Antiproliferative effect of Acacia nilotica (L.) leaf extract rich in ethyl gallate against human carcinoma cell line KB
CONCLUSIONS: ANLEE is a prospective source for cancer therapy and therefore should be highlighted to explore on its wide range of safety in rats and efficacy against human carcinoma cell line KB. (Source: Indian Journal of Pharmacology)
Source: Indian Journal of Pharmacology - February 19, 2021 Category: Drugs & Pharmacology Authors: Kalaivani Thiagarajan Shalini Mohan Tapas Kumar Roy Rajasekaran Chandrasekaran Source Type: research
Nonprescription sale of schedule H1 antibiotics in a city of South India
CONCLUSIONS: The present study revealed that the antibiotics are continued to be sold without prescription even after the education program on schedule H1. The deregulation of the act is definitely the problem to be addressed by the government. (Source: Indian Journal of Pharmacology)
Source: Indian Journal of Pharmacology - February 19, 2021 Category: Drugs & Pharmacology Authors: Vineela Chadalavada S Manohar Babu K Balamurugan Source Type: research
To evaluate the efficacy and safety of olopatadine 0.1 & #37; ophthalmic solution and bepotastine 1.5 & #37; ophthalmic solution in patients with vernal keratoconjunctivitis in a tertiary care hospital
CONCLUSIONS: In this study, based on the evaluation of therapeutic performance, bepotastine eye drops proved quicker relief of symptoms and signs compared to olopatadine eye drops but was not statistically significant which would prove beneficial for the patients. (Source: Indian Journal of Pharmacology)
Source: Indian Journal of Pharmacology - February 19, 2021 Category: Drugs & Pharmacology Authors: Vadlakonda Sruthi Resu Neha Reddy K Sowmini Nagur Sharone Grace Source Type: research
Efficacy of valacyclovir and famciclovir in herpes zoster: A comparative study
CONCLUSION: Oral valacyclovir administered during acute zoster infection for a period of 7 days offers significant benefit compared to famciclovir by providing a well tolerated and greater resolution of pain while maintaining the favorable safety profile, making valacyclovir more efficacious and a better drug in management of Herpes Zoster in comparison to famciclovir. (Source: Indian Journal of Pharmacology)
Source: Indian Journal of Pharmacology - February 19, 2021 Category: Drugs & Pharmacology Authors: Ankita Bist A Savitha Kashinath M Gumma Source Type: research
Pregnancy outcomes following exposure to efavirenz based antiretroviral therapy in indian women
CONCLUSION: There was an association of exposure to efavirenz with an increased incidence of adverse pregnancy outcomes, especially LBW infants. This study emphasizes the requirement of large prospective studies to investigate fetomaternal outcomes in pregnant women exposed to efavirenz. (Source: Indian Journal of Pharmacology)
Source: Indian Journal of Pharmacology - February 19, 2021 Category: Drugs & Pharmacology Authors: Rajesh Kumar Mishra Rony Chakravarty Nilopher Siddique Kirit Rajendra Pandey Source Type: research
Regulatory approval for COVID-19 across the globe
Vidya Mahalmani, T Pugazhenthan, Niti Mittal, Shoban Babu Varthya, Bikash MedhiIndian Journal of Pharmacology 2020 52(6):457-466 (Source: Indian Journal of Pharmacology)
Source: Indian Journal of Pharmacology - February 19, 2021 Category: Drugs & Pharmacology Authors: Vidya Mahalmani T Pugazhenthan Niti Mittal Shoban Babu Varthya Bikash Medhi Source Type: research
Fundamentals of experimental pharmacology
Kanwaljit ChopraIndian Journal of Pharmacology 2020 52(5):443-443 (Source: Indian Journal of Pharmacology)
Source: Indian Journal of Pharmacology - December 5, 2020 Category: Drugs & Pharmacology Authors: Kanwaljit Chopra Source Type: research
Are multiple sclerosis therapies safe in severe acute respiratory syndrome coronavirus 2 times ?
