment group. To recapitulate, NIM has shown promising activity as an anti-psoriatic agent by remarkably ameliorating inflammation and associated proliferation. (Source: Indian Journal of Pharmacology)
Source: Indian Journal of Pharmacology - August 18, 2021 Category: Drugs & Pharmacology Authors: Nilesh Barku More Nivya Sharma Gauthami Pulivendala Swarna Bale Chandraiah Godugu Source Type: research
