Association of inflammatory bowel disease and autoimmune primary adrenal insufficiency
To assess the prevalence and association of inflammatory bowel disease (IBD) with autoimmune primary adrenal insufficiency (APAI). (Source: Gastroenterology)
Source: Gastroenterology - January 25, 2024 Category: Gastroenterology Authors: Salman Haider, Daryl Ramai, Saira Shah, Asad Ur Rahman, Moazzam Hussain, Iyad Al-Bustami, Praneeth Bandaru, Denzil Etienne Source Type: research
Deciphering the burden of inflammatory bowel disease landscape (1990-2019) in high income north america: projections, temporal shifts, and a glimpse beyond to 2040
In High-Income North America, IBD ranks as the 6th leading cause of disability and the 9th primary cause of mortality among all digestive diseases. The increasing prevalence in this region underscores the urgent need to address both the clinical and socio-economic challenges of managing this chronic condition in a developed setting. (Source: Gastroenterology)
Source: Gastroenterology - January 25, 2024 Category: Gastroenterology Authors: Rahul Patel, Vivek Roy, Sashank Sai Bollu, Sai Nitya Tejaswi Anne, Pranathi Royal Naradasu, Sneh Patel, Hardik Dineshbhai Desai Source Type: research
Evolving burden of inflammatory bowel disease in women from 1990-2019: global, regional, national variations, age dynamics, and implications for global health
Inflammatory Bowel Disease (IBD), encompassing conditions such as Crohn's disease and ulcerative colitis, has been a growing concern globally. While its burden has been studied extensively, the specific impact on women, who face unique physiological and socio-cultural challenges, remains underexplored. Grasping the global, national, and regional implications of IBD in women across 204 countries and territories provides a comprehensive understanding to guide healthcare strategies and tailor patient management. (Source: Gastroenterology)
Source: Gastroenterology - January 25, 2024 Category: Gastroenterology Authors: Vani Sojitra, Pranathi Royal Naradasu, Krina Manojbhai Patel, Rahul Patel, Sneh Patel, Hardik Dineshbhai Desai Source Type: research
Evolving landscape of inflammatory bowel disease in g20 nations (1990-2019): a comprehensive global assessment
As pivotal players in the global economy, the G20 countries not only lead in economic dynamics but also in health challenges. Recent data reveals an escalating burden of Inflammatory Bowel Disease (IBD) in these nations. Understanding this trend is crucial to frame healthcare strategies and ensure the well-being of a significant portion of the global population. (Source: Gastroenterology)
Source: Gastroenterology - January 25, 2024 Category: Gastroenterology Authors: Rahul Patel, Krishna Sajeev, Vani Sojitra, Krina Manojbhai Patel, Pranathi Royal Naradasu, Sneh Patel, Hardik Dineshbhai Desai Source Type: research
Exploring factors associated with serological response to sars-cov-2 vaccines in individuals with inflammatory bowel disease: interactive visualization methods for multidimensional data
SARS-CoV-2 vaccine response may be reduced in seniors (age 65+) with inflammatory bowel disease (IBD) and those on anti-TNF therapy. A challenge of the COVID-19 era has been conveying rapid-evolving health information, especially for groups with higher risk of poor outcomes of COVID-19 such as seniors and immunocompromised individuals. (Source: Gastroenterology)
Source: Gastroenterology - January 25, 2024 Category: Gastroenterology Authors: Lindsay Hracs, Joshua Quan, Christopher Ma, Remo Panaccione, Nastaran Sharifi, Michelle Herauf, Ante Markovinovic, Stephanie Coward, Joseph Windsor, Lea Caplan, Julia Gorospe, Kenneth Ernest-Suarez, Richard Ingram, Jessalyn Holodinsky, Charles Bernstein, Source Type: research
Hospital readmission and mortality rates in patients with concurrent depression and inflammatory bowel disease: insights from the national readmissions database, 2016 –2019
Inflammatory Bowel Disease (IBD) is a proinflammatory condition that is known to be associated with depression. Research examining causality suggests that Crohn's disease (CD) or ulcerative colitis (UC) patients are vulnerable to triggering pre-existing mental health conditions and that conversely, a pre-existing disorder such as depression may have an effect on the disease process and course of IBD. There is a paucity of comprehensive studies examining the downstream effects of depression on patients with IBD such as readmission rates and mortality. (Source: Gastroenterology)
Source: Gastroenterology - January 25, 2024 Category: Gastroenterology Authors: Jason John, Kirti Dasu, Akshay Kapoor, Yaser Khalid, Neethi Dasu, Brian Blair, Lucy Joo Source Type: research
Machine learning classification of the epidemiologic stages of inflammatory bowel disease across geography and time
Epidemiologic stages of inflammatory bowel disease (IBD) have been proposed: 1. Emergence (low incidence and prevalence); 2. Acceleration in Incidence (rapidly rising incidence, low prevalence); and 3. Compounding Prevalence (stabilizing incidence, rapidly rising prevalence). To date, these stages have been theoretical without quantified definitions of incidence and prevalence. (Source: Gastroenterology)
Source: Gastroenterology - January 25, 2024 Category: Gastroenterology Authors: Lindsay Hracs, Joseph Windsor, Julia Gorospe, Michael Buie, Joshua Quan, Lea Caplan, Ante Markovinovic, Michael Cummings, Quinn Goddard, Tyler Williamson, Yvonne Abbey, Maria Abreu, Raja Ali, Murdani Abdullah, Mansour Altuwaijri, Vineet Ahuja, Domingo Bal Source Type: research
