Evaluation and optimization of antibiotic usage in upper respiratory tract infections in children at a tertiary care outpatient department: A clinical audit
CONCLUSION: Interventions through clinical audit were useful in reducing APR. The APR of 8.7% achieved in this study postintervention can be used as a benchmark by other institutions to assess APR in children with URTI. (Source: Indian Journal of Pharmacology)
Source: Indian Journal of Pharmacology - March 18, 2022 Category: Drugs & Pharmacology Authors: Sudhir Mishra Preeti Srivastava Sarala Sunder Asit Kumar Mishra Sanjay Kumar Tanti Source Type: research
Efficacy and acceptability of pomegranate effervescent granules in patients suffering from acid peptic disorders
CONCLUSION: PEGs proved to be palatable, patient-friendly, safe, and efficacious in resolving symptoms of dyspepsia in acid peptic disorders.
CTRI Registration: The trial was registered retrospectively in the Clinical Registry of India [CTRI/2017/07/008999]. (Source: Indian Journal of Pharmacology)
Source: Indian Journal of Pharmacology - March 18, 2022 Category: Drugs & Pharmacology Authors: Poonam Ashish Gupte Madhavi Prabhakar Mahajan Minakshi Subhash Revadkar Kole Ajitkumar Harichand Mandlecha Pratima Arun Tatke Vikram Andrew Naharwar Supriya Sudhakar Bhalerao Source Type: research
Integrative omics & #8211; An arsenal for drug discovery
Rahul Soloman Singh, Vani Angra, Ashutosh Singh, Gladson David Masih, Bikash MedhiIndian Journal of Pharmacology 2022 54(1):1-6 (Source: Indian Journal of Pharmacology)
Source: Indian Journal of Pharmacology - March 18, 2022 Category: Drugs & Pharmacology Authors: Rahul Soloman Singh Vani Angra Ashutosh Singh Gladson David Masih Bikash Medhi Source Type: research
Heparin-induced hyponatremia in COVID-19: A latent culprit!
Rajesh Panda, Pooja Singh, Saiteja Kodamanchili, Abhijeet AnandIndian Journal of Pharmacology 2021 53(6):515-516 (Source: Indian Journal of Pharmacology)
Source: Indian Journal of Pharmacology - December 30, 2021 Category: Drugs & Pharmacology Authors: Rajesh Panda Pooja Singh Saiteja Kodamanchili Abhijeet Anand Source Type: research
Empty vials make most sound: Empty sterile hyaluronidase vials demand quality check
Neeti Dogra, Sumit KumarIndian Journal of Pharmacology 2021 53(6):513-514 (Source: Indian Journal of Pharmacology)
Source: Indian Journal of Pharmacology - December 30, 2021 Category: Drugs & Pharmacology Authors: Neeti Dogra Sumit Kumar Source Type: research
Acamprosate-induced myoclonic jerks: A rare side effect
Puneet Kumar Soni, Lokesh Kumar Singh, Shrayasi Das, Neethu K NandanIndian Journal of Pharmacology 2021 53(6):511-512 (Source: Indian Journal of Pharmacology)
Source: Indian Journal of Pharmacology - December 30, 2021 Category: Drugs & Pharmacology Authors: Puneet Kumar Soni Lokesh Kumar Singh Shrayasi Das Neethu K Nandan Source Type: research
COVID-19 & #8211;associated rhino-orbital-cerebral mucormycosis: A systematic review, meta-analysis, and meta-regression analysis
CONCLUSION: Although local rhino-orbito symptoms were the first to appear, rapid intracranial extension was seen in a significant number of C-ROCM cases. Uncontrolled diabetes and excessive use of corticosteroid were the most common risk factors present among the C-ROCM cases. High index clinical suspicion is imperative (specifically among COVID-19 patients with diabetes), and routine screening may be helpful. (Source: Indian Journal of Pharmacology)
Source: Indian Journal of Pharmacology - December 30, 2021 Category: Drugs & Pharmacology Authors: Anusuya Bhattacharyya Phulen Sarma Hardeep Kaur Subodh Kumar Jaimini Bhattacharyya Manisha Prajapat Ajay Prakash Saurabh Sharma Dibbanti Harikrishna Reddy Prasad Thota Seema Bansal Bhaswati Sharma Gautam Bikash Medhi Source Type: research
Chemoprophylaxis against COVID-19 among health-care workers using Ivermectin in low- and middle-income countries: A systematic review and meta-analysis
Taoreed Adegoke Azeez, Sulaiman Lakoh, Adedapo Adegboyega Adeleke, Oluwanifemi Tolulase Balogun, Babatunde John Olanipekun, Fiyinfoluwa Ibukun OlusolaIndian Journal of Pharmacology 2021 53(6):493-498
Coronavirus disease-2019 (COVID-19) is a novel viral infectious disease that the World Health Organization (WHO) has announced to be a pandemic. This meta-analysis was aimed at providing evidence for the use of ivermectin to prevent COVID-19 among hospital workers in low-resource countries. Medical databases including African Journals online, Google Scholar, PubMed, Cochrane library, EMBASE, COVID-19 research database (WHO), ...
