Rhino-orbital-cerebral-mucormycosis in COVID-19: A systematic review

Anusuya Bhattacharyya, Phulen Sarma, Dibya Jyoti Sharma, Karuna Kumar Das, Hardeep Kaur, Manisha Prajapat, Subodh Kumar, Seema Bansal, Ajay Prakash, Pramod Avti, Prasad Thota, Dibbanti Harikrishna Reddy, Bhaswati Sharma Gautam, Bikash MedhiIndian Journal of Pharmacology 2021 53(4):317-327 Since the onset of COVID-19 pandemic, parallel opportunistic infections have also been emerging as another disease spectrum. Among all these opportunistic infection, mucormycosis has become a matter of concern with its rapid increase of cases with rapid spread as compared to pre-COVID-19 era. Cases have been reported in post-COVID-19-related immune suppression along with the presence of comorbidity which adds on the deadly outcome. There is no systematic review addressing the issue of COVID-19-associated mucormycosis. This is the first systematic review of published studies of mucormycosis associated with COVID-19. The aim was to analyze the real scenario of the disease statement including all the published studies from first November 2019 to 30th June to analyze the contemporary epidemiology, clinical manifestations, risk factor, prognosis, and treatment outcome of COVID-19 associated rhino-orbito-cerebral-mucormycosis. A comprehensive literature search was done in following databases, namely, PubMed, Google Scholar, Scopus, and EMBASE using keywords mucormycosis, rhino orbital cerebral mucormycosis, COVID-19, and SARS-CoV-2 (from November 01, 2019 to June 30, 2021). Our study shows that, ...
Source: Indian Journal of Pharmacology - Category: Drugs & Pharmacology Authors: Source Type: research