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Effect of IL-15-Mediating IFN- γ on HTR-8/SVneo Cells and a Preeclampsia Mouse Model Induced by Lipopolysaccharides
Conclusion: IL-15 inhibition reduced cell apoptosis and increased the invasive and migratory abilities of LPS-induced HTR-8/SVneo cells, thereby alleviating the PE-like phenotype and improving pregnancy outcome.Gynecol Obstet Invest (Source: Gynecologic and Obstetric Investigation)
Source: Gynecologic and Obstetric Investigation - June 9, 2021 Category: OBGYN Source Type: research

Comparison of Insulin, Metformin, and Glyburide on Perinatal Complications of Gestational Diabetes Mellitus: A Systematic Review and Meta-Analysis
Conclusions: This review suggests that metformin can decrease the incidence of perinatal complications, and it should be considered as a generally safe alternative to insulin.Gynecol Obstet Invest (Source: Gynecologic and Obstetric Investigation)
Source: Gynecologic and Obstetric Investigation - May 12, 2021 Category: OBGYN Source Type: research

Contents Vol. 85, 2020
Gynecol Obstet Invest 2020;85:I –VI (Source: Gynecologic and Obstetric Investigation)
Source: Gynecologic and Obstetric Investigation - May 6, 2021 Category: OBGYN Source Type: research

Acknowledgement to Reviewers
Gynecol Obstet Invest 2020;85:510 –512 (Source: Gynecologic and Obstetric Investigation)
Source: Gynecologic and Obstetric Investigation - May 6, 2021 Category: OBGYN Source Type: research

Author Index
Gynecol Obstet Invest 2020;85:509 (Source: Gynecologic and Obstetric Investigation)
Source: Gynecologic and Obstetric Investigation - May 6, 2021 Category: OBGYN Source Type: research

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Gynecol Obstet Invest 2020;85:509 (Source: Gynecologic and Obstetric Investigation)
Source: Gynecologic and Obstetric Investigation - May 6, 2021 Category: OBGYN Source Type: research

Preliminaries
Gynecol Obstet Invest 2020;85:447 –449 (Source: Gynecologic and Obstetric Investigation)
Source: Gynecologic and Obstetric Investigation - May 6, 2021 Category: OBGYN Source Type: research

Oral Desogestrel as Endometrial Preparation before Operative Hysteroscopy: A Systematic Review
The pharmacologic preparation of the endometrium before hysteroscopy may be achieved with the use of various drugs. This systematic review aims to summarize the available evidence regarding the use of desogestrel for endometrial preparation before hysteroscopic procedures. A literature search for suitable articles published in English language from inception of the database until August 2019 was performed using the following databases: PubMed/MEDLINE, EMBASE, the Cochrane Library, and Google Scholar. All original articles concerning desogestrel-only pretreatment before hysteroscopic surgery were considered eligible. Review...
Source: Gynecologic and Obstetric Investigation - May 5, 2021 Category: OBGYN Source Type: research

Translation, Cross-Cultural Adaptation, and Psychometric Evaluation of the Swedish Version of ENDOCARE: An Instrument to Measure Patient Centeredness of Endometriosis Care
Conclusions: Overall, our results indicate that the Swedish version of the ECQ is a usable instrument to measure patient centeredness in endometriosis care, but due to the unstable factor analysis, conclusions based on the dimensions should be made with caution.Gynecol Obstet Invest (Source: Gynecologic and Obstetric Investigation)
Source: Gynecologic and Obstetric Investigation - May 3, 2021 Category: OBGYN Source Type: research

Changes of Serum Sex Hormone-Binding Globulin, Homocysteine, and Hypersensitive CRP Levels during Pregnancy and Their Relationship with Gestational Diabetes Mellitus
Conclusion: Increased Hcy and hs-CRP in the second trimester and decreased SHBG in the first trimester were independent predictors of GDM, which provides a new idea for early prevention and treatment of GDM.Gynecol Obstet Invest (Source: Gynecologic and Obstetric Investigation)
Source: Gynecologic and Obstetric Investigation - April 27, 2021 Category: OBGYN Source Type: research

Measurement of the Uterocervical Angle for Predicting the Latent Period in Pregnancy Exhibiting Premature Membrane Rupture
Conclusions: The UCA, measured by the transvaginal route, can successfully predict latent period in PPROM. Measuring the UCA can be useful to determine the time of corticosteroid administration and to inform patients about the time of birth.Gynecol Obstet Invest (Source: Gynecologic and Obstetric Investigation)
Source: Gynecologic and Obstetric Investigation - April 26, 2021 Category: OBGYN Source Type: research

C-Reactive Protein for Prediction or Early Detection of Pre-Eclampsia: A Systematic Review
Conclusion: CRP is a promising cost-effective biomarker that may be used in the prediction of PE. A CRP level higher than 15 mg/L may suggest initiation of low-dose aspirin in low-risk pregnancies.Gynecol Obstet Invest (Source: Gynecologic and Obstetric Investigation)
Source: Gynecologic and Obstetric Investigation - April 26, 2021 Category: OBGYN Source Type: research

The Association between Maternal/Fetal Insulin Receptor Substrate 1 Gene Polymorphism rs1801278 and Gestational Diabetes Mellitus in a Chinese Population
Conclusions: Our study suggested that maternal/fetal rs1801278 polymorphism ofIRS1 is a modulating factor in GDM; both mothers/fetuses carrying the A allele of rs1801278 may protect the mothers against the development of GDM.Gynecol Obstet Invest (Source: Gynecologic and Obstetric Investigation)
Source: Gynecologic and Obstetric Investigation - April 23, 2021 Category: OBGYN Source Type: research

“A Revolution in Favor of Reproduction”? Gynecology and Obstetrics in the “Third Reich”
During the “Third Reich,” the majority of German gynecologists and obstetricians did not hesitate to put themselves at the service of those in power. In 1933, many gynecologists initially only focused on the fact that the biopolitical objectives of the National Socialists matched their own long-standing de mands for population policy measures and the early detection and prevention of cancer. In addition, cooperating with the Nazis promised the political advancement of the profession, personal advantages, and the honorary title ofVolksgesundheitsf ührer (national health leaders). As a result, gynecologists exchanged re...
Source: Gynecologic and Obstetric Investigation - April 19, 2021 Category: OBGYN Source Type: research

Prof. Ludwig Seitz (1872 –1961): The Last Schriftf ührer (Editor) of the Monatsschrift f ür Geburtshilfe und Gynäkologie ( Monthly Review of Obstetrics and Gynecology ) (1933 –1938) and the First Schriftwalter (Editor) of the Geburtshilfe und Frauenheilkunde ( Obstetrics and Gynecology ) (Starting in 1939)
Gynecol Obstet Invest (Source: Gynecologic and Obstetric Investigation)
Source: Gynecologic and Obstetric Investigation - April 19, 2021 Category: OBGYN Source Type: research