Modeling the transition to the fourth epidemiologic stage of inflammatory bowel disease: prevalence equilibrium
A theoretical framework for population-level transition across four epidemiologic stages has been proposed for inflammatory bowel disease (IBD): 1. Emergence (low incidence/prevalence); 2. Acceleration in Incidence (rapid rising incidence); 3. Compounding Prevalence (stabilizing incidence, rapid rising prevalence); and 4. Prevalence Equilibrium (decelerated prevalence), which no region has entered yet. Many regions of the early-industrialized world (North America, Europe, Oceania) are currently in stage 3. (Source: Gastroenterology)
Source: Gastroenterology - January 25, 2024 Category: Gastroenterology Authors: Joseph Windsor, Lindsay Hracs, Michael Cummings, Julia Gorospe, Michael Buie, Joshua Quan, Ante Markovinovic, Lea Caplan, Quinn Goddard, Tyler Williamson, Yvonne Abbey, Maria Abreu, Raja Ali, Murdani Abdullah, Mansour Altuwaijri, Vineet Ahuja, Domingo Bal Source Type: research
Mortality in inflammatory bowel disease: a longitudinal population-based study in the united states
Inflammatory bowel diseases (IBD) are chronic inflammatory disorders of the gastrointestinal tract. Data are limited regarding how longevity in IBD compares to the general population. The aim of this study was to compare the mean age of death and causes of mortality between patients with IBD and the general population in a nationally representative cohort. (Source: Gastroenterology)
Source: Gastroenterology - January 25, 2024 Category: Gastroenterology Authors: Laura Maas, Andrew Weber, Jenny Sauk, Alyssa Parian, Berkeley Limketkai Source Type: research
Patients with crohn's disease affected by non-alcoholic fatty liver disease have a greater risk of mortality and worse clinical outcomes
Crohn's disease (CD) has a high prevalence rate and it affects millions of patients worldwide. Non-Alcoholic Fatty Liver Disease (NAFLD) is an emerging disease predisposing to adverse outcomes. There is limited evidence of clinical outcomes of NAFLD in patients with CD. We sought to investigate this population. (Source: Gastroenterology)
Source: Gastroenterology - January 25, 2024 Category: Gastroenterology Authors: Kenan Rahima, Mhd Kutaiba Albuni, Mohamad Hijazi, Tochukwu Ikpeze, Bassel Bitar, Venkata Muddana Source Type: research
Patients with ulcerative colitis affected by non-alcoholic fatty liver disease have a greater risk of mortality and worse clinical outcomes
Ulcerative colitis (UC) affects millions of patients worldwide and keeps trending upward. Non-Alcoholic Fatty Liver Disease (NAFLD) is an emerging disease predisposing to adverse outcomes. There is limited evidence of clinical outcomes of NAFLD in patients with UC. We sought to investigate this population. (Source: Gastroenterology)
Source: Gastroenterology - January 25, 2024 Category: Gastroenterology Authors: Kenan Rahima, Leonid Khokhlov, Mhd Kutaiba Albuni, Mohamad Hijazi, Tochukwu Ikpeze, Venkata Muddana Source Type: research
Persistence while on labeled maintenance dose among advanced therapy-experienced patients with ulcerative colitis initiated on ustekinumab or adalimumab
This study compared persistence while on labeled maintenance dose among ADT-experienced patients with UC initiated on ustekinumab or adalimumab. (Source: Gastroenterology)
Source: Gastroenterology - January 25, 2024 Category: Gastroenterology Authors: Porpong Boonmak, Sumesh Kachroo, Maryia Zhdanava, Sabree Burbage, Aditi Shah, Jill Korsiak, Patrick Lefebvre, Caroline Kerner, Dominic Pilon Source Type: research
Persistence while on labeled maintenance dose among advanced therapy-na Ïve patients with ulcerative colitis initiated on ustekinumab or adalimumab
This study compared treatment persistence while on labeled maintenance dose among advanced therapy (ADT)-na ïve patients with UC on ustekinumab or adalimumab. (Source: Gastroenterology)
Source: Gastroenterology - January 25, 2024 Category: Gastroenterology Authors: Sumesh Kachroo, Maryia Zhdanava, Sabree Burbage, Porpong Boonmak, Aditi Shah, Jill Korsiak, Patrick Lefebvre, Caroline Kerner, Dominic Pilon Source Type: research
Real-world long-term treatment persistence among bio-na Ïve patients with crohn’s disease and history of fistula initiated on ustekinumab
This study described long-term persistence among bio-naïve patients with CD and history of fistula who were initiated on ustekinumab (anti-interleukin 12/23 antibody). (Source: Gastroenterology)
Source: Gastroenterology - January 25, 2024 Category: Gastroenterology Authors: Maryia Zhdanava, Sumesh Kachroo, Porpong Boonmak, Sabree Burbage, Aditi Shah, Zhuohan Jiang, Patrick Lefebvre, Caroline Kerner, Dominic Pilon Source Type: research
Real-world treatment persistence among advanced therapy-experienced patients with ulcerative colitis initiated on ustekinumab or adalimumab
This study compared persistence among ADT-experienced patients with UC initiated on ustekinumab (anti-interleukin 12/23 antibody), or adalimumab (anti-tumor necrosis factor biologic). (Source: Gastroenterology)
Source: Gastroenterology - January 25, 2024 Category: Gastroenterology Authors: Maryia Zhdanava, Sumesh Kachroo, Porpong Boonmak, Sabree Burbage, Aditi Shah, Jill Korsiak, Patrick Lefebvre, Caroline Kerner, Dominic Pilon Source Type: research
