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Efficacy and Safety of Intravenous Tramadol versus Intravenous Paracetamol for Relief of Acute Pain of Primary Dysmenorrhea: A Randomized Controlled Trial
Conclusions: IV tramadol is superior to IV paracetamol in relieving acute pain of primary dysmenorrhea with a comparable side effect profile.Gynecol Obstet Invest (Source: Gynecologic and Obstetric Investigation)
Source: Gynecologic and Obstetric Investigation - October 19, 2020 Category: OBGYN Source Type: research

Identification of Long Noncoding RNA Expression Profiles in HPV-Negative Cervical Cancer
Conclusion: LINC00115 might be a potential biomarker for HPV-negative CC.Gynecol Obstet Invest (Source: Gynecologic and Obstetric Investigation)
Source: Gynecologic and Obstetric Investigation - October 14, 2020 Category: OBGYN Source Type: research

Diagnostic Relevance of Ferrokinetic Laboratory Markers in Anemic Pregnant Women
Conclusions: Determination of iron deficiency in pregnant women at different gestational periods will allow for identifying the risk group of anemic patients and deciding on the treatment. IDA (Hb #x3c;100 g/L) can be effectively measured by ferritin level #x3c;15 ng/mL, iron level of #x3c;11.5 μmol/L, and transferrin level #x3e;2.6 mg/L atp #x3c; 0.001. Anemia due to chronic diseases (Hb #x3c;100 g/L) can be effectively diagnosed with ferritin above 15 μg/L and CRP above 10 mg/L atp #x3c; 0.001.Gynecol Obstet Invest (Source: Gynecologic and Obstetric Investigation)
Source: Gynecologic and Obstetric Investigation - October 2, 2020 Category: OBGYN Source Type: research

Nuclear Atypia Is a Necessary Factor for Diagnosis of Primary Ovarian Fibrosarcoma: A Case Report and Literature Review
Conclusions: Herein we report a case of primary ovarian fibrosarcoma and reviewed all published cases in English. Following the latest trend of diagnosis, multiple prognostic factors were used to determine survival prognosis. These included nuclear atypia, FIGO stage, mitotic counts, treatment methods, and tumor size. Only nuclear atypia was found to be associated with patient prognosis (p #x3c; 0.05). FIGO stage (p = 0.383), mitotic count per 10 hpfs (p = 0.155), treatment methods (p = 0.185), and tumor size (p = 0.972) were not found to be associated with survival prognosis. Nuclear atypia was an important factor in prog...
Source: Gynecologic and Obstetric Investigation - October 2, 2020 Category: OBGYN Source Type: research

Does a Large ( & #x3e;24 mm) Follicle Yield a Competent Oocyte/Embryo?
Conclusion: While a nonsignificant decrease in oocyte recovery rate was found in follicles ≥24 mm, the zygote and TQE per follicle were comparable.Gynecol Obstet Invest (Source: Gynecologic and Obstetric Investigation)
Source: Gynecologic and Obstetric Investigation - September 23, 2020 Category: OBGYN Source Type: research

Altered Expressions of AQP3 and ADP Are Closely Related with the Risk of Preeclampsia Occurrence
To investigate the expression of aquaporin 3 (AQP3) in placenta and fetal membranes and the level of adiponectin (ADP) in the umbilical cord blood of severe preeclampsia and to analyze the relationship between the 2 proteins and severe preeclampsia, 60 pregnant women with severe preeclampsia were recruited as the case group and another group of 60 normal pregnant women in the same gestation period were selected as the control. After parturition, the transcriptional levels of AQP3 mRNA in placenta and fetal membranes were evaluated with RT-PCR. The expressions of AQP3 protein in the placenta and fetal membranes were determi...
Source: Gynecologic and Obstetric Investigation - September 21, 2020 Category: OBGYN Source Type: research

Uterine Isthmus Tourniquet during Abdominal Myomectomy: Support or Hazard? A Randomized Double-Blind Trial
Conclusion: The use of a tourniquet during abdominal myomectomy significantly reduced the mean volume of blood loss compared to the non-tourniquet group, while it did not prolong the duration of surgery, nor reduced the ovarian reserve. A tourniquet is a safe and efficient measure during abdominal myomectomy.Gynecol Obstet Invest (Source: Gynecologic and Obstetric Investigation)
Source: Gynecologic and Obstetric Investigation - September 16, 2020 Category: OBGYN Source Type: research

