Unlocking the potential of fecal virome transplants (FVT): modulating the gut-brain axis in stress-related disorders
(Source: Gastroenterology)
Source: Gastroenterology - April 15, 2024 Category: Gastroenterology Authors: Chalystha Yie Qin Lee, Kara Gross Margolis Tags: Gastro Digest Source Type: research

An Unusual Cause of Cat Scratch Colon
(Source: Gastroenterology)
Source: Gastroenterology - April 15, 2024 Category: Gastroenterology Authors: Xiao Yan Ye, Yue Guan, Jie Yuan Tags: Electronic Gastro Curbside Consult Source Type: research

GLP1 receptor agonists and post-endoscopic aspiration pneumonia: what plays a role in clinical practice?
(Source: Gastroenterology)
Source: Gastroenterology - April 15, 2024 Category: Gastroenterology Authors: Hui Xu, Lianjun Lin Tags: Correspondence Source Type: research

Microbial metabolite: a link between psychological stress and epithelial disturbance
(Source: Gastroenterology)
Source: Gastroenterology - April 10, 2024 Category: Gastroenterology Authors: David Reed Tags: Gastro Digest Source Type: research

How Future Pharmacologic Therapies for Celiac Disease Will Complement the Gluten-Free Diet
The only proven treatment for celiac disease is adherence to a strict, lifelong, gluten-free diet. However, complete dietary gluten avoidance is challenging and a substantial number of patients do not respond fully, clinically, or histologically, despite their best efforts. As celiac disease is common and its central pathophysiology is well elucidated, it has become attractive for drug development to address the limitations of dietary treatment. Most efforts address nonresponsive celiac disease, defined as continued symptoms and/or signs of disease activity despite a gluten-free diet, including the more severe forms of ref...
Source: Gastroenterology - April 9, 2024 Category: Gastroenterology Authors: Valentina Discepolo, Ciar án P. Kelly, Frits Koning, Detlef Schuppan Tags: Invited 2024 13th Issue: Celiac Disease Source Type: research

Intestinal inflammation and extraintestinal disease: understanding dynamic risk
(Source: Gastroenterology)
Source: Gastroenterology - April 9, 2024 Category: Gastroenterology Authors: James J. Ashton, Jack Satsangi, Holm H. Uhlig Tags: Editorials Source Type: research

How future pharmacological therapies for celiac disease will complement the gluten-free diet
The only proven treatment for celiac disease is adherence to a strict, lifelong, gluten free diet. However, complete dietary gluten avoidance is challenging and a substantial number of patients do not respond fully, clinically or histologically, despite their best efforts. As celiac disease is common and its central pathophysiology is well elucidated, it has become attractive for drug development to address the limitations of dietary treatment. Most efforts address non-responsive celiac disease, defined as continued symptoms and/or signs of disease activity despite a gluten free diet, including the more severe forms of ref...
Source: Gastroenterology - April 9, 2024 Category: Gastroenterology Authors: Valentina Discepolo, Ciar án P. Kelly, Frits Koning, Detlef Schuppan Tags: Invited 2024 13th Issue: Celiac Disease Source Type: research

Nutrition Assessment and Management in Celiac Disease
Celiac disease (CeD) is the most common immune condition affecting the gastrointestinal tract; it is triggered by gluten and the only available treatment is a strict gluten-free diet (GFD). Therefore, for patients with CeD, adopting a GFD is not a lifestyle choice. The major problem is that a GFD is restrictive and, like all restrictive diets, it has the potential for adverse nutritional outcomes, especially if adopted for a long term. It is well known that GFD can be nutritionally inadequate and is frequently associated with vitamin and mineral deficiencies; it is also associated with excessive sugar and fat intake, parti...
Source: Gastroenterology - April 6, 2024 Category: Gastroenterology Authors: M. Ines Pinto-Sanchez, Jedid-Jah Blom, Peter R. Gibson, David Armstrong Tags: Invited 2024 13th Issue: Celiac Disease Source Type: research

Nutrition assessment and management in celiac disease.
CeD is the most common immune condition affecting the gastrointestinal tract; it is triggered by gluten and the only available treatment is a strict gluten-free diet (GFD). Therefore, for patients with CeD, adopting a GFD is not a lifestyle choice. The major problem is that a GFD is restrictive, and like all restrictive diets, it has the potential for adverse nutritional outcomes, especially if adopted for a long-term. It is well known that GFD can be nutritionally inadequate and is frequently associated with vitamin and mineral deficiencies; it is, also, associated with excessive sugar and fat intake, particularly when gl...
Source: Gastroenterology - April 6, 2024 Category: Gastroenterology Authors: M Ines Pinto-Sanchez, Jedid-Jah Blom, Peter R. Gibson, David Armstrong Tags: Invited 2024 13th Issue: Celiac Disease Source Type: research