Source: Indian Journal of Pharmacology - December 30, 2021 Category: Drugs & Pharmacology Authors: Taoreed Adegoke Azeez Sulaiman Lakoh Adedapo Adegboyega Adeleke Oluwanifemi Tolulase Balogun Babatunde John Olanipekun Fiyinfoluwa Ibukun Olusola Source Type: research
Nicolau syndrome following subcutaneous glatiramer acetate injection: A case report and review of the literature
Pelin Esme, Irfan Gahramanov, Egemen Akıncıoglu, Gulsen AkogluIndian Journal of Pharmacology 2021 53(6):489-492
Nicolau syndrome is a rare serious drug reaction associated with the administering various injectable medications. It is often characterized by an acute and severe pain accompanying erythema that tends to rapidly evolve into the livedoid reticular or hemorrhagic patches and less commonly to ulcers and skin necrosis. Herein, we report a 34-year-old woman who presented with painful, tender discoloration over her abdominal skin following subcutaneous glatiramer acetate injection. Since the p...
Source: Indian Journal of Pharmacology - December 30, 2021 Category: Drugs & Pharmacology Authors: Pelin Esme Irfan Gahramanov Egemen Ak & #305;nc & #305;oglu Gulsen Akoglu Source Type: research
Clinical profile and role of C-reactive protein and lactate dehydrogenase as prognostic marker and comparative efficacy of different pharmacotherapeutic agents in patients with cerebrovascular accident: An observational study
Dibya Jyoti Sharma, K Jeenaleima Singha, Karuna Das, Chandrama Das, M RakeshIndian Journal of Pharmacology 2021 53(6):484-488
The current study was conducted to determine the role of C-reactive protein (CRP) and lactate dehydrogenase (LDH) as prognostic-marker and outcomes of different pharmacotherapeutic agents among patients with cerebrovascular accident (CVA). A hospital-based observational study was conducted and patients with CVA admitted were included. Serum-CRP on admission correlated positively with modified Rankin score (mRS) (r = 0.9, P < 0.001) in ischemic stroke, whereas no correlation be...
Source: Indian Journal of Pharmacology - December 30, 2021 Category: Drugs & Pharmacology Authors: Dibya Jyoti Sharma K Jeenaleima Singha Karuna Das Chandrama Das M Rakesh Source Type: research
A preliminary study on urinary excretion patterns of methylprednisolone after oral and intra-articular administration and effect on endogenous glucocorticosteroids profile
CONCLUSION: The findings reveal that the MP can exceed the reporting level in urine even after administration by permitted route (i.a.). Further analysis of four endogenous GCs (Cortisol, Cortisone, TH Cortisone, and 11-deoxycortisol) showed a decreased excretion following administration of MP by oral & intra-articular routes. (Source: Indian Journal of Pharmacology)
Source: Indian Journal of Pharmacology - December 30, 2021 Category: Drugs & Pharmacology Authors: Awanish Kumar Upadhyay Sachin Dubey Shobha Ahi Alka Beotra Akhilesh Bhardwaj Sangeeta Shukla Shila Jain Source Type: research
In silico binding analysis of lutein and rosmarinic acid against envelope domain III protein of dengue virus
CONCLUSION: RA is a competent candidate for further evaluation of potential in vitro antiviral activity that can be effective in conferring protection against the four serotypes of DENV. (Source: Indian Journal of Pharmacology)
Source: Indian Journal of Pharmacology - December 30, 2021 Category: Drugs & Pharmacology Authors: Ritesh Panchal Sanket Bapat Sandeepan Mukherjee Abhay Chowdhary Source Type: research
Pharmacodynamic and pharmacokinetic interaction of losartan with glimepiride-metformin combination in rats and rabbits
CONCLUSION: It can therefore be concluded, that in diabetics with hypertension as a comorbidity condition, co-administration of losartan with glimepiride + metformin should be avoided or the dosage of a combination of glimepiride + metformin needs to be tittered to avoid recurrence of hypoglycemic episodes. (Source: Indian Journal of Pharmacology)
Source: Indian Journal of Pharmacology - December 30, 2021 Category: Drugs & Pharmacology Authors: Beere Nagaraju KV Anilkumar Source Type: research
Anxiolytic effects of silibinin and naringenin on zebrafish model: A preclinical study
CONCLUSION: The flavonoids, silibinin, and naringenin were found to mitigate acute stress-induced anxiety, owing to their anxiolytic properties in the zebrafish model and may be explored as the potential therapeutic agents for treating anxiety. (Source: Indian Journal of Pharmacology)
Source: Indian Journal of Pharmacology - December 30, 2021 Category: Drugs & Pharmacology Authors: V Nachammai Srikanth Jeyabalan Sivakumar Muthusamy Source Type: research
Efficacy of Phyllanthus niruri on improving liver functions in patients with alcoholic hepatitis: A double-blind randomized controlled trial
CONCLUSION: A 4-week administration of P. niruri in mild–moderate alcoholic hepatitis patients showed an improvement in the total antioxidant levels with an appetite stimulant activity compared to a placebo. (Source: Indian Journal of Pharmacology)
Source: Indian Journal of Pharmacology - December 30, 2021 Category: Drugs & Pharmacology Authors: Karri Sowjanya Chandrashekaran Girish Chanaveerappa Bammigatti Nakka Chandrasekhar Prasanna Lakshmi Source Type: research
