European Journal of Gastroenterology and Hepatology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Novel predictors for liver transplantation or death in drug-induced acute liver failure
Conclusion While baseline MELD score, INR, CHE, and platelet counts had limited potential to discriminate between DI-ALF with survival or poor outcome, their combinations were highly associated with OLT or death in patients with DI-ALF. (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - March 3, 2022 Category: Gastroenterology Tags: Original Articles: Hepatology Source Type: research

Selective internal radiation therapy in older patients with hepatocellular carcinoma: a retrospective analysis
Conclusion SIRT appears to be a well-tolerated treatment with the same efficacy in elderly compared to younger patients in HCC. Our study is the first to study its impact with glass microspheres. This warrants confirmation in large prospective studies. (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - March 3, 2022 Category: Gastroenterology Tags: Original Articles: Hepatology Source Type: research

Simplified 6-month prediction scores for primary biliary cholangitis patients treated with ursodeoxycholic acid
Objectives To develop a prognostic score evaluating treatment response at 6 months after ursodeoxycholic acid (UDCA) initiation in primary biliary cholangitis (PBC) patients. Methods Adult PBC patients who were newly prescribed UDCA at our institution (n = 292) were included. Significant determinants of liver-related adverse events in the multivariable Cox model were used for score development, weighted by β-coefficients. Discrimination ability was assessed using Harrell’s C-statistic. The performance of our model was compared to the previous models. Results Our model included the following varia...
Source: European Journal of Gastroenterology and Hepatology - March 3, 2022 Category: Gastroenterology Tags: Original Articles: Hepatology Source Type: research

Colorectal cancer screening by fecal immunochemical test or colonoscopy in France: how many people are actually covered? Focus on the Provence-Alpes-Côte d’Azur region
Background Colorectal cancer (CRC) screening with fecal immunochemical test (FIT) remains low in France, particularly in the Provence-Alpes-Côte-d’Azur (PACA) region. The aim of this study was to compare insured persons (50–74 years) who had FIT and/or colonoscopy in PACA with the general French population. Methods FIT and colonoscopy rates were calculated according to SP-France and National Health Data System data. Results The rate of FIT in 2016–2017 was lower in PACA than in France (25.6 vs. 29.1%, P (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - March 3, 2022 Category: Gastroenterology Tags: Original Articles: Gastroenterology Source Type: research

French experience with telemedicine in inflammatory bowel disease: a patients and physicians survey
Conclusion Patients and gastroenterologists were satisfied with telemedicine and would be willing to use it in the future. However, telemedicine does not replace in-person visits and should be discussed on a case-by-case basis. (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - March 3, 2022 Category: Gastroenterology Tags: Original Articles: Gastroenterology Source Type: research

Clinical characteristics and prognostic factors for Crohn’s disease relapses using natural language processing and machine learning: a pilot study
Conclusion Through NLP, we identified variables such as smoking as a risk factor and described treatment patterns with biologics in CD patients. CD relapse prediction highlighted the importance of patients’ age and some biochemistry values, though it proved highly challenging and merits the assessment of risk factors for relapse in a clinical setting. (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - March 3, 2022 Category: Gastroenterology Tags: Original Articles: Gastroenterology Source Type: research

Therapeutic drug monitoring in Crohn’s disease patients treated with anti-TNF: a comparison of two techniques
In this study we aimed to evaluate the capability of POC to discriminate between relapse and remission disease phases, and to assess the concordance of the POC and homogeneous mobility shift assay (HMSA) results. Methods Drug trough level of 46 Crohn’s disease patients treated with either adalimumab or infliximab were evaluated with both a POC technique and an HMSA at various time points (week-16 and -48) during anti-TNF treatment. Results Median adalimumab trough level of patients in remission were significantly higher as compared to relapsing patients using both HMSA (week 16, P = 0.0001; week48, P ...
Source: European Journal of Gastroenterology and Hepatology - March 3, 2022 Category: Gastroenterology Tags: Original Articles: Gastroenterology Source Type: research

Efficacy and safety of endoscopic resection techniques of large colorectal lesions: experience of a referral center in Italy
Conclusions EPMR, ESD and H-ESD are effective and safe procedures. Recurrence rate in EPMR was higher but can be managed endoscopically with high success rates. EPMR is faster and technically simpler so should be considered a potential first-line therapy for colorectal superficial neoplastic lesions. (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - March 3, 2022 Category: Gastroenterology Tags: Original Articles: Gastroenterology Source Type: research

Dual biologic therapy with Vedolizumab and Ustekinumab for refractory Crohn’s disease in children
We report the use of dual biologic therapy with vedolizumab and ustekinumab for three highly refractory patients who previously failed both of these medications as monotherapy. The dual biologic therapy led to the closure of a recto-vaginal fistula and restoration of continuity after takedown of a stoma. (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - March 3, 2022 Category: Gastroenterology Tags: Original Articles: Gastroenterology Source Type: research

Nonalcoholic fatty liver disease and risk of incident hypertension: a systematic review and meta-analysis
The objective of this systematic review and meta-analysis was to obtain a precise and reliable estimate of the nature and magnitude of this association. We systematically searched Ovid-MEDLINE up to March 2021 for observational studies in which NAFLD was diagnosed in adults using blood-based panels, imaging techniques or liver biopsy and with a follow-up ≥1 year. Measures of association from individual studies were meta-analyzed using random-effects models. Of the 1108 titles initially scrutinized, we included 11 cohort studies with data on 390 348 participants (52% male) and a mean follow-up of 5.7 years. In the o...
Source: European Journal of Gastroenterology and Hepatology - March 3, 2022 Category: Gastroenterology Tags: Review Article Source Type: research

Paper alert
No abstract available (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - February 1, 2022 Category: Gastroenterology Tags: Paper Alert Source Type: research

Hyperbaric oxygen therapy in inflammatory bowel disease: a systemic review and meta-analysis
No abstract available (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - February 1, 2022 Category: Gastroenterology Tags: Letters to the Editor Source Type: research

The prognostic information of acute kidney injury in patients with decompensated cirrhosis
No abstract available (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - February 1, 2022 Category: Gastroenterology Tags: Letters to the Editor Source Type: research

Eosinophilic gastritis within gastric heterotopia of Meckel’s diverticulum
No abstract available (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - February 1, 2022 Category: Gastroenterology Tags: Letters to the Editor Source Type: research

Cryoballoon ablation as salvage therapy after nonradical resection of a high-risk T1b esophageal adenocarcinoma: a case report
We report the first case in which cryoballoon ablation was successfully performed as salvage therapy with a curative intent for positive deep resection margins after an incomplete endoscopic resection of a recurrent early esophageal adenocarcinoma. (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - February 1, 2022 Category: Gastroenterology Tags: Case report Source Type: research