European Journal of Gastroenterology and Hepatology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Colonic mucosal eosinophilia and immunohistochemical expression of COX-2 and NF-kB in patients with irritable bowel syndrome
Conclusion Patients with IBS -particularly IBS-D subtype- should undergo colonoscopy and biopsy to exclude underlying inflammatory pathology. Moreover, patients with positive COX-2 and NF-kB need further evaluation and follow-up. (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - April 21, 2022 Category: Gastroenterology Tags: Original Articles: Gastroenterology Source Type: research

Somatosensory assessments in patients with inflammatory bowel disease: a cross-sectional study examining pain processing pathways and the role of multiple patient factors
Background Pain affects the majority of patients with inflammatory bowel disease (IBD), where pain experiences may be influenced by multiple patient factors and changes within central pain processing pathways, termed central sensitization. The current study aimed to investigate pain processing pathways in patients with IBD through somatosensory testing and associations with multiple patient factors. Methods A cross-sectional study of adults with IBD. Assessments included: somatosensory tests [i.e. pressure pain thresholds (PPT), temporal summation (TS), conditioned pain modulation (CPM)], and patient factors (i....
Source: European Journal of Gastroenterology and Hepatology - April 21, 2022 Category: Gastroenterology Tags: Original Articles: Gastroenterology Source Type: research

Randomized control trial on the efficacy of Limosilactobacillus reuteri ATCC PTA 4659 in reducing inflammatory markers in acute uncomplicated diverticulitis
Introduction Recent guidelines suggest treating acute uncomplicated diverticulitis (AUD) without antibiotics. We tested the efficacy of Limosilactobacillus reuteri ATCC PTA 4659 in AUD. Primary outcome was the reduction of abdominal pain and inflammatory markers [C-reactive protein (C-RP) and calprotectin]. Secondary outcome was the reduction of hours of hospitalization. Patients and methods A double-blind, randomized controlled trial was conducted in 119 patients with AUD. The probiotic group (61 patients) was treated with fluids, bowel rest and L. reuteri/b.i.d. for 10 days. The placebo group (58 patients) was...
Source: European Journal of Gastroenterology and Hepatology - April 21, 2022 Category: Gastroenterology Tags: Original Articles: Gastroenterology Source Type: research

De-escalation of biological therapy in inflammatory bowel disease patients following prior dose escalation
Conclusion De-escalation after biological dose escalation was successful in the majority of carefully selected IBD patients. Objective assessment of remission increased the likelihood of successful de-escalation. (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - April 21, 2022 Category: Gastroenterology Tags: Original Articles: Gastroenterology Source Type: research

Metal versus plastic stents in the management of benign biliary strictures: systematic review and meta-analysis of randomized controlled trials
Benign biliary strictures (BBS) are usually treated with endoscopic retrograde cholangiopancreatography (ERCP) with the placement of multiple plastic stents (MPS) or a covered self-expandable metal stent (CSEMS). In this meta-analysis, we compared the efficacy and safety of MPS and CSEMS in the management of BBS. We reviewed several databases from inception to 28 April 2021 to identify RCTs that compared MPS with CSEMS in the management of BBS. Our outcomes of interest were stricture resolution, stricture recurrence, adverse events, stent migration and mean number of ERCPs to achieve stricture resolution. Data were analyze...
Source: European Journal of Gastroenterology and Hepatology - April 21, 2022 Category: Gastroenterology Tags: Reviews article Source Type: research

NMDA and AMPA receptor physiology and role in visceral hypersensitivity: a review
In this study, we review the updated findings on the physiology of NMDARs and AMPARs and their relation to visceral hypersensitivity, which propose directions for future research in this field with evolving importance. (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - April 21, 2022 Category: Gastroenterology Tags: Reviews article Source Type: research

Paper alert
No abstract available (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - March 3, 2022 Category: Gastroenterology Tags: Paper Alert Source Type: research

A magnet for extraction of metal foreign body within food bolus
No abstract available (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - March 3, 2022 Category: Gastroenterology Tags: Letters to the Editor Source Type: research

Comment on ‘Characterizing a cohort of Egyptian patients with acute-on-chronic liver failure’
No abstract available (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - March 3, 2022 Category: Gastroenterology Tags: Letters to the Editor Source Type: research

Rectal hematoma caused by colon rupture in a COVID-19 patient: a dreaded complication of infection
No abstract available (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - March 3, 2022 Category: Gastroenterology Tags: Letters to the Editor Source Type: research

Acute liver injury following methylprednisolone pulse therapy: 13 cases from a prospectively collected cohort
Discussion MPS-related liver injury can be life-threatening, occurs with considerable latency and after repeat dosing. Regular surveillance of hepatic biochemistry should therefore be routinely performed also after discharge to avoid further MPS-related liver injury during repeat application. Swift response to prednisolone but not histologic features can be helpful to discriminate MPS-DILI from AIH. (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - March 3, 2022 Category: Gastroenterology Tags: Original Articles: Hepatology Source Type: research

Predictors of survival in portopulmonary hypertension: a 20-year experience
Conclusion PoPH patients have poor 5-year survival which is strongly associated to the severity of underlying liver disease and not to the hemodynamic severity of PoPH; therefore efforts should be focused in facilitating liver transplantation for these patients. (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - March 3, 2022 Category: Gastroenterology Tags: Original Articles: Hepatology Source Type: research

Serum copper, ceruloplasmin, and their relations to metabolic factors in nonalcoholic fatty liver disease: a cross-sectional study
This study aimed to investigate serum copper (Cu) and ceruloplasmin (Cer) levels and their relations to metabolic factors in NAFLD. Methods This cross-sectional study was conducted on 141 subjects with NAFLD diagnosed using abdominal ultrasonography. Personal information, anthropometric measures, glucose and lipid profile, and serum levels of liver enzymes were assessed. Fasting serum levels of Cu and Cer were determined using colorimetry and nephelometry assay, respectively. Odds ratios (ORs) were used to examine the associations of serum Cu and Cer levels with NAFLD risk. Results The results on 85 patients ...
Source: European Journal of Gastroenterology and Hepatology - March 3, 2022 Category: Gastroenterology Tags: Original Articles: Hepatology Source Type: research

Prognostic value of neutrophil-to-lymphocyte ratio in cirrhosis patients undergoing transjugular intrahepatic portosystemic shunt
Conclusion Our data indicate that elevated NLR independently predicts 30-day and 90-day mortality. In patients with a MELD ≤ 15, NLR is a better prognostic factor than MELD or MELD-Na in predicting short-term mortality. (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - March 3, 2022 Category: Gastroenterology Tags: Original Articles: Hepatology Source Type: research

Healthcare practitioners’ diagnostic and treatment practice patterns of nonalcoholic fatty liver disease in Poland: a cross-sectional survey
Conclusions NAFLD is not a silent disease as physicians and patients reported many, albeit nonspecific, symptoms. This cross-sectional survey provides important insights into clinical management of NAFLD by GEs and GPs in Poland. (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - March 3, 2022 Category: Gastroenterology Tags: Original Articles: Hepatology Source Type: research