Retrospective pharmacovigilance analysis of nonsteroidal anti-inflammatory drugs-induced chronic kidney disease
CONCLUSION: The present study revealed that prolonged use of NSAIDs in chronic pain conditions was responsible for CKD. To reduce the risk of NSAIDs-induced CKD, health care professionals should take the necessary steps to improve patient safety. (Source: Indian Journal of Pharmacology)
Source: Indian Journal of Pharmacology - June 22, 2021 Category: Drugs & Pharmacology Authors: Vardhipathi Sravana Swathi Shrishti Saroha Jai Prakash Shashi Bhushan Source Type: research
Antimicrobial resistance: An unseen threat prowling behind the COVID-19 outbreak
Vidya Mahalmani, J Kumaravel, Manav Jain, Ajay Prakash, Bikash MedhiIndian Journal of Pharmacology 2021 53(3):187-191 (Source: Indian Journal of Pharmacology)
Source: Indian Journal of Pharmacology - June 22, 2021 Category: Drugs & Pharmacology Authors: Vidya Mahalmani J Kumaravel Manav Jain Ajay Prakash Bikash Medhi Source Type: research
Antimicrobial prescribing in dental practice during COVID 19: Its impact on antimicrobial resistance
Mathur Apoorva, Gupta Yogendra KumarIndian Journal of Pharmacology 2021 53(2):180-181 (Source: Indian Journal of Pharmacology)
Source: Indian Journal of Pharmacology - May 26, 2021 Category: Drugs & Pharmacology Authors: Mathur Apoorva Gupta Yogendra Kumar Source Type: research
Modified drug regimen for ophthalmic anesthesia during COVID-19 pandemic: Revisiting pharmacological concepts
Bharat Gurnani, Kirandeep KaurIndian Journal of Pharmacology 2021 53(2):178-179 (Source: Indian Journal of Pharmacology)
Source: Indian Journal of Pharmacology - May 26, 2021 Category: Drugs & Pharmacology Authors: Bharat Gurnani Kirandeep Kaur Source Type: research
Randomized trial of vilazodone versus sertraline in depression: concerns and comments
Samir Kumar PraharajIndian Journal of Pharmacology 2021 53(2):176-177 (Source: Indian Journal of Pharmacology)
Source: Indian Journal of Pharmacology - May 26, 2021 Category: Drugs & Pharmacology Authors: Samir Kumar Praharaj Source Type: research
Dapagliflozin-induced long-term and severe anorexia and weight loss: An extraordinary case
Erkan Cure, Hakan Sirin, Medine Cumhur Cure, Dursun Ali SahinIndian Journal of Pharmacology 2021 53(2):174-175 (Source: Indian Journal of Pharmacology)
Source: Indian Journal of Pharmacology - May 26, 2021 Category: Drugs & Pharmacology Authors: Erkan Cure Hakan Sirin Medine Cumhur Cure Dursun Ali Sahin Source Type: research
Unmet needs of corneal collagen cross-linking
Tapasya SinghaIndian Journal of Pharmacology 2021 53(2):173-173 (Source: Indian Journal of Pharmacology)
Source: Indian Journal of Pharmacology - May 26, 2021 Category: Drugs & Pharmacology Authors: Tapasya Singha Source Type: research
Fixed-dose combinations: An essential for rational preparation
Pugazhenthan Thangaraju, Shoban Babu Varthya, Sajitha VenkatesanIndian Journal of Pharmacology 2021 53(2):170-172 (Source: Indian Journal of Pharmacology)
Source: Indian Journal of Pharmacology - May 26, 2021 Category: Drugs & Pharmacology Authors: Pugazhenthan Thangaraju Shoban Babu Varthya Sajitha Venkatesan Source Type: research
Current status of in silico, preclinical and clinical study registries across the globe: A systematic review and meta-analysis
Conclusion: At priori study registration is essential to deal with selective reporting. Comparison between study protocol and final report allows us to know the protocol deviations and allows us to evaluate risk of bias and internal validity of the research findings. Although trialists are responsible for the completeness of records, yet the registries must have some measures for their periodic update and quality control of the data. (Source: Indian Journal of Pharmacology)
Source: Indian Journal of Pharmacology - May 26, 2021 Category: Drugs & Pharmacology Authors: Hardeep Kaur Phulen Sarma Manpreet Kaur Manisha Anusuya Bhattacharya Manisha Prajapat Subodh Kumar Ashutosh Singh Rahul Singh Harish Kumar Prasad Thota Ajay Prakash Bikash Medhi Source Type: research
