Lifestyle-associated risk factor and gastrointestinal cancers: targeting potential of the gut microbe-host crosstalk-based metabolic processes
(Source: Gastroenterology)
Source: Gastroenterology - February 8, 2024 Category: Gastroenterology Authors: Ruize Qu, Zhipeng Zhang, Wei Fu Tags: Correspondence Source Type: research
Survival of the fittest: Clonal selection of somatic mutations reveals targets to abate chronic liver injury
(Source: Gastroenterology)
Source: Gastroenterology - February 7, 2024 Category: Gastroenterology Authors: Natalie M. Niemi, Brian J. DeBosch Tags: Gastro Digest Source Type: research
Holding back the tide: Interferon-gamma to the rescue
(Source: Gastroenterology)
Source: Gastroenterology - February 7, 2024 Category: Gastroenterology Authors: Jay R. Thiagarajah Tags: Gastro Digest Source Type: research
Autonomous Artificial Intelligence vs Artificial Intelligence –Assisted Human Optical Diagnosis of Colorectal Polyps: A Randomized Controlled Trial
In this study, autonomous artificial intelligence performed with high accuracy in diagnosing small (1 –5-mm) colorectal polyps during colonoscopies and allowed follow-ups to be scheduled more correctly than when humans decided the final diagnosis. (Source: Gastroenterology)
Source: Gastroenterology - February 6, 2024 Category: Gastroenterology Authors: Roupen Djinbachian, Claire Haumesser, Mahsa Taghiakbari, Heiko Pohl, Alan Barkun, Sacha Sidani, Jeremy Liu Chen Kiow, Benoit Panzini, Simon Bouchard, Erik Deslandres, Abla Alj, Daniel von Renteln Tags: Clinical - Alimentary Tract Source Type: research
Histologic Remission in Inflammatory Bowel Disease and Female Fertility: A Nationwide Study
The findings of this nationwide study suggest that achieving histologic remission of inflammatory bowel disease may improve the chances of conceiving a child, even among women with clinically quiescent disease. (Source: Gastroenterology)
Source: Gastroenterology - February 6, 2024 Category: Gastroenterology Authors: Karl M årild, Jonas Söderling, Olof Stephansson, Jordan Axelrad, Jonas Halfvarson, SWIBREG Study Group, Gabriella Bröms, Jan Marsal, Ola Olén, Jonas F. Ludvigsson Tags: Clinical - Alimentary Tract Source Type: research
Autonomous Artificial Intelligence versus AI Assisted Human optical diagnosis of colorectal polyps: A randomized controlled trial
Artificial intelligence (AI)-based optical diagnosis systems (CADx) have been developed to allow pathology prediction of colorectal polyps during colonoscopies. However, CADx systems have not yet been validated for autonomous performance. Therefore, we conducted a trial comparing Autonomous AI to AI assisted human (AI-H) optical diagnosis. (Source: Gastroenterology)
Source: Gastroenterology - February 6, 2024 Category: Gastroenterology Authors: Roupen Djinbachian, Claire Haumesser, Mahsa Taghiakbari, Heiko Pohl, Alan Barkun, Sacha Sidani, Jeremy Liu Chen Kiow, Benoit Panzini, Simon Bouchard, Erik Deslandres, Abla Alj, Daniel von Renteln Tags: Clinical - Alimentary Tract Source Type: research
A rare cause of abdominal pain and weight loss
(Source: Gastroenterology)
Source: Gastroenterology - February 6, 2024 Category: Gastroenterology Authors: Aashish Chalasani, Theresa Ly, Sudarshan Paramsothy Tags: Electronic Gastro Curbside Consult Source Type: research
Histological remission in inflammatory bowel disease and female fertility: A nationwide study
Inflammatory bowel disease (IBD) is linked to reduced female fertility, but it is unclear how fertility rates vary by histological disease activity. (Source: Gastroenterology)
Source: Gastroenterology - February 6, 2024 Category: Gastroenterology Authors: Karl M årild, Jonas Söderling, Olof Stephansson, Jordan Axelrad, Jonas Halfvarson, SWIBREG Study Group, Gabriella Bröms, Jan Marsal, Ola Olén, Jonas F. Ludvigsson Tags: Clinical - Alimentary Tract Source Type: research
A Rare Cause of Acute Liver Failure
(Source: Gastroenterology)
Source: Gastroenterology - February 6, 2024 Category: Gastroenterology Authors: Y. Gibbens, J. Lake, N. Lim Tags: Electronic Gastro Curbside Consult Source Type: research
Early Initiation of Biologics and Disease Outcomes in Adults and Children With Inflammatory Bowel Diseases: Results From the Epidemiology Group of the Nationwide Israeli Inflammatory Bowel Disease Research Nucleus Cohort
