Paper alert
No abstract available (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - June 3, 2020 Category: Gastroenterology Tags: Paper Alerts Source Type: research

No part of the colon is immune from large Bilharzial polyps
No abstract available (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - June 3, 2020 Category: Gastroenterology Tags: Letters to the Editor Source Type: research

Giant fibrovascular polyp of the esophagus with intermittent airway obstruction
No abstract available (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - June 3, 2020 Category: Gastroenterology Tags: Letters to the Editor Source Type: research

Immune checkpoint inhibitors-induced acute diverticulitis
No abstract available (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - June 3, 2020 Category: Gastroenterology Tags: Letters to the Editor Source Type: research

Management of type II endoscopic retrograde cholangiopancreatography-related perforations by placement of multiple plastic stents
No abstract available (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - June 3, 2020 Category: Gastroenterology Tags: Letters to the Editor Source Type: research

Pyostomatitis vegetans in a pediatric patient with ulcerative colitis: case report of a rare pediatric inflammatory bowel disease extraintestinal manifestation and review of the literature
We report the case of a 9-year-old female patient affected by ulcerative colitis and recently treated for an oral candidiasis, who experienced a relapse in her ulcerative colitis (PUCAI 50), preceded by the return of whitish lesions in the oral cavity, initially misdiagnosed and unsuccessfully treated as candidiasis and then recognized as pyostomatitis vegetans. Bloody diarrhea was treated with oral beclomethasone, with rapid remission of ulcerative colitis and disappearance of pyostomatitis vegetans. After 2 years, ulcerative colitis is in sustained remission with oral mesalamine and pyostomatitis vegetans has not recurre...
Source: European Journal of Gastroenterology and Hepatology - June 3, 2020 Category: Gastroenterology Tags: Case Report Source Type: research

External validation of the Toronto hepatocellular carcinoma risk index in Turkish cirrhotic patients
Objectives: Toronto hepatocellular carcinoma risk index is developed to stratify cirrhotic patients according to 10-year hepatocellular carcinoma risk. We aimed to validate the performance of Toronto hepatocellular carcinoma risk index in a large Turkish cohort. Materials and methods: We retrospectively reviewed the database of 1287 cirrhotic patients followed-up in a 10-year period (February 2008 to January 2018). All patients were stratified into three groups based on the Toronto hepatocellular carcinoma risk index score as follows: low-risk, 240. Area under the curve and optimal cutoff value of Toronto hepatocellul...
Source: European Journal of Gastroenterology and Hepatology - June 3, 2020 Category: Gastroenterology Tags: Original Articles: Hepatology Source Type: research

Early detection of hepatocellular carcinoma in patients with diabetes mellitus
Conclusion FIB4A is a potential marker for early detection of NBNC-HCC in patients with diabetes mellitus. However, further studies are needed to confirm these findings. (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - June 3, 2020 Category: Gastroenterology Tags: Original Articles: Hepatology Source Type: research

Vitamin D-related immunomodulation in patients with liver cirrhosis
Conclusion The results show that vitamin D status and VDBP levels are associated with liver cirrhosis severity and patients’ mortality, possibly through a proinflammatory immune response. (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - June 3, 2020 Category: Gastroenterology Tags: Original Articles: Hepatology Source Type: research

Helicobacter pylori infection may increase the severity of nonalcoholic fatty liver disease via promoting liver function damage, glycometabolism, lipid metabolism, inflammatory reaction and metabolic syndrome
Background and aim Recent clinical trials have confirmed that Helicobacter pylori infection is positively associated with nonalcoholic fatty liver disease (NAFLD), although some research has shown a negative association. Therefore, to confirm whether H. pylori eradication treatment is feasible for NAFLD patients in our hospital, we aimed to establish the association between H. pylori infection and NAFLD. Methods We enrolled 91 patients with NAFLD diagnosed by abdominal B-mode ultrasonography between January and December 2018. H. pylori infection was confirmed by C13 urea breath test, and liver function, glycometabolis...
Source: European Journal of Gastroenterology and Hepatology - June 3, 2020 Category: Gastroenterology Tags: Original Articles: Hepatology Source Type: research

Retrieval and re-evaluation of previously diagnosed chronic hepatitis C infections lost to medical follow-up in the Netherlands
Conclusion During every step of the retrieval chain, many patients were lost. Nevertheless, with substantial effort, we were able to identify, retrieve, and positively re-evaluate a limited number of individuals with a possible chronic HCV infection who were lost to medical follow-up (19 patients). With this case-finding approach, we were able to prevent potential severe complications in these patients and contribute to a small step in the eradication of HCV in the Netherlands. (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - June 3, 2020 Category: Gastroenterology Tags: Original Articles: Hepatology Source Type: research

