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Downregulation of circ_0088196 contributes to the development of trophoblastic cells through miR-133b sponging function to affect the AHNAK expression
Conclusion: The current evidence demonstrated that circ_0088196 knockdown facilitated trophoblastic cell development by regulating the levels of miR-133b and AHNAK, suggesting that circ_0088196 promoted the PE progression via the miR-133b/AHNAK axis. (Source: Gynecologic and Obstetric Investigation)
Source: Gynecologic and Obstetric Investigation - October 5, 2022 Category: OBGYN Source Type: research

Ovarian hyperstimulation syndrome after GnRH agonist triggering and freeze-all protocol? Never not, hardly ever. A systematic review of case reports.
In conclusion, the statement that OHSS risk is eliminated when GnRH-a triggering, a freeze all strategy and no hCG in the luteal phase may generate the idea that this event cannot occur. Although rare, these cases have been observed in a relatively short period of time. (Source: Gynecologic and Obstetric Investigation)
Source: Gynecologic and Obstetric Investigation - September 7, 2022 Category: OBGYN Source Type: research

Expression of Concern
Gynecol Obstet Invest (Source: Gynecologic and Obstetric Investigation)
Source: Gynecologic and Obstetric Investigation - September 1, 2022 Category: OBGYN Source Type: research

Effect of hospital case-volume on mortality after ovarian cancer surgery: a population-based retrospective cohort study
This study attempted to reassess and update the association between surgical case-volume and both in-hospital and long-term mortality after ovarian cancer surgery using recent data. Design: This study is a population-based retrospective cohort study. Participants/Material: Data from all adult patients who underwent ovarian cancer surgery in Korea between 2005 and 2019 were obtained from the national database. A total of 24,620 patients underwent ovarian cancer surgery in 362 hospitals during the period. Setting: In-hospital and 1, 3, 5-year mortality were set as primary and secondary outcomes. Methods: Hospitals were c...
Source: Gynecologic and Obstetric Investigation - August 31, 2022 Category: OBGYN Source Type: research

Circ_0002762 accelerates glycolysis metabolism to promote cervical cancer progression via the miR-526b-5p/HK2 axis
Conclusion: Circ_0002762 knockdown inhibited CC progression by regulating miR-526b-5p/HK2 axis, suggesting that circ_0002762 was a promising therapeutic strategy for CC. (Source: Gynecologic and Obstetric Investigation)
Source: Gynecologic and Obstetric Investigation - August 30, 2022 Category: OBGYN Source Type: research

Clinical characteristics and prognosis of cervical cancer patients with human immunodeficiency virus infection: A retrospective study
The objective of this retrospective observational cohort study was to explore the treatment response, survival, and independent prognostic predictors for HIV-positive patients with CC. Design/Participants/Materials/Setting/Methods: This is a retrospective case-control study. Patients with primary CC, treated at Xiangyang Central Hospital, Hubei, China, from June 2013 to June 2019, were reviewed. All included patients were divided into the HIV-positive and HIV-negative groups. The primary outcome was overall survival (OS). A Kaplan-Meier curve was used to evaluate the survival condition. Univariate and multivariate Cox pro...
Source: Gynecologic and Obstetric Investigation - August 29, 2022 Category: OBGYN Source Type: research

Weekly Differences in the Prevalence of a Short Cervix at 18 < sup > +0 < /sup > to 23 < sup > +6 < /sup > Weeks of Gestation in Pregnant Women with and without a History of Preterm Delivery
Conclusion: There is higher prevalence of short cervix when pregnant women are evaluated at 22+0 to 23+6 than at 18+0 to 21+6 weeks of gestation. (Source: Gynecologic and Obstetric Investigation)
Source: Gynecologic and Obstetric Investigation - August 18, 2022 Category: OBGYN Source Type: research

