Prediction of pharmacokinetic values of two various dosages of caffeine in premature neonates with apnea
Conclusions: There was overall good agreement between predicted and measured PK values in our study. This study provides an initial demonstration of Simcyp simulation advantage on anticipating of PK parameters. (Source: Indian Journal of Pharmacology)
Source: Indian Journal of Pharmacology - May 26, 2021 Category: Drugs & Pharmacology Authors: Fatemeh Faramarzi Mohammadreza Shiran Mohammadreza Rafati Roya Farhadi Ebrahim Salehifar Maryam Nakhshab Source Type: research

Medication & #8211; A boon or bane: Emergencies due to medication-related visits
Conclusion: The fact that a quarter of the ED visits are due to MRV and that more than half of them are preventable is quite alarming. Diligent patient education by the treating physicians may perhaps help in decreasing the incidence of this deleterious event. (Source: Indian Journal of Pharmacology)
Source: Indian Journal of Pharmacology - May 26, 2021 Category: Drugs & Pharmacology Authors: Mamta Madhiyazhagan Sudhakar Geratala Dhanapal Priya Ganesan Kundavaram Paul Prabhakar Abhilash Source Type: research

Marathon mice: researcher view on potential roles in preclinical research
J Kumaravel, K Sowmini, Pramod Avti, Bikash MedhiIndian Journal of Pharmacology 2021 53(2):99-102 (Source: Indian Journal of Pharmacology)
Source: Indian Journal of Pharmacology - May 26, 2021 Category: Drugs & Pharmacology Authors: J Kumaravel K Sowmini Pramod Avti Bikash Medhi Source Type: research

The CYP2C19 genotypes and its effect on clopidogrel as an anti-platelet drug among the Arab population
Abdullah Alkattan, Yousef Almutairi, Eman Alsalameen, Ahmed Alkhalifah, Fatimah AlghanimIndian Journal of Pharmacology 2021 53(1):85-87 (Source: Indian Journal of Pharmacology)
Source: Indian Journal of Pharmacology - April 28, 2021 Category: Drugs & Pharmacology Authors: Abdullah Alkattan Yousef Almutairi Eman Alsalameen Ahmed Alkhalifah Fatimah Alghanim Source Type: research

Topical antifungal-corticosteroid fixed-drug combinations: Need for urgent action
Proteesh Rana, Manik Ghadlinge, Vandana RoyIndian Journal of Pharmacology 2021 53(1):82-84 (Source: Indian Journal of Pharmacology)
Source: Indian Journal of Pharmacology - April 28, 2021 Category: Drugs & Pharmacology Authors: Proteesh Rana Manik Ghadlinge Vandana Roy Source Type: research

Ranitidine: Is its injunction a warning bell ?
Saubhik Dasukil, Shiwangi Verma, Samapika Routray, Geetanjali Arora, Kiran Kumar BoyinaIndian Journal of Pharmacology 2021 53(1):80-81 (Source: Indian Journal of Pharmacology)
Source: Indian Journal of Pharmacology - April 28, 2021 Category: Drugs & Pharmacology Authors: Saubhik Dasukil Shiwangi Verma Samapika Routray Geetanjali Arora Kiran Kumar Boyina Source Type: research

Implication of nanotechnology-based approaches to combat SARS-CoV-2 infection
Mana Heidari, Mohsen Salmanpour, Ali-Mohammad TamaddonIndian Journal of Pharmacology 2021 53(1):78-79 (Source: Indian Journal of Pharmacology)
Source: Indian Journal of Pharmacology - April 28, 2021 Category: Drugs & Pharmacology Authors: Mana Heidari Mohsen Salmanpour Ali-Mohammad Tamaddon Source Type: research

A rare side effect of levosulpiride: Galactorrhea
Subodh Kumar Mahto, Nagina Agarwal, Kritika Gupta, Biswa Ranjan PatraIndian Journal of Pharmacology 2021 53(1):76-77 (Source: Indian Journal of Pharmacology)
Source: Indian Journal of Pharmacology - April 28, 2021 Category: Drugs & Pharmacology Authors: Subodh Kumar Mahto Nagina Agarwal Kritika Gupta Biswa Ranjan Patra Source Type: research