Changes in the distribution of etiologies of cirrhosis among patients referred for liver transplantation over 11 years in Iran
Background and aim: Cirrhosis is a major public health problem worldwide. The prevalence of cirrhosis is various in different geographical regions. The aim of the present study was to determine the distribution of the etiologies of cirrhosis and their proportional changes through recent 11 years in Iran. Methods: In this retrospective, observational study, the data of cirrhotic patients who have been listed for liver transplantation in the Namazi Transplant Center (Shiraz, Iran) between January 2006 and December 2016 were analyzed. Demographic and clinical data of the patients including model for end-stage liver disea...
Source: European Journal of Gastroenterology and Hepatology - June 3, 2020 Category: Gastroenterology Tags: Original Articles: Hepatology Source Type: research

Ultrasonographic assessment of right heart intracardiac mass in patients with hepatitis B virus infection
Objective: The characteristics of right heart intracardiac mass in hepatitis B virus infection patients are not well known. Our aim is to describe their ultrasonographic features and nature of such masses. Methods: We retrospectively reviewed imaging reports of hepatitis B virus infection patients from January 2014 to December 2018. Patients with a confirmed finding of right heart intracardiac mass were included, whose pathology reports and contrast-enhanced images were analyzed. Various masses were compared to a general control group from a published study. Results: Thirty-eight cases were finally included. Differ...
Source: European Journal of Gastroenterology and Hepatology - June 3, 2020 Category: Gastroenterology Tags: Original Articles: Hepatology Source Type: research

The gastrointestinal endoscopy satisfaction questionnaire captures patient satisfaction as a key quality indicator of gastrointestinal endoscopy
Conclusion The Dutch version of the GESQ showed high internal validity and practicality. We recommend the D-GESQ for routine use in endoscopy practice to improve quality of patient care. (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - June 3, 2020 Category: Gastroenterology Tags: Original Articles: Gastroenterology Source Type: research

Esophageal foreign bodies: observational cohort study and factors associated with recurrent impaction
Background and aim Esophageal foreign bodies, including food bolus impaction, represent a common clinical problem. The prevalence of underlying esophageal disease depends on study design and degree of suspicion of a structural or functional esophageal abnormality. Aim of this study was to analyze factors associated with recurrent impaction. Methods The prospectively collected database at a University Hospital and Swallowing Center was reviewed from January 2012 to June 2019 to identify all patients admitted for esophageal foreign bodies. Patients who underwent an emergency endoscopic procedure represented the final st...
Source: European Journal of Gastroenterology and Hepatology - June 3, 2020 Category: Gastroenterology Tags: Original Articles: Gastroenterology Source Type: research

Symptoms and demographic factors associated with early-onset colorectal neoplasia among individuals undergoing diagnostic colonoscopy
Conclusions: In the largest study to date of symptomatic individuals under 50 years of age undergoing colonoscopy in the USA, advanced CRN was most often detected in the distal colon and was associated with anemia, but not with abnormal bowel habits or abdominal pain. We also found that patients with CRN under 50 years of age were more likely to be male, smokers, and obese. These findings should prompt further investigation of these risk factors alone and in combination. (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - June 3, 2020 Category: Gastroenterology Tags: Original Articles: Gastroenterology Source Type: research

Upregulation of microRNA-219-5p relieves ulcerative colitis through balancing the differentiation of Treg/Th17 cells
This study aimed to investigate the specific regulatory roles of microRNA-219-5p (miR-219-5p) on ulcerative colitis (UC), and reveal the potential mechanisms relating with the differentiation of Treg/Th17 cells. Methods: The mouse model of chronic UC was established by oral administration of 3% dextran sodium sulfate for three cycles. After intravenous injected with lentivirus (LV)-miR-219-5p for 24 h, the disease activity index (DAI), colon length, as well as the serum levels of Interleukin (IL)-6, -17A, -21, and -23 were measured. In addition, the histopathological changes in colon tissues were observed by Hematoxylin...
Source: European Journal of Gastroenterology and Hepatology - June 3, 2020 Category: Gastroenterology Tags: Original Articles: Gastroenterology Source Type: research