Weekly differences in the prevalence of a short cervix at 18+0 to 23+6 weeks of gestation in pregnant women with and without a history of preterm delivery
Objective: To estimate weekly differences in the prevalence of a short cervix during the period of 18+0 to 23+6 weeks of gestation in pregnant women with and without a history of previous preterm delivery (PTD). Design: Observational study Methods: Setting and participants: 20,002 pregnant women, 18,591 without a history of previous PTD (low risk) and 1,411 with at least one previous PTD (high risk) were evaluated at 18+0 to 23+6 weeks + days of gestation. Weekly differences in the prevalence of a short cervix ( ≤25 mm, ≤20 mm, and ≤15mm) between women with and without previous PTD were estimated. Results: High-ri...
Source: Gynecologic and Obstetric Investigation - August 18, 2022 Category: OBGYN Source Type: research

Ultrasound evaluation of mid-urethral sling position: A potential predictor of outcomes and adverse effects
Conclusions: Ultrasound visualization of MUS is feasible and has the potential to predict outcomes and complications. High sling-LSM distance was associated with exposure and low sling-LSM distance with increased satisfaction rate, probability of voiding dysfunction and recurrent UTI. (Source: Gynecologic and Obstetric Investigation)
Source: Gynecologic and Obstetric Investigation - August 15, 2022 Category: OBGYN Source Type: research

Circ_0061140 Facilitates Adenomyosis Progression by Upregulating LIN28B in vitro
Conclusion: Circ_0061140 contributed to adenomyosis progression by binding to miR-141-3p to induce LIN28B expression in vitro. (Source: Gynecologic and Obstetric Investigation)
Source: Gynecologic and Obstetric Investigation - August 10, 2022 Category: OBGYN Source Type: research

Circ_0061140 facilitates adenomyosis progression by up-regulating LIN28B in vitro
Conclusion: In conclusion, circ_0061140 contributed to adenomyosis progression by binding to miR-141-3p to induce LIN28B expression in vitro. (Source: Gynecologic and Obstetric Investigation)
Source: Gynecologic and Obstetric Investigation - August 10, 2022 Category: OBGYN Source Type: research

Altered endometrial expression of α-inhibin subunit and its co-receptor betaglycan in infertile women with endometriosis
Background: Inhibins and their co-receptor betaglycan are members of the transforming growth factor β superfamily, a group of signaling molecules that control the differentiation of human endometrium in the secretory phase of the menstrual cycle. Objective: Since endometriosis is associated with endometrial dysfunction and infertility, this study aimed at evaluating the expression of α-inhibin a nd betaglycan mRNA and proteins in endometrial samples of infertile women with and without endometriosis. Design: Cross-sectional study. Participants/Materials: Endometrial samples of women with (n=17) and without (n=22) endometr...
Source: Gynecologic and Obstetric Investigation - July 19, 2022 Category: OBGYN Source Type: research

Retraction Statement
Gynecol Obstet Invest (Source: Gynecologic and Obstetric Investigation)
Source: Gynecologic and Obstetric Investigation - July 8, 2022 Category: OBGYN Source Type: research

Age-Adjusted Charlson Comorbidity Index Predicts Survival in Endometrial Cancer Patients
Conclusion: Patients with EC are characterized by a high burden of comorbidities. Comorbidities impact directly survival outcomes. Further attention is needed to improve the active management of comorbidities soon after EC treatments. Interventional studies are needed to improve patients’ outcomes. (Source: Gynecologic and Obstetric Investigation)
Source: Gynecologic and Obstetric Investigation - July 6, 2022 Category: OBGYN Source Type: research

Nodal Assessment in Endometrial Atypical Hyperplasia
Conclusion: The overall risk of nodal metastases in preoperative AH patients was low. Conversely, 9.9% of the preoperative AH patients belonged to the intermediate or high-risk group for EC at the final histological examination. Preoperative cancer risk factors would identify AH patients for whom nodal staging could be suggested.Gynecol Obstet Invest (Source: Gynecologic and Obstetric Investigation)
Source: Gynecologic and Obstetric Investigation - July 6, 2022 Category: OBGYN Source Type: research