Intestinal motility may not be completely dependent on epithelial Ret signalling in the adult intestine
(Source: Gastroenterology)
Source: Gastroenterology - April 6, 2024 Category: Gastroenterology Authors: Faidra Karkala, Min Wang, Maria M. Alves, Kaushal Parikh Tags: Correspondence Source Type: research

Impaired glycosylation of gastric mucins drives gastric tumorigenesis and serves as a novel therapeutic target.
Gastric cancer is often accompanied by a loss of MUC6, but its pathogenic role in gastric carcinogenesis remains unclear. (Source: Gastroenterology)
Source: Gastroenterology - April 5, 2024 Category: Gastroenterology Authors: Junya Arai, Yoku Hayakawa, Hiroaki Tateno, Keita Murakami, Takeru Hayashi, Masahiro Hata, Yuki Matsushita, Hiroto Kinoshita, Sohei Abe, Ken Kurokawa, Yukiko Oya, Mayo Tsuboi, Sozaburo Ihara, Ryota Niikura, Nobumi Suzuki, Yusuke Iwata, Toshiro Shiokawa, Ch Tags: Basic and Translational - Alimentary Tract Source Type: research

Rapid Endoscopic Diagnosis of Benign Ulcerative Colorectal Diseases with an Artificial Intelligence Contextual Framework
Benign ulcerative colorectal diseases (UCDs) such as ulcerative colitis (UC), Crohn ’s disease (CD), ischemic colitis (IC) and intestinal tuberculosis (ITB) share similar phenotypes with different etiologies and treatment strategies. To accurately diagnose closely-related diseases like UCDs, we hypothesize that contextual learning is critical in enhancing the ability of the artif icial intelligence models to differentiate the subtle differences in lesions amidst the vastly divergent spatial contexts. (Source: Gastroenterology)
Source: Gastroenterology - April 4, 2024 Category: Gastroenterology Authors: Xiaobei Luo, Jiahao Wang, Chuanchuan Tan, Qi Dou, Zelong Han, Zhenjiang Wang, Farah Tasnim, Xiyu Wang, Qiang Zhan, Xiang Li, Qunyan Zhou, Jianbin Cheng, Fabiao Liao, Hon Chi Yip, Jiayi Jiang, Robby T. Tan, Side Liu, Hanry Yu Tags: Clinical - Alimentary Tract Source Type: research

Comparison of Vonoprazan versus Intravenous Proton Pump Inhibitor for Prevention of High-Risk Peptic Ulcers Rebleeding after Successful Endoscopic Hemostasis: A Multicenter Randomized Noninferiority Trial
This study aims to compare the efficacy of vonoprazan versus PPI for preventing high-risk PU rebleeding after hemostasis. (Source: Gastroenterology)
Source: Gastroenterology - April 4, 2024 Category: Gastroenterology Authors: Tanawat Geeratragool, Uayporn Kaosombatwattana, Arpapun Boonchote, Suvikrom Chatthammanat, Nutchanun Preechakawin, Jompol Srichot, Asawin Sudcharoen, Pavapol Sirisunhirun, Panotpol Termsinsuk, Manus Rugivarodom, Julajak Limsrivilai, Monthira Maneerattanap Tags: Clinical - Alimentary Tract Source Type: research

An Immunocompetent Mongolian Gerbil Model for Hepatitis E Virus Genotype 1 Infection
Hepatitis E virus (HEV), primarily genotype 1 (HEV-1), causes approximately 20.1 million infections, 44000 deaths, and 3000 stillbirths annually. Current evidence indicates that HEV-1 is only transmitted in humans. Here, we evaluated whether Mongolian gerbils can serve as animal models for HEV-1 infection. (Source: Gastroenterology)
Source: Gastroenterology - April 4, 2024 Category: Gastroenterology Authors: Tianxu Liu, Qiyu He, Xinyue Yang, Yuebao Li, Disen Yuan, Qinghui Lu, Tianyu Tang, Guiwe Guan, Liwei Zheng, He Zhang, Changyou Xia, Xin Yin, Guochao Wei, Xiangmei Chen, Fengmin Lu, Lin Wang Tags: Basic and Translational - Liver Source Type: research

Reply to Metoki et al, Shiratori et al, and Li et al
(Source: Gastroenterology)
Source: Gastroenterology - April 4, 2024 Category: Gastroenterology Authors: Hae Won Yoo, Su Jin Hong Tags: Correspondence Source Type: research