Feasibility and learning curve of unsupervised colorectal endoscopic submucosal hydrodissection at a Western Center
Conclusion CR-ESD by hydrodissection has good safety and efficacy profile and offers well tolerated and effective treatment for complex polyps. As such, this technique may be useful in the West, in centers, where previous gastric ESD is not frequent or Japanese mentoring is not possible. (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - June 3, 2020 Category: Gastroenterology Tags: Original Articles: Gastroenterology Source Type: research

Is coffee ground vomiting important? Findings from a large bleeding unit database and outcomes at 30 days
Objectives: ‘Coffee ground’ vomiting (CGV) has classically been considered a sign of upper gastrointestinal bleeding. There is a paucity of data concerning endoscopic findings and outcomes in patients presenting with CGV. The aim of this study was to analyze endoscopic yield and 30-day outcomes in CGV patients. Methods: Analysis was performed over the period 1992–2005 and four groups were identified: CGV alone, hematemesis alone, melena alone, and hematemesis and melena. Endoscopic yield, requirement for blood transfusion, rebleeding, and mortality rate at 30 days were calculated and compared ...
Source: European Journal of Gastroenterology and Hepatology - June 3, 2020 Category: Gastroenterology Tags: Original Articles: Gastroenterology Source Type: research

Endoscopic resection of early squamous neoplasia of the oesophagus: long-term follow-up in a UK population from a tertiary hospital
Conclusion In UK, endoscopic resection is useful in the management of early squamous neoplasia both for staging and (by piecemeal endoscopic resection in elderly unfit) for medium- to long-term disease clearance. (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - June 3, 2020 Category: Gastroenterology Tags: Original Articles: Gastroenterology Source Type: research

Tumor-associated antigens and their antibodies in the screening, diagnosis, and monitoring of esophageal cancers
Despite the advances in the treatment and management, esophageal cancers continue to carry a dismal prognosis with an overall 5-year survival rate ranging from 15 to 25%. Delayed onset of symptoms and lack of effective screening methods and guidelines for diagnosis of the early disease contribute to the high mortality rate of esophageal cancers. Detection of esophageal cancer at their early stage is really a challenge for physicians including primary care physicians, gastroenterologists and oncologists. Although imaging, endoscopy and biopsy have been proved to be useful diagnostic tools for esophageal cancers, their diagn...
Source: European Journal of Gastroenterology and Hepatology - June 3, 2020 Category: Gastroenterology Tags: Review Articles Source Type: research

Prognostic role of preoperative albumin-bilirubin grade on patients with hepatocellular carcinoma after surgical resection: a systematic review and meta-analysis
Recent studies have reported albumin-bilirubin (ALBI) grade affected the prognosis of patients with hepatocellular carcinoma (HCC). To more precisely evaluate the relationship among the ALBI grade and the prognosis of patients with HCC after liver resection. We systematically retrieved articles from PubMed, Web of Science, Cochrane Library, and CNKI. The prognostic value of ALBI grade on overall survival (OS) and recurrence-free survival (RFS) of patients with HCC after liver resection was evaluated by pooled hazard ratio (HR) with 95% confidence interval (CI).Through multiple databases search, we enrolled 20 high-quality ...
Source: European Journal of Gastroenterology and Hepatology - June 3, 2020 Category: Gastroenterology Tags: Review Articles Source Type: research

Paper alert
No abstract available (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - May 1, 2020 Category: Gastroenterology Tags: Paper Alerts Source Type: research

Increased neuroendocrine tumours, but small colorectal cancer incidence in patients with inflammatory bowel disease treated by mesalazine
No abstract available (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - May 1, 2020 Category: Gastroenterology Tags: Letters to the Editor Source Type: research

Transjugular intrahepatic portosystemic shunt in cirrhotic patients with portal vein thrombosis
No abstract available (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - May 1, 2020 Category: Gastroenterology Tags: Letters to the Editor Source Type: research

MRI-determined liver fat correlates with risk of metabolic syndrome in patients with nonalcoholic fatty liver disease
Background and aim: Little is known about that the relationship between hepatic fat content (HFC) and metabolic syndrome (MetS). We aimed to determine whether HFC correlated with MetS in patients with nonalcoholic fatty liver disease (NAFLD). Methods: HFC was measured by MRI-determined proton density fat fraction (MRI-PDFF) for 131 suspected NAFLD subjects. Patients with NAFLD defined as MRI-PDFF ≥5% were stratified into two groups based on whether they were above or below the median MRI-PDFF value; the MRI-PDFF value for the control group was (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - May 1, 2020 Category: Gastroenterology Tags: Original Articles: Hepatology Source Type: research