Liposomal amphotericin B-induced reversible ototoxicity in a patient with disseminated histoplasmosis
We report a case of disseminated histoplasmosis who was treated with liposomal amphotericin B (LAmB) and developed hearing loss during the treatment, which recovered after discontinuing the drug. This is a rare adverse effect of LAmB and reported only once from India, to the best of our knowledge. (Source: Indian Journal of Pharmacology)
Source: Indian Journal of Pharmacology - May 26, 2021 Category: Drugs & Pharmacology Authors: Ramadoss Ramu Brijesh Sharma Dheeresh Karunakara Purnima Paliwal Naman Bansal Rajesh Satyapal Taneja Source Type: research
Ropivacaine induced systemic toxicity in a patient with phacomatosis pigmentokeratotica
Ashish Aditya, Paritosh Amar, Anjuman Chander, Nitika Goel, Kajal Jain, Tanvir SamraIndian Journal of Pharmacology 2021 53(2):153-156
Calculation of the maximum recommended dose of local anesthetic minimizes the risk of Local Anesthetic Systemic Toxicity (LAST) when administrating multiple blocks for lower limb surgeries. Ropivacaine is the preferred local anesthetic as it is less lipophilic than bupivacaine and thus results in less central nervous system (CNS) and cardiovascular toxicity. The presence of developmental, congenital, and metabolic disorders mandates an extracautious approach in the administration of large v...
Source: Indian Journal of Pharmacology - May 26, 2021 Category: Drugs & Pharmacology Authors: Ashish Aditya Paritosh Amar Anjuman Chander Nitika Goel Kajal Jain Tanvir Samra Source Type: research
Adverse event reporting tools and regulatory measures in India through outcome of Pharmacovigilance Programme of India
This article provides an overview of adverse events reporting tools in India vis-a-vis selected countries around the world, based on a comparative literature search. This article also throws light upon the regulatory aspects of PV in India, findings of PvPI and its recommendations to Central Drugs Standard Control Organization, collaboration of PvPI with Public Health Programmes, future prospects of reporting ADRs in India and how it will help enhance the quality of ADR-reporting by citizens of India. (Source: Indian Journal of Pharmacology)
Source: Indian Journal of Pharmacology - May 26, 2021 Category: Drugs & Pharmacology Authors: Jai Prakash Raghav Sachdeva Tarani Prakash Shrivastava CV Jayachandran Aseem Sahu Source Type: research
Therapeutic potential of diosmin, a citrus flavonoid against arsenic-induced neurotoxicity via suppression of NOX 4 and its subunits
Conclusions: Treatment with DSN showed a beneficial effect in protecting against arsenic-induced neurotoxicity by suppressing the toxicity changes and the antioxidant effect of DSN might be attributed to its ability of suppressing NOX4 and its subunits. (Source: Indian Journal of Pharmacology)
Source: Indian Journal of Pharmacology - May 26, 2021 Category: Drugs & Pharmacology Authors: Rupasree Peruru Sujatha Dodoala Source Type: research
Development of a psoriatic-like skin inflammation rat model using imiquimod as an inducing agent
Conclusion: From the overall study, we have successfully developed a psoriatic-like skin inflammation rat model for the first time on Wistar strain using IMQ as an inducing agent. (Source: Indian Journal of Pharmacology)
Source: Indian Journal of Pharmacology - May 26, 2021 Category: Drugs & Pharmacology Authors: Komal M Parmar Chetan S Jagtap Nitin T Katare Mahaveer Dhobi Satyendra K Prasad Source Type: research
Questionnaire-based Pan-India survey for impact assessment of National Formulary of India
Conclusion: As per the survey findings, NFI is an effective tool for instant access to precise and unbiased drug-related information, and fostering rational use of drugs. Boosting its practical usefulness needs incorporation of suggested information, digital accessibility, and periodic update. (Source: Indian Journal of Pharmacology)
Source: Indian Journal of Pharmacology - May 26, 2021 Category: Drugs & Pharmacology Authors: Sudhir Chandra Sarangi Bikash Medhi Ajay Prakash Jai Prakash Yogendra K Gupta Source Type: research