A small advantage for early initiation of biologics was demonstrated in CD, but this was not the case in UC. (Source: Gastroenterology)
Source: Gastroenterology - February 5, 2024 Category: Gastroenterology Authors: Rona Lujan, Rachel Buchuk, Gili Focht, Dotan Yogev, Shira Greenfeld, Amir Ben-Tov, Yiska Loewenberg Weisband, Natan Lederman, Eran Matz, Shomron Ben Horin, Iris Dotan, Daniel Nevo, Dan Turner Tags: Clinical - Alimentary Tract Source Type: research
Novel Approach for Pancreas Transcriptomics Reveals the Cellular Landscape in Homeostasis and Acute Pancreatitis
Digestive enzymes impede single-cell profiling of exocrine pancreas. FixNCut uses reversible fixation to overcome this challenge, allowing us to define cell heterogeneity and dynamic cell states during pancreatitis and establish an acinar-to-ductal metaplasia index. (Source: Gastroenterology)
Source: Gastroenterology - February 5, 2024 Category: Gastroenterology Authors: Katherine J. Aney, Woo-Jeong Jeong, Andres F. Vallejo, Cassandra Burdziak, Ethan Chen, Austin Wang, Pal Koak, Kellie Wise, Kirk Jensen, Dana Pe ’er, Stephanie K. Dougan, Luciano Martelotto, Sahar Nissim Tags: Basic and Translational - Pancreas Source Type: research
Early initiation of biologics and disease outcomes in children and adults with inflammatory bowel diseases: results from the nationwide epi-IIRN cohort
In this nationwide study we explored whether early initiation of biologics is associated with improved outcomes in children and adults with Crohn ’s disease (CD) and ulcerative colitis (UC). (Source: Gastroenterology)
Source: Gastroenterology - February 5, 2024 Category: Gastroenterology Authors: Rona Lujan, Rachel Buchuk, Gili Focht, Dotan Yogev, Shira Greenfeld, Amir Ben-Tov, Yiska Loewenberg Weisband, Natan Lederman, Eran Matz, Shomron Ben Horin, Iris Dotan, Daniel Nevo, Dan Turner Tags: Clinical - Alimentary Tract Source Type: research
A Novel Approach for Pancreas Transcriptomics Reveals the Cellular Landscape in Homeostasis and Acute Pancreatitis
Acinar cells produce digestive enzymes that impede transcriptomic characterization of the exocrine pancreas. Thus, single-cell RNA-sequencing (scRNA-seq) studies of the pancreas underrepresent acinar cells relative to histological expectations, and a robust approach to capture pancreatic cell responses in disease states is needed. We sought to innovate a method that overcomes these challenges to accelerate study of the pancreas in health and disease. (Source: Gastroenterology)
Source: Gastroenterology - February 5, 2024 Category: Gastroenterology Authors: Katherine J. Aney, Woo-Jeong Jeong, Andres F. Vallejo, Cassandra Burdziak, Ethan Chen, Austin Wang, Pal Koak, Kellie Wise, Kirk Jensen, Dana Pe ’er, Stephanie K. Dougan, Luciano Martelotto, Sahar Nissim Tags: Basic and Translational - Pancreas Source Type: research
A Randomized Trial of Two Remote Health Care Delivery Models on the Uptake of Genetic Testing and Impact on Patient-Reported Psychological Outcomes in Families With Pancreatic Cancer: The Genetic Education, Risk Assessment, and Testing (GENERATE) Study
Online genetic education and genetic testing can be used to overcome some health care delivery barriers without negatively affecting anxiety, depression, or cancer worry. (Source: Gastroenterology)
Source: Gastroenterology - February 4, 2024 Category: Gastroenterology Authors: Nicolette J. Rodriguez, C. Sloane Furniss, Matthew B. Yurgelun, Chinedu Ukaegbu, Pamela E. Constantinou, Ileana Fortes, Alyson Caruso, Alison N. Schwartz, Jill E. Stopfer, Meghan Underhill-Blazey, Barbara Kenner, Scott H. Nelson, Sydney Okumura, Alicia Y. Tags: Clinical - Pancreas Source Type: research
Pembrolizumab-Induced Liver Injury: Beyond Immune-Mediated Hepatitis
Question: A 43-year-old man was referred to the liver unit from the oncology department. A year before, he was diagnosed with well differentiated pT4 laryngeal squamous cell carcinoma and underwent a total laryngectomy. Treatment with pembrolizumab every 3 weeks also started, which he was still receiving. He had neither a pre-existing liver condition nor excessive alcohol consumption. (Source: Gastroenterology)
Source: Gastroenterology - February 4, 2024 Category: Gastroenterology Authors: Queralt Herms, Carla Fuster-Anglada, Adri à Juanola Tags: Electronic Curbside Consult Source Type: research