Correlation of serum zinc levels with pathological and laboratory findings in patients with nonalcoholic fatty liver disease
Objective Chronic liver diseases are associated with zinc (Zn) deficiency. However, no previous studies have examined the relationship between serum Zn levels and hepatic pathological findings in patients with nonalcoholic fatty liver disease (NAFLD). The aim of this study was to investigate the serum Zn levels in NAFLD patients based on pathological/laboratory findings. Methods We evaluated a total of 191 NAFLD patients who underwent liver biopsy with the goal of identifying laboratory markers and pathological findings associated with serum Zn levels. Results Zn levels significantly decreased along with progressio...
Source: European Journal of Gastroenterology and Hepatology - May 1, 2020 Category: Gastroenterology Tags: Original Articles: Hepatology Source Type: research

Establishment and validation of a risk prediction model in patients with hepatocellular carcinoma treated with transarterial radioembolization
Background/aims Few studies have reported the treatment outcomes of transarterial radioembolization (TARE) using yttrium-90 (90Y) for hepatocellular carcinoma (HCC). We established and validated a new risk prediction model for patients with HCC treated with TARE. Methods Between 2010 and 2017, 113 and 35 patients with intrahepatic HCC treated with TARE were selected for the training and validation cohorts, respectively. The modified response evaluation criteria in solid tumors (mRECIST) were used for response evaluation. Results In the training cohort, the median age was 64.1 years (92 males and 21 females) ...
Source: European Journal of Gastroenterology and Hepatology - May 1, 2020 Category: Gastroenterology Tags: Original Articles: Hepatology Source Type: research

Sarcopenia is associated with longer hospital stay and multiorgan dysfunction in alcoholic hepatitis
Conclusion: Alcoholic hepatitis patients with sarcopenia have significantly worse outcomes when compared with the patients without sarcopenia, including a severe form of alcoholic hepatitis, longer hospital stays, higher risk of developing pneumonia, sepsis and hepatic encephalopathy. (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - May 1, 2020 Category: Gastroenterology Tags: Original Articles: Hepatology Source Type: research

Profiling the patient with autoimmune hepatitis on calcineurin inhibitors: a real-world-experience
Conclusion CNI treatment in AIH as second- or third-line therapy is effective in ~50% of patients. The trajectory before switch varies considerably between patients. (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - May 1, 2020 Category: Gastroenterology Tags: Original Articles: Hepatology Source Type: research

Recurrence of spontaneous bacterial peritonitis in cirrhosis: novel predictors
Conclusion Increased ascitic calprotectin and IP-10, hypoalbuminemia, nonuse of prophylactic β-blockers and use of PPI were independently associated with increased SBP recurrence rate. Sepsis-related organ failure was the most common etiology of mortality. (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - May 1, 2020 Category: Gastroenterology Tags: Original Articles: Hepatology Source Type: research

The risk of residual or recurring adenoma after piecemeal endoscopic mucosal resection of large non-pedunculated colorectal polyps is predictable
Conclusion SMSA and SERT scores are effective tools to identify lesions with a low risk of residual/recurrent adenoma. (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - May 1, 2020 Category: Gastroenterology Tags: Original Articles: Gastroenterology Source Type: research

Clinical efficacy and safety of ketotifen in treating irritable bowel syndrome with diarrhea
Objective: The aim of the study was to investigate the clinical efficacy and safety of ketotifen for the treatment of irritable bowel syndrome with diarrhea (IBS-D). Methods: A total of 108 enrolled IBS-D patients were randomly divided into a ketotifen group (n = 55) and a control (placebo) group (n = 53). The patients in the ketotifen group received ketotifen tablets (1 mg, oral) two times daily; patients in the control group received oral placebo for 8 weeks. Before and after 8 weeks of treatment, gastrointestinal symptoms, anorectal sensory function and the number an...
Source: European Journal of Gastroenterology and Hepatology - May 1, 2020 Category: Gastroenterology Tags: Original Articles: Gastroenterology Source Type: research