Francesco Ferrara, Raffaele La Porta, Priscilla Santilli, Vilma D'Aiuto, Antonio VitielloIndian Journal of Pharmacology 2020 52(5):441-442 (Source: Indian Journal of Pharmacology)
Source: Indian Journal of Pharmacology - December 5, 2020 Category: Drugs & Pharmacology Authors: Francesco Ferrara Raffaele La Porta Priscilla Santilli Vilma D & #39;Aiuto Antonio Vitiello Source Type: research
Drug-induced immune-mediated thrombocytopenia
Harpreet Singh, Deba Prasad Dhibar, Deepak ChaudharyIndian Journal of Pharmacology 2020 52(5):439-440 (Source: Indian Journal of Pharmacology)
Source: Indian Journal of Pharmacology - December 5, 2020 Category: Drugs & Pharmacology Authors: Harpreet Singh Deba Prasad Dhibar Deepak Chaudhary Source Type: research
Chlorambucil-induced psoriasis: A rare entity
Sumir Kumar, Priya Kapoor, Meenakshi BatraniIndian Journal of Pharmacology 2020 52(5):437-438 (Source: Indian Journal of Pharmacology)
Source: Indian Journal of Pharmacology - December 5, 2020 Category: Drugs & Pharmacology Authors: Sumir Kumar Priya Kapoor Meenakshi Batrani Source Type: research
Changing drug regimen during COVID-19 pandemic lockdown: An experience from a Tertiary Eye Care Hospital as a cornea specialist
Bharat Gurnani, Kirandeep KaurIndian Journal of Pharmacology 2020 52(5):435-436 (Source: Indian Journal of Pharmacology)
Source: Indian Journal of Pharmacology - December 5, 2020 Category: Drugs & Pharmacology Authors: Bharat Gurnani Kirandeep Kaur Source Type: research
Photodermatitis in a woman with infiltrating intraductal breast carcinoma: An uncommon adverse cutaneous drug reaction of paclitaxel revisited
Vikram K Mahajan, Vikas Sharma, Dhaarna WadhwaIndian Journal of Pharmacology 2020 52(5):430-434
Paclitaxel-induced photodermatitis is extremely rare despite the frequent use of paclitaxel-trastuzumab combination chemotherapy. A 70-year-old woman with infiltrating intraductal breast cancer developed photodermatitis after ten treatment courses of weekly paclitaxel-trastuzumab combination chemotherapy. Withdrawal of paclitaxel and sun avoidance led to its resolution. A combined effect of solar radiation and enhanced porphyrin synthesis is speculated for photodermatitis in paclitaxel. However, the issue of aberrant porphyrin ...
Source: Indian Journal of Pharmacology - December 5, 2020 Category: Drugs & Pharmacology Authors: Vikram K Mahajan Vikas Sharma Dhaarna Wadhwa Source Type: research
Organoids: An invaluable tool in pharmacology
This article discusses the various aspects of this emerging concept along with its uses, both in the present times and near future, with a special focus on pharmacological applications. (Source: Indian Journal of Pharmacology)
Source: Indian Journal of Pharmacology - December 5, 2020 Category: Drugs & Pharmacology Authors: Sadasivam Balakrishnan Shubham Atal Avik Ray CA Pravin Malaya Nanda Source Type: research
Systematic review and meta-analysis of effectiveness and safety of favipiravir in the management of novel coronavirus (COVID-19) patients
Ajay Prakash, Harvinder Singh, Hardeep Kaur, Ankita Semwal, Phulen Sarma, Anusuya Bhattacharyya, Deba Prasad Dhibar, Bikash MedhiIndian Journal of Pharmacology 2020 52(5):414-421
Multiple options are being tried for the management of 2019-nCoV infection since its pandemic started. Favipiravir (FPV) is one of drugs, which is also being tried for the management of 2019-nCoV infection. The present study aimed to evaluate the efficacy and safety of FPV in published literature. Comparative randomized or nonrandomized controlled clinical trials comparing FPV to the standard of care (SOC)/control or other antiviral agent/combina...
Source: Indian Journal of Pharmacology - December 5, 2020 Category: Drugs & Pharmacology Authors: Ajay Prakash Harvinder Singh Hardeep Kaur Ankita Semwal Phulen Sarma Anusuya Bhattacharyya Deba Prasad Dhibar Bikash Medhi Source Type: research
Antibody & #8211;drug conjugates, cancer immunotherapy, and metronomic chemotherapy as novel approaches in cancer management
Sudhir Chandra Sarangi, Pranav Sopory, Soumya Sucharita Pattnaik, KH ReetaIndian Journal of Pharmacology 2020 52(5):402-413
Treatment of cancer is a major challenge even though the pathophysiology is becoming clearer with time. A number of new chemical entities are developed to target cancer growth inhibition, but the targeted delivery of these products still needs novel research. This is of utmost importance not only for higher efficacy but also for a reduction in systemic toxicity and cost of treatment. Although multiple novel targets and molecules are being researched, most of them could not pass the regulatory approva...
Source: Indian Journal of Pharmacology - December 5, 2020 Category: Drugs & Pharmacology Authors: Sudhir Chandra Sarangi Pranav Sopory Soumya Sucharita Pattnaik KH Reeta Source Type: research
