Correlation between serum pro inflammatory cytokines and clinical scores of knee osteoarthritic patients using resveratrol as a supplementary therapy with meloxicam
CONCLUSION: A weak and nonsignificant correlation between serum biomarkers and the clinical outcomes has been suggested in patients with painful knee OA treated with meloxicam and resveratrol. (Source: Indian Journal of Pharmacology)
Source: Indian Journal of Pharmacology - August 18, 2021 Category: Drugs & Pharmacology Authors: Bushra Hassan Marouf Saad Abdulrahman Hussain Ziyad Serdar Ali Source Type: research
Comparative effectiveness of metoprolol, ivabradine, and its combination in the management of inappropriate sinus tachycardia in coronary artery bypass graft patients
CONCLUSION: Ivabradine stands as a pharmacological option for controlling HR and rhythm without associated side effects in postoperative CABG patients with IST. (Source: Indian Journal of Pharmacology)
Source: Indian Journal of Pharmacology - August 18, 2021 Category: Drugs & Pharmacology Authors: Parloop Bhatt Niren Bhavsar Dhaval Naik Dhiren Shah Source Type: research
Role of Iron Chelators in Mucormycosis
Vidya Mahalmani, Phulen Sarma, Ajay Prakash, Bikash MedhiIndian Journal of Pharmacology 2021 53(4):261-263 (Source: Indian Journal of Pharmacology)
Source: Indian Journal of Pharmacology - August 18, 2021 Category: Drugs & Pharmacology Authors: Vidya Mahalmani Phulen Sarma Ajay Prakash Bikash Medhi Source Type: research
Attitude toward COVID-19 vaccination: A cross-sectional study on healthcare professionals
Suresh Velumani, Patel Arpita, Ramachandran BalaramanIndian Journal of Pharmacology 2021 53(3):250-251 (Source: Indian Journal of Pharmacology)
Source: Indian Journal of Pharmacology - June 22, 2021 Category: Drugs & Pharmacology Authors: Suresh Velumani Patel Arpita Ramachandran Balaraman Source Type: research
Written informed consent to virtual e-consent in clinical research: Changing necessity during COVID times
Apoorva MathurIndian Journal of Pharmacology 2021 53(3):248-249 (Source: Indian Journal of Pharmacology)
Source: Indian Journal of Pharmacology - June 22, 2021 Category: Drugs & Pharmacology Authors: Apoorva Mathur Source Type: research
Potential effects of itolizumab treatment on plasma interleukin-6 levels in patients with severe COVID-19
Yethindra Vityala, Tugolbai Tagaev, Sagynali Mamatov, Ziiabidin Aidarov, Panchadcharam HarinathIndian Journal of Pharmacology 2021 53(3):246-247 (Source: Indian Journal of Pharmacology)
Source: Indian Journal of Pharmacology - June 22, 2021 Category: Drugs & Pharmacology Authors: Yethindra Vityala Tugolbai Tagaev Sagynali Mamatov Ziiabidin Aidarov Panchadcharam Harinath Source Type: research
Candidiasis in patients treated with interleukin-17 inhibitors
Nerea Báez-Gutierrez, Héctor Rodríguez-RamalloIndian Journal of Pharmacology 2021 53(3):244-245 (Source: Indian Journal of Pharmacology)
Source: Indian Journal of Pharmacology - June 22, 2021 Category: Drugs & Pharmacology Authors: Nerea B á ez-Gutierrez H é ctor Rodr í guez-Ramallo Source Type: research
Efficacy and safety of inhaled nitric oxide in the treatment of severe/critical COVID-19 patients: A systematic review
CONCLUSIONS: In patients with COVID-19 with acute respiratory distress syndrome, nitric oxide is linked to a slight increase in oxygenation but has no effect on mortality. (Source: Indian Journal of Pharmacology)
Source: Indian Journal of Pharmacology - June 22, 2021 Category: Drugs & Pharmacology Authors: Ajay Prakash Sukhmeet Kaur Charanjeet Kaur Praisy K Prabha Anusuya Bhatacharya Phulen Sarma Bikash Medhi Source Type: research
A case report on azathioprine-induced euprolactinemic galactorrhea
Deepa Chaudhary, Ratinder JhajIndian Journal of Pharmacology 2021 53(3):234-235
Galactorrhea is characterized as an inappropriate discharge of milk-containing fluid from the breast. It has various causes including physiological and pathological. It may also be caused by many drugs. Although galactorrhea is usually associated with increased serum prolactin levels, it has been reported to occur in the absence of hyperprolactinemia. Cases of azathioprine-induced galactorrhea with normal prolactin level in a 22-year-old female patient with prurigo have been reported. It was noticed that the patient had no history of galactorr...
