AGA Clinical Practice Update on Diagnosis and Management of Cannabinoid Hyperemesis Syndrome: Commentary
The purpose of this American Gastroenterological Association (AGA) Institute Clinical Practice Update (CPU) is to review the available evidence and provide expert advice regarding diagnosis and management of cannabinoid hyperemesis syndrome. (Source: Gastroenterology)
Source: Gastroenterology - March 5, 2024 Category: Gastroenterology Authors: Alberto Rubio-Tapia, Richard McCallum, Michael Camilleri Tags: Clinical Practice Update Source Type: research

Colorectal tumor recurrence on a mysterious spot
(Source: Gastroenterology)
Source: Gastroenterology - March 5, 2024 Category: Gastroenterology Authors: D.A. Verhoeven, A.S.L.P. Crobach, J.J. Boonstra Tags: Electronic Gastro Curbside Consult Source Type: research

Sacral neural crest-independent origin of the enteric nervous system in mouse
The enteric nervous system (ENS), the gut ’s intrinsic nervous system critical for gastrointestinal function and gut-brain communication, is believed to mainly originate from vagal neural crest cells (vNCCs) and partially from sacral NCCs (sNCCs). Resolving the exact origins of the ENS is critical for understanding congenital ENS diseases but has been confounded by the inability to distinguish between both NCC populations in situ. Here, we aimed to resolve the exact origins of the mammalian ENS. (Source: Gastroenterology)
Source: Gastroenterology - March 5, 2024 Category: Gastroenterology Authors: Qi Yu, Li Liu, Mengjie Du, Daniel M üller, Yan Gu, Zhigang Gao, Xiaolong Xin, Yanlan Gu, Miao He, Till Marquardt, Liang Wang Tags: Basic and Translational - Alimentary Tract Source Type: research

A colorful conundrum: dark urine in a patient with inflammatory bowel disease
(Source: Gastroenterology)
Source: Gastroenterology - March 4, 2024 Category: Gastroenterology Authors: Stefan Mitev, Cvetelina Marinova, Zoya Spassova Tags: Electronic Gastro Curbside Consult Source Type: research

Single-Use vs Reusable Duodenoscopes: How Infection Knowledge Gaps Are Driving Environmental Harm and What Can Be Done
More than 500,000 duodenoscopies are now performed annually in the United States.1 Increased reports of duodenoscope-associated infections (DAIs) after endoscopic retrograde cholangiopancreatography (ERCP) over the past decade have sparked discussions about how to reduce the incidence of DAIs and have propelled the adoption of single-use duodenoscopes (SUDs) as an infection mitigation strategy. Meanwhile, potential downsides to SUDs, including increased environmental and public health impacts, costs, and supply chain risks, also warrant discussion, especially because the true benefits of these devices remain unclear. (Sour...
Source: Gastroenterology - March 3, 2024 Category: Gastroenterology Authors: Matthew W. Smith, Lyndon V. Hernandez, Pamela Lee, Richard A. Martinello, Hardeep Singh, Jodi D. Sherman Tags: Commentary Source Type: research

Incidence and prediction of unrelated mortality after successful endoscopic eradication therapy for Barrett ’s neoplasia.
Follow-up (FU) strategies after endoscopic eradication therapy (EET) for Barrett ’s neoplasia do not consider the risk of mortality from other causes than esophageal adenocarcinoma (EAC). We aimed to evaluate this risk during long-term FU, and to assess whether the Charlson Comorbidity Index (CCI) can predict mortality. (Source: Gastroenterology)
Source: Gastroenterology - March 3, 2024 Category: Gastroenterology Authors: Sanne.N. van Munster, Eva P.D. Verheij, Özge Ozdemir, Esther Toes-Zoutendijk, Iris Lansdorp-Vogelaar, Esther A. Nieuwenhuis, Cary C. Cotton, Bas L.A. M. Weusten, Lorenza Alvarez Herrero, Alaa Alkhalaf, B. Ed Schenk, Erik J. Schoon, Wouter L. Curvers, Arj Tags: Clinical - Alimentary Tract Source Type: research

Single-Use vs. Reusable Duodenoscopes: How Infection Knowledge Gaps Are Driving Environmental Harm and What Can Be Done
(Source: Gastroenterology)
Source: Gastroenterology - March 3, 2024 Category: Gastroenterology Authors: Matthew W. Smith, Lyndon V. Hernandez, Pamela Lee, Richard A. Martinello, Hardeep Singh, Jodi D. Sherman Tags: Commentary Source Type: research

