Gynecologic and Obstetric Investigation This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Comparing single-incision midurethral sling with bulking agents for female stress urinary incontinence: rationale for a non-randomised controled trial
Conclusion: By designing a non-randomized patient preference trial, we not only expect to demonstrate high patient satisfaction with both interventions, but also provide insight in the possible role of PAHG-injections in the treatment of female SUI as a first-choice non-conservative treatment. Trial Registration: This study is retrospectively registered at the Dutch Trial Registry on 22-03-2021 under the number NL9353. (Source: Gynecologic and Obstetric Investigation)
Source: Gynecologic and Obstetric Investigation - January 30, 2023 Category: OBGYN Source Type: research

Contents
Gynecol Obstet Invest 2022;87:I –VI (Source: Gynecologic and Obstetric Investigation)
Source: Gynecologic and Obstetric Investigation - January 26, 2023 Category: OBGYN Source Type: research

Acknowledgement to reviewers
Gynecol Obstet Invest 2022;87:411 –412 (Source: Gynecologic and Obstetric Investigation)
Source: Gynecologic and Obstetric Investigation - January 26, 2023 Category: OBGYN Source Type: research

Evaluation of a web-based intervention for patients with Gestational Trophoblastic Disease: a randomized controlled trial
Conclusions The online tool did not change illness perception, but was shown to be valuable for newly-diagnosed GTD patients to gain knowledge. The improvement in knowledge after digital education, indicates that this tool can be used as an effective method of supporting GTD patients ’ informational needs without causing extra distress. (Source: Gynecologic and Obstetric Investigation)
Source: Gynecologic and Obstetric Investigation - January 20, 2023 Category: OBGYN Source Type: research

Inhibition of ceramide kinase is effectively against cisplatin-resistant ovarian cancer cells by regulating ceramide and C1P levels
Conclusions: Our work is the first to show the critical role of CerK as the underlying mechanism of ovarian cancer chemoresistance, through regulating ceramide and C1P. (Source: Gynecologic and Obstetric Investigation)
Source: Gynecologic and Obstetric Investigation - January 20, 2023 Category: OBGYN Source Type: research

Efficacy, adverse events, and challenges of Dienogest in the management of symptomatic adenomyosis: A comparison with different hormonal treatments
Conclusions and Outlook DNG represents an important therapeutic option to be included in the treatment algorithm for adenomyosis owing to sufficient pain relief, despite high rates of bleeding-related adverse events. Clinicians should consider an individual ’s potential risk factors for bleeding until high-quality evidence is available. (Source: Gynecologic and Obstetric Investigation)
Source: Gynecologic and Obstetric Investigation - January 20, 2023 Category: OBGYN Source Type: research

COVID-19 quarantine and sexual function after first vaginal delivery
Conclusions COVID-19 quarantine did not seem to have a significant effect on female or male sexual function, three to nine months after the first vaginal delivery. The current study is the first to discride primiparous postpartum sexual function as median ASEX score. (Source: Gynecologic and Obstetric Investigation)
Source: Gynecologic and Obstetric Investigation - January 13, 2023 Category: OBGYN Source Type: research

The Utility of Preoperative Serum CA125 Combined with HE4 to Predict Lymph Node Metastasis in Endometrial Cancer
Objectives: To investigate the diagnostic performance of the serum cancer antigen 125 (CA125), human epididymis protein 4 (HE4), a combination of CA125 and HE4, and a Risk of Ovarian Malignancy Algorithm (ROMA) in the preoperative prediction of high-risk lymph node metastasis in patients with early-stage endometrial cancer (EC). Designs: This is a cross-sectional study Participants/Materials, Setting, and Methods: A cross-sectional study of data for patients with early-stage endometrioid EC treated surgically at Rajavithi Hospital between April 2020 and April 2021 was commenced. The preoperative serum levels of CA125 and...
Source: Gynecologic and Obstetric Investigation - January 3, 2023 Category: OBGYN Source Type: research

OnabotulinumtoxinA Injections for the Treatment of Myofascial Pelvic Pain: 12-year Experience at a Tertiary Care Academic Center
CONCLUSION: OnabotulinumtoxinA is beneficial in treating women with MFPP; with a duration of therapeutic effect of approximately 6 months. The use of a concurrent pudendal nerve block did not impact clinical outcomes. (Source: Gynecologic and Obstetric Investigation)
Source: Gynecologic and Obstetric Investigation - December 28, 2022 Category: OBGYN Source Type: research

LINC01857 exacerbates the malignant behaviors of endometrial carcinoma cells by sponging miR-19b-3p and recruiting ELAVL1 to up-regulate MYCN
Conclusions: LINC01857 exacerbated EC cell malignant behaviors via the miR-19b-3p/ELAVL1/MYCN axis. (Source: Gynecologic and Obstetric Investigation)
Source: Gynecologic and Obstetric Investigation - December 27, 2022 Category: OBGYN Source Type: research

Role of Protopine and Nuciferine in the Management of Nocturia, Urgency, and Dysuria in Pre- and Postmenopausal Women: A Prospective Pilot Study
Conclusions: Protopine and nuciferine can be an interesting alternative to primarily treat and reduce nocturia episodes, in addition to improving OAB-related urgency and dysuria.Gynecol Obstet Invest (Source: Gynecologic and Obstetric Investigation)
Source: Gynecologic and Obstetric Investigation - December 19, 2022 Category: OBGYN Source Type: research

Role of Protopine and Nuciferine in the management of nocturia, urgency and dysuria in pre- and post-menopausal women: a prospective pilot study.
Abstract Objectives: Nocturia was commonly treated with drugs burdened with high costs and numerous side effects; in fact, more than 70% of patients drop out of long-term treatment. Protopine and Nuciferine are two alkaloids that have different effects on the neurotransmitter receptors involved in the regulation mechanism of the onset of urinary stimuli. The aim of the study is to evaluate the efficacy in controlling primarily nocturia and secondarily urgency and dysuria after three months of treatment with combination therapy of protopine and nuciferine syrup. Design: This is a prospective cohort study in which all pati...
Source: Gynecologic and Obstetric Investigation - December 19, 2022 Category: OBGYN Source Type: research

Myo-Inositol Enhances the Inhibitory Effect of Metformin on Gonadotropin Levels in Postmenopausal Women
Conclusions: Myo-inositol may enhance the inhibitory effect of metformin on gonadotropin production in postmenopausal women.Gynecol Obstet Invest (Source: Gynecologic and Obstetric Investigation)
Source: Gynecologic and Obstetric Investigation - December 14, 2022 Category: OBGYN Source Type: research