Narrow band imaging characteristics of gastric polypoid lesions: a single-center prospective pilot study
Introduction: Gastric polypoid lesions (GPL) are endoscopic findings whose histological nature is difficult to determine with white-light endoscopy. Hyperplastic polyps (HP), type-1 gastric carcinoids (T1-GC) and adenomas are the most frequent GPL needing different management. Narrow-band imaging (NBI) has high accuracy for gastric malignant lesions but few studies assessed whether GPL display specific NBI characteristics. We aimed to investigate the endoscopic NBI appearances of GPL. Materials and methods: During gastroscopies, images of GPL were recorded, and lesions were removed for histological evaluation. Two end...
Source: European Journal of Gastroenterology and Hepatology - May 1, 2020 Category: Gastroenterology Tags: Original Articles: Gastroenterology Source Type: research

The microbiology of necrotizing pancreatitis and its impact on in-hospital and 1-year all-cause mortality
Background/objectives: The data regarding the microbial spectrum in necrotizing pancreatitis and its impact on mortality is limited. Therefore, in this study, we aimed to investigate the agents identified in cultures and their impact on in-hospital and 1-year all-cause mortality. Methods: Patients with necrotizing pancreatitis were retrospectively included in the study. Based on culture results, patients were classified as either negative culture or positive culture necrotizing acute pancreatitis. The main outcomes of the study were the identification of agents isolated in patients with pancreatic necrosis and to asse...
Source: European Journal of Gastroenterology and Hepatology - May 1, 2020 Category: Gastroenterology Tags: Original Articles: Gastroenterology Source Type: research

Effectiveness of Helicobacter pylori eradication in preventing metachronous gastric cancer and preneoplastic lesions. A systematic review and meta-analysis
Background: Helicobacter pylori is a significant risk factor for gastric cancer. Recent trials show eradication decreases the incidence of gastric cancer in patients with early-stage gastric cancer. However, data on gastric cancer prevention are inconsistent for patients with precancerous lesions such as atrophic gastritis and intestinal metaplasia. Aim: The aim of the study is to assess the efficacy of H. pylori eradication in gastric cancer prevention in patients with varying risk factors for gastric cancer at baseline. Methods: A systematic review and meta-analysis were performed according to Preferred Reporting...
Source: European Journal of Gastroenterology and Hepatology - May 1, 2020 Category: Gastroenterology Tags: Review Articles Source Type: research

Systematic review and meta-analysis: monopolar hemostatic forceps with soft coagulation in the treatment of peptic ulcer bleeding
Monopolar hemostatic forceps with soft coagulation (MHFSC) have been compared with hemoclips, heater probe, and argon plasma coagulation (APC) for the treatment of peptic ulcer bleeding. In this systematic review and meta-analysis, we compared MHFSC with other modalities in the treatment of peptic ulcer bleeding. We reviewed MEDLINE, Embase, Scopus, Cochrane, Web of Science, and Scopus from inception to 7 January 2019 to identify studies comparing MHFSC with other modalities for peptic ulcer bleeding. The primary outcome of interest was achievement of initial hemostasis. Secondary outcomes were rebleeding, adverse events, ...
Source: European Journal of Gastroenterology and Hepatology - May 1, 2020 Category: Gastroenterology Tags: Review Articles Source Type: research

Small molecule drugs in the treatment of inflammatory bowel diseases: which one, when and why? – a systematic review
In the ‘treat-to-target’ era of inflammatory bowel disease (IBD) management, small molecule drugs (SMDs) represent a promising alternative to biomolecular drugs. Moreover, increasing failure rates of anti-tumor necrosis factor α agents have contributed to the development of new molecules with different mechanisms of action and bioavailability. This review focuses on the positioning of new, orally targeted therapies in the treatment algorithm of both Crohn’s disease (CD) and ulcerative colitis (UC), with special consideration to their efficacy and safety. We performed a comprehensive search of PubMed...
Source: European Journal of Gastroenterology and Hepatology - May 1, 2020 Category: Gastroenterology Tags: Review Articles Source Type: research

Recurrent ‘gloves and socks’ distribution with bullous eruptions after adalimumab and infliximab treatment in a patient with Crohn’s disease
No abstract available (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - April 8, 2020 Category: Gastroenterology Tags: Letters to the Editor Source Type: research

An unusual case of a gastric submucosal tumor: an intraparietal schwannoma
No abstract available (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - April 8, 2020 Category: Gastroenterology Tags: Letters to the Editor Source Type: research

Clinical utility of mean platelet volume and related scores for assessing the severity of hepatic fibrosis in chronic hepatitis C patients
No abstract available (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - April 8, 2020 Category: Gastroenterology Tags: Letters to the Editor Source Type: research