Cobra venom neutralization by gold nano particle-2-hydroxy-4-methoxy benzoic acid
Kalyani Saha, Sourav Ghosh, Aparna Gomes, Subir Chandra Dasgupta, Antony GomesIndian Journal of Pharmacology 2021 53(1):73-75 (Source: Indian Journal of Pharmacology)
Source: Indian Journal of Pharmacology - April 28, 2021 Category: Drugs & Pharmacology Authors: Kalyani Saha Sourav Ghosh Aparna Gomes Subir Chandra Dasgupta Antony Gomes Source Type: research

Indian contribution toward biomedical research and development in COVID-19: A systematic review
Hardeep Kaur, Manpreet Kaur, Anusuya Bhattacharyya, Manisha Prajapat, Prasad Thota, Phulen Sarma, Subodh Kumar, Gurjeet Kaur, Saurabh Sharma, Ajay Prakash, PK Saifuddin, Bikash MedhiIndian Journal of Pharmacology 2021 53(1):63-72 COVID-19 pandemic led to an unprecedented collaborative effort among industry, academia, regulatory bodies, and governments with huge financial investments. Scientists and researchers from India also left no stone unturned to find therapeutic and preventive measures against COVID-19. Indian pharmaceutical companies are one of the leading manufacturers of vaccine in the world, are utilizing its ca...
Source: Indian Journal of Pharmacology - April 28, 2021 Category: Drugs & Pharmacology Authors: Hardeep Kaur Manpreet Kaur Anusuya Bhattacharyya Manisha Prajapat Prasad Thota Phulen Sarma Subodh Kumar Gurjeet Kaur Saurabh Sharma Ajay Prakash PK Saifuddin Bikash Medhi Source Type: research

Successful treatment of amiodarone-induced hepatic injury with n-acetylcysteine: A case report
This article accentuates the benefits of NAC treatment in drug-induced liver injury. (Source: Indian Journal of Pharmacology)
Source: Indian Journal of Pharmacology - April 28, 2021 Category: Drugs & Pharmacology Authors: Recep Alanli Murat Bulent Kucukay Ozcan Ozdemir Source Type: research

Potential ameliorative effect of Cynodon dactylon (L.) pers on scopolamine-induced amnesia in rats: Restoration of cholinergic and antioxidant pathways
CONCLUSION: C. dactylon extract provides evidence of anti-amnesic activity by the mechanism of decreased acetylcholinesterase enzyme level and increased antioxidant levels in scopolamine-induced amnesia in rats. (Source: Indian Journal of Pharmacology)
Source: Indian Journal of Pharmacology - April 28, 2021 Category: Drugs & Pharmacology Authors: Laxmi A Pattanashetti Basanagouda M Patil Harsha V Hegde Ranjit P Kangle Source Type: research

Increased apoptosis, tumor necrosis factor- & #945;, and DNA damage attenuated by 3 & #39;,4 & #39;-dihydroxyflavonol in rats with brain & #304;schemia-reperfusion
CONCLUSION: The results of the study showed that I/R significantly increased apoptosis, TNF-α, and DNA damage in rats with brain I/R. However, 10 mg/kg intraperitoneal DiOHF treatment improved deterioted parameters. (Source: Indian Journal of Pharmacology)
Source: Indian Journal of Pharmacology - April 28, 2021 Category: Drugs & Pharmacology Authors: Dervis Dasdelen Merve Solmaz Esma Menevse Rasim Mogulkoc Abdulkerim Kasim Baltaci Ender Erdogan Source Type: research

Construction of time-response curve for neuronal and vascular endothelial dysfunction in ovariectomized rats
CONCLUSIONS: Time-response studies measuring behavioral, biochemical, and molecular markers at various time points after ovariectomy reveal that there is a fast onset of neuronal and vascular complications, but the duration of insulin resistance is a relatively late phenomenon. (Source: Indian Journal of Pharmacology)
Source: Indian Journal of Pharmacology - April 28, 2021 Category: Drugs & Pharmacology Authors: Seema Bansal Kanwaljit Chopra Source Type: research

Modulation of Liver P-Glycoprotien Expression May Contribute to Gossypin Protection against Methotrexate-Induced Hepatotoxicity
CONCLUSIONS: Gossypin may be a valuable adjuvant therapy that protects the liver against MTX toxicity through antioxidant, anti-inflammatory, antiapoptotic mechanisms, and mediated P-gp expression reduction. (Source: Indian Journal of Pharmacology)
Source: Indian Journal of Pharmacology - April 28, 2021 Category: Drugs & Pharmacology Authors: Mervat Mohamed Azza Kamal El Sheikh Hanaa Hassanien Mohammed Source Type: research