Source: Indian Journal of Pharmacology - June 22, 2021 Category: Drugs & Pharmacology Authors: Deepa Chaudhary Ratinder Jhaj Source Type: research
The effects of empagliflozin on cardiometabolic risk factors in patients with type 2 diabetes: A short-term observational study
Jithin Chacko, Shankar Dhandapani, Vidhya Jahagiridhar, Krishnan SwaminathanIndian Journal of Pharmacology 2021 53(3):229-233
The aim of this study was to assess the short-term cardiometabolic outcomes in type 2 diabetes patients receiving empagliflozin in a tertiary referral center. Three hundred and fifteen consecutive patients started on empagliflozin were followed for a 4-month period after local ethics committee approval for a range of outcomes. Data were recorded on Microsoft Excel and transposed to SPSS for further analysis. Empagliflozin treatment resulted in statistically significant reductions in weight, glycosy...
Source: Indian Journal of Pharmacology - June 22, 2021 Category: Drugs & Pharmacology Authors: Jithin Chacko Shankar Dhandapani Vidhya Jahagiridhar Krishnan Swaminathan Source Type: research
Can emapalumab be life saving for refractory, recurrent, and progressive cytokine storm caused by COVID-19, which is resistant to anakinra, tocilizumab, and Janus kinase inhibitors
Erkan Cure, Adem Kucuk, Medine Cumhur CureIndian Journal of Pharmacology 2021 53(3):226-228
Although many potent drugs have been used for cytokine storm, mortality is high for patients with coronavirus disease-2019 (COVID-19), which is followed up in the intensive care unit. Interferons (IFNs) are the major cytokines of the antiviral defense system released from many cell types. However, IFN-γ plays a key role in both primary and secondary cytokine storms. If the cytokine storm is not treated urgently, it will be fatal; therefore, it should be treated immediately. Anakinra, an interleukin-1 (IL-1) antagonist, ...
Source: Indian Journal of Pharmacology - June 22, 2021 Category: Drugs & Pharmacology Authors: Erkan Cure Adem Kucuk Medine Cumhur Cure Source Type: research
Copper-lowering agents as an adjuvant in chemotherapy
Pramod Kadu, Bhakti Sawant, Pravin Popatrao Kale, Kedar PrabhavalkarIndian Journal of Pharmacology 2021 53(3):221-225
Copper is an important element essential for metabolism and normal human body function. Although it is an essential element, related imbalance leads to toxic effects. Studies have proved that there is an increase in copper level in cancer cells. Evidences suggest the link between increase in copper levels and progression of various types of cancers. Different strategies have been utilized to decrease the level of copper in various types of cancer cells. However, it was observed that cell machinery involved...
Source: Indian Journal of Pharmacology - June 22, 2021 Category: Drugs & Pharmacology Authors: Pramod Kadu Bhakti Sawant Pravin Popatrao Kale Kedar Prabhavalkar Source Type: research
Evaluation of vanillin as a probe drug for aldehyde oxidase and phenotyping for its activity in a Western Indian Cohort
CONCLUSIONS: Data of the phenotyping study suggest the existence of AO polymorphism, in a Western Indian cohort. (Source: Indian Journal of Pharmacology)
Source: Indian Journal of Pharmacology - June 22, 2021 Category: Drugs & Pharmacology Authors: Sandhya Subash Nithya J Gogtay Krishna R Iyer Prajakta Gandhe Ritu Budania Urmila M Thatte Source Type: research
Effect of combined colistin and meropenem against meropenem resistant Acinetobacter baumannii and Pseudomonas aeruginosa by checkerboard method: A cross sectional analytical study
CONCLUSION: Our results showed that combinations of colistin and meropenem are associated with improvement in minimum inhibitory concentration and may be a promising strategy in treating meropenem-resistant A. baumannii respiratory tract infections. (Source: Indian Journal of Pharmacology)
Source: Indian Journal of Pharmacology - June 22, 2021 Category: Drugs & Pharmacology Authors: Anitha Gunalan Dhandapani Sarumathi Apurba Sankar Sastry Venkateswaran Ramanathan Sathish Rajaa Sujatha Sistla Source Type: research
Nephroprotective effects of ethanolic root extract of Azima tetracantha lam in adenine-induced chronic kidney failure in Wistar rats
CONCLUSION: EEATR was found to be an effective nephroprotective agent in adenine-induced chronic renal failure in Wistar albino rats. (Source: Indian Journal of Pharmacology)
Source: Indian Journal of Pharmacology - June 22, 2021 Category: Drugs & Pharmacology Authors: Ruckmani Arunachalam Venu Gopala Rao Konda Madhavi Eerike Arun Kumar Radhakrishnan Sobita Devi Source Type: research