Incidence of Postoperative Adhesions after Laparoscopic Myomectomy with Barbed Suture
Conclusion: Our data indicated that the incidence of postoperative adhesion following the use of BS for wound closure in laparoscopic myomectomy was similar to that following the use of conventional suture.Gynecol Obstet Invest (Source: Gynecologic and Obstetric Investigation)
Source: Gynecologic and Obstetric Investigation - September 15, 2020 Category: OBGYN Source Type: research

Percutaneous-Assisted versus Laparoscopic Hysterectomy: A Prospective Comparison
Conclusions: In this study, we reported that PSS-H is comparable to LPS-H for intra- and perioperative outcomes and postoperative pain, while PSS-H seems to be superior in cosmetic outcomes and patient satisfaction. PSS-H may represent a valid alternative in ultra-MIS for benign gynecological conditions and low-/intermediate-risk endometrial cancer.Gynecol Obstet Invest (Source: Gynecologic and Obstetric Investigation)
Source: Gynecologic and Obstetric Investigation - September 11, 2020 Category: OBGYN Source Type: research

The Effect of Isotretinoin on Oocyte Maturation in Adolescent Female Rats
Conclusions: In our study, we showed toxic effect of isotretinoin on oocyte maturation in female rats.Gynecol Obstet Invest (Source: Gynecologic and Obstetric Investigation)
Source: Gynecologic and Obstetric Investigation - September 7, 2020 Category: OBGYN Source Type: research

Addition of Fentanyl or High-Dose Morphine to Bupivacaine Is Superior to Bupivacaine Alone during Single-Shot Spinal Anesthesia
Conclusion: The addition of fentanyl or high-dose morphine to bupivacaine increases the efficacy and duration of SSSA in the active phase of progressing labor without increasing side effects.Gynecol Obstet Invest (Source: Gynecologic and Obstetric Investigation)
Source: Gynecologic and Obstetric Investigation - August 11, 2020 Category: OBGYN Source Type: research

COVID-19 (SARS-CoV-2) Infection in Pregnancy: A Systematic Review
Conclusion: COVID-19 infection in pregnancy leads to increased risk in pregnancy complications such as preterm birth, PPROM, and may possibly lead to maternal death in rare cases. There is no evidence to support vertical transmission of SARS-CoV-2 infection to the unborn child. Due to a paucity of inconsistent data regarding the impact of COVID-19 on the newborn, caution should be undertaken to further investigate and monitor possible infection in the neonates born to COVID-19-infected mothers.Gynecol Obstet Invest (Source: Gynecologic and Obstetric Investigation)
Source: Gynecologic and Obstetric Investigation - July 30, 2020 Category: OBGYN Source Type: research

LH Supplementation in Ovarian Stimulation for IVF: The Individual, LH Deficient, Patient Perspective
The availability of recombinant follicle-stimulating hormone (FSH) and luteinizing hormone (LH) opens an opportunity to individualize ovarian stimulation. While the need for FSH in ovarian stimulation is universal, a question remains whether exogenous LH is beneficial. Previous population-based research showed that added LH is indicated in elderly and in profoundly LH depressed patients. This commentary explores potential individual patient parameters that may hint that this specific individual may prospectively need supplemented LH, irrespective of her age or experience from previous cycles. Specifically, it is suggested ...
Source: Gynecologic and Obstetric Investigation - July 21, 2020 Category: OBGYN Source Type: research

Stop GnRH-Agonist Combined with Multiple-Dose GnRH-Antagonist for Patients with Elevated Peak Serum Progesterone Levels Undergoing Ovarian Stimulation for IVF: A Proof of Concept
Conclusions: The combined Stop GnRH-ag/GnRH-ant OS protocol is a valuable tool in the armamentarium for treating patients with progesterone elevation during the late follicular phase. Further large prospective studies are needed to validate our observation and to characterize the appropriate patients ’ subgroup, which might benefit from the combined Stop GnRH-ag/GnRH-ant COH protocol.Gynecol Obstet Invest (Source: Gynecologic and Obstetric Investigation)
Source: Gynecologic and Obstetric Investigation - June 24, 2020 Category: OBGYN Source Type: research

The Many Faces of Endometriosis-Related Neoplasms in the Same Patient: A Brief Report
Conclusions: To the best of our knowledge, the present case represents the first evidence of the simultaneous occurrence of clear-cell carcinoma and low-grade endometrial stromal sarcoma arising within ovarian and uterine endometriotic foci, respectively.Gynecol Obstet Invest (Source: Gynecologic and Obstetric Investigation)
Source: Gynecologic and Obstetric Investigation - June 22, 2020 Category: OBGYN Source Type: research