Fecal calprotectin concentrations in patients with hereditary transthyretin amyloidosis and gastrointestinal symptoms
No abstract available (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - April 8, 2020 Category: Gastroenterology Tags: Letters to the Editor Source Type: research

Short-term, low dose vitamin D supplementation in young patients with celiac disease: a pilot study
No abstract available (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - April 8, 2020 Category: Gastroenterology Tags: Letters to the Editor Source Type: research

The combination of balloon-assisted antegrade transvenous obliteration and transjugular intrahepatic portosystemic shunt for the management of cardiofundal varices hemorrhage
Conclusion: For the treatment of GVs, the new technique BAATO is feasible, safe and effective, and it may be a more convenient and economical method than conventional BRTO. In addition, the combination of BAATO and TIPS may play a positive role in achieving hemostasis and improving the complications of portal hypertension such as ascites and PVT. (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - April 8, 2020 Category: Gastroenterology Tags: Original Articles: Hepatology Source Type: research

Hepatitis A hospitalizations among kidney transplant recipients in the United States: nationwide inpatient sample 2005–2014
Conclusion Overall, inpatient prevalence of HAV in KTx recipients in the United States (years 2005–2014) was 23.42 cases per 100 000 admissions. Hospitalization for HAV after KTx is associated with increased ICU stay, coexisting hepatitis B and C infection, and liver failure. (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - April 8, 2020 Category: Gastroenterology Tags: Original Articles: Hepatology Source Type: research

The diagnostic utility of fibrosis-4 or nonalcoholic fatty liver disease fibrosis score combined with liver stiffness measurement by fibroscan in assessment of advanced liver fibrosis: a biopsy-proven nonalcoholic fatty liver disease study
Conclusion: A paired combination of the fibrosis-4 score and liver stiffness measurement ( 10.9 kPa for inclusion of advanced fibrosis) is able to diagnose the patients with advanced fibrosis with the highest diagnostic accuracy. (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - April 8, 2020 Category: Gastroenterology Tags: Original Articles: Hepatology Source Type: research

Persistence and adherence to nucleos(t)ide analogues in chronic hepatitis B: a multicenter cohort study
Conclusion In this real-world cohort of chronic hepatitis B patients, high adherence to nucleos(t)ides analogues was coupled with suboptimal persistence with prescribing the medication. Our data indicate that persistence and adherence are distinct measures that should be approached separately in educational programs targeting to improve medication-taking behavior in chronic hepatitis B. (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - April 8, 2020 Category: Gastroenterology Tags: Original Articles: Hepatology Source Type: research

Sarcopenia as prognostic factor for survival after orthotopic liver transplantation
Background and aim Body composition has emerged as a prognostic factor for end-stage liver disease. We therefore investigated muscle mass, body fat and other clinical–pathological variables as predictors of posttransplant survival. Methods A total of 368 patients, who underwent orthotopic liver transplantation (OLT) at our institution, were assessed prior to OLT and followed for a median of 9.0 years (range 2.0–10.0 years) after OLT. Psoas, erector spinae and the combined paraspinal muscle area, as well as the corresponding indices normalized by body-height squared, were quantified by a lumbar (L3) ...
Source: European Journal of Gastroenterology and Hepatology - April 8, 2020 Category: Gastroenterology Tags: Original Articles: Hepatology Source Type: research

Patterns of splenic arterial enhancement on computed tomography scan are related to portal venous hypertension
Objectives: We have previously shown that patterns of splenic arterial enhancement on computed tomography scan change following liver transplantation. We suggested that this is related to changes in portal venous pressure. The aim of this study was to see if similar patterns occur in patients with and without portal hypertension and in patients before and after portal systemic shunts (transjugular portosystemic shunts). Methods: We evaluated contrast enhanced computed tomography scans in patients being evaluated for liver disease and compared those from patients with and without portal hypertension. In addition we eva...
Source: European Journal of Gastroenterology and Hepatology - April 8, 2020 Category: Gastroenterology Tags: Original Articles: Hepatology Source Type: research

Influence of esophageal variceal bleeding on iron status in chronic hepatitis C patients
Conclusion Esophageal bleeding has an almost no influence on iron status in CHC patients. Serum hepcidin content is influenced by CHC disease rather than by anemia associated with or without esophageal bleeding and it could be used as a marker of early hepatic insufficiency. Assessing CHr content could add a potential utility in the detection of iron deficiency in CHC patients. (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - April 8, 2020 Category: Gastroenterology Tags: Original Articles: Hepatology Source Type: research