Diagnosis and Management of Pancreatic Cysts
(Source: Gastroenterology)
Source: Gastroenterology - March 3, 2024 Category: Gastroenterology Authors: Timothy B. Gardner, Walter G. Park, Peter J. Allen Tags: Reviews in Basic and Clinical Gastroenterology and Hepatology Source Type: research

Prevalence of Sessile Serrated Lesions in Individuals With Positive Fecal Immunochemical Test Result Undergoing Colonoscopy: Results From a Large Nationwide Veterans Affairs Database
Sessile serrated lesions (SSLs) are important precursors to colorectal cancer (CRC). It is estimated that 20% to 30% of CRCs arise from SSLs through a pathway distinct from the traditional adenoma-carcinoma sequence. The US Multi-Society Task Force on CRC recommends colonoscopy or fecal immunochemical test (FIT) as tier 1 tests for CRC screening in average-risk individuals.1 (Source: Gastroenterology)
Source: Gastroenterology - February 29, 2024 Category: Gastroenterology Authors: Natalie Wilson, Mohammad Bilal, Anders Westanmo, Amy Gravely, Aasma Shaukat Tags: Research Letters Source Type: research

Reply
We read with interest the letter from Vege et  al1 about our recent population-based cohort study describing the natural history of inflammatory pancreatic diseases using a multistate disease model.2 We fully agree that one of the key observations of our study is the finding that more than one-half of patients with chronic pancreatitis have no previous history of acute pancreatitis. This is an important finding because it challenges the sentinel acute pancreatitis event (SAPE) hypothesis, a prevailing theory regarding the progression of inflammatory pancreatic diseases. (Source: Gastroenterology)
Source: Gastroenterology - February 29, 2024 Category: Gastroenterology Authors: Mathias Ellgaard Cook, S øren Schou Olesen, Niels Henrik Bruun Tags: Correspondence Source Type: research

Bridging the Diagnostic Gap: How Autonomous Artificial Intelligence Can Assist in Endoscopic Diagnosis of Experts
I read with interest the article by Djinbachian et  al1 comparing autonomous artificial intelligence (AI) with AI-assisted human optical diagnosis of colorectal polyps. It is an important contribution, and additional perspectives regarding implementation into clinical practice deserve discussion. (Source: Gastroenterology)
Source: Gastroenterology - February 29, 2024 Category: Gastroenterology Authors: Hantong Hu Tags: Correspondence Source Type: research

Lessons From Japan ’s Case for Early Helicobacter pylori Screening
The review by Moss et  al1 recently published in Gastroenterology is highly valuable as it comprehensively summarizes recent management approaches for Helicobacter pylori infection. Despite its strengths, this review could benefit from an expanded discussion of several under-addressed areas to deepen the readers’ unde rstanding of H pylori management strategies. (Source: Gastroenterology)
Source: Gastroenterology - February 29, 2024 Category: Gastroenterology Authors: Taiga Uchiyama, Hiroaki Saito, Yoshitaka Nishikawa Tags: Correspondence Source Type: research

Ferroptosis: Biology and Role in Gastrointestinal Disease
Ferroptosis is a form of nonapoptotic cell death that involves iron-dependent phospholipid peroxidation induced by accumulation of reactive oxygen species (ROS), and results in plasma membrane damage and the release of damage-associated molecular patterns. Ferroptosis has been implicated in aging and immunity, as well as disease states including intestinal and liver conditions and cancer. To date, several ferroptosis-associated genes and pathways have been implicated in liver disease. While ferroptotic cell death is associated with dysfunction of the intestinal epithelium, the underlying molecular basis is poorly understoo...
Source: Gastroenterology - February 29, 2024 Category: Gastroenterology Authors: J.J. Escuder-Rodr íguez, D. Liang, X. Jiang, F.A. Sinicrope Tags: Reviews in Basic and Clinical Gastroenterology and Hepatology Source Type: research

Prevalence of Sessile Serrated Lesions in Individuals with Positive Fecal Immunochemical Test Undergoing Colonoscopy: Results from a Large Nationwide Veterans Affairs Database
(Source: Gastroenterology)
Source: Gastroenterology - February 29, 2024 Category: Gastroenterology Authors: Natalie Wilson, Mohammad Bilal, Anders Westanmo, Amy Gravely, Aasma Shaukat Tags: Research Letter Source Type: research

Lessons from Japan's Case for Early Helicobacter pylori Screening
(Source: Gastroenterology)
Source: Gastroenterology - February 29, 2024 Category: Gastroenterology Authors: Taiga Uchiyama, Hiroaki Saito, Yoshitaka Nishikawa Tags: Correspondence Source Type: research