Paper alert
No abstract available (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - January 7, 2021 Category: Gastroenterology Tags: Paper Alert Source Type: research

Duodenal bulb infection may be a risk factor for Helicobacter pylori eradication insuccess
No abstract available (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - January 7, 2021 Category: Gastroenterology Tags: Letters to the Editor Source Type: research

Rate of lymph node metastasis in patients with T1 gastric carcinoid tumors
No abstract available (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - January 7, 2021 Category: Gastroenterology Tags: Letters to the Editor Source Type: research

Reply to the letter to the Editor: ‘The role of coexisting cardiovascular disease on disease severity in patients with inflammatory bowel disease’
No abstract available (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - January 7, 2021 Category: Gastroenterology Tags: Letters to the Editor Source Type: research

Response to Letter: ‘Serological exclusion of coeliac disease: an audit of anti-tissue transglutaminase and immunoglobulin A testing’
No abstract available (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - January 7, 2021 Category: Gastroenterology Tags: Letters to the Editor Source Type: research

Predictive value of protein induced by absence of vitamin K absence or antagonist II, alpha-fetoprotein and gamma-glutamyltransferase/aspartate aminotransferase ratio for the diagnosis of hepatocellular carcinoma in transplantation candidates
Objectives Alpha-fetoprotein (AFP) and protein induced by vitamin K absence or antagonist-II (PIVKA-II) are used as tumour markers for the diagnosis of hepatocellular carcinoma (HCC). We investigate whether combined liver function marker such as gamma-glutamyl transferase (GGT) and aspartate aminotransferase (AST) with alpha-fetoprotein (AFP) and PIVKA-II increase their diagnostic predictive value in diagnosis of HCC. Methods The serum levels of PIVKA-II, AFP and GGT/AST ratio were analysed in 112 transplant candidates. Of these patients, 66 (59%) had HCC and 46 (41%) patients did not. Results Histologica...
Source: European Journal of Gastroenterology and Hepatology - January 7, 2021 Category: Gastroenterology Tags: Original Articles: Hepatology Source Type: research

L-carnitine reduces hospital admissions in patients with hepatic encephalopathy
Aim The aim of this study was to determine whether oral L-carnitine administration reduces the blood ammonia concentration and number of hospital admissions for hepatic encephalopathy in patients with advanced cirrhosis. Methods Of 68 patients with hepatic encephalopathy treated with oral L-carnitine supplementation from April 2013 to March 2016, we enrolled 19 patients who had received full standard treatment. We analyzed blood ammonia concentration, number of hospital admissions, and prognosis to determine how effective L-carnitine was in achieving mid-term to long-term suppression of recurrent hepatic encepha...
Source: European Journal of Gastroenterology and Hepatology - January 7, 2021 Category: Gastroenterology Tags: Original Articles: Hepatology Source Type: research

Impact of interferon-free therapies in HIV/HCV co-infected patients on real clinical practice: results from a multicenter region-wide cohort study (2014–2018)
Conclusion Despite numerous difficulties in treatment access and in adaptation to the changing guidelines, we detected no differences among the DAAs used, nor did we detect a lower efficacy when the chosen treatment was not optimal. (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - January 7, 2021 Category: Gastroenterology Tags: Original Articles: Hepatology Source Type: research

The effect of malnutrition on the infectious outcomes of hospitalized patients with cirrhosis: analysis of the 2011–2017 hospital data
This study used the 2011–2017 National Inpatient Sample to identify patients with cirrhosis. These patients were stratified using malnutrition (protein-calorie malnutrition, cachexia, and sarcopenia) and matched using age, gender, and race with 1:1 nearest neighbor matching method. The endpoints included mortality and infectious outcomes. Results After matching, there were 96 842 malnutrition-present cohort and equal number of controls. In univariate analysis, the malnutrition cohort had higher hospital mortality [10.40 vs. 5.04% P (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - January 7, 2021 Category: Gastroenterology Tags: Original Articles: Hepatology Source Type: research

Platelet–lymphocyte ratio predicts survival in patients with hepatocellular carcinoma who receive lenvatinib: an inverse probability weighting analysis
Conclusions PLR predicted overall survival in patients with unresectable HCC who received lenvatinib. (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - January 7, 2021 Category: Gastroenterology Tags: Original Articles: Hepatology Source Type: research

Comparison of the impact of tenofovir alafenamide and entecavir on declines of hepatitis B surface antigen levels
In this study, we compared entecavir and tenofovir alafenamide in terms of their ability to reduce hepatitis B surface antigen (HBsAg) in the same group of patients with HBV infection. Methods: During March and June 2018, 129 patients who received entecavir were switched to tenofovir alafenamide. Every 3– 6 months for 1 year before and after switching to tenofovir alafenamide, all patients underwent measurements of HBsAg, hepatitis core-related antigen (HBcrAg), calcium (Ca), inorganic phosphorus, and estimated glomerular filtration rate (eGFR). Results: The percent decline rate during the...
Source: European Journal of Gastroenterology and Hepatology - January 7, 2021 Category: Gastroenterology Tags: Original Articles: Hepatology Source Type: research

Association between effective hepatic blood flow and the severity and prognosis of hepatitis B virus-related acute on chronic liver failure
Background: Hepatic inflammation resulted in hepatocyte necrosis and microcirculatory dysfunction in acute on chronic liver failure (ACLF) with cirrhosis or not. The influence of effective hepatic blood flow (EHBF) on the severity of liver failure has not been fully elucidated. Aim: The aim of this study was to assess the correlation between the EHBF and the severity and the prediction of 90-day mortality rate of hepatitis B virus-related ACLF (HBV-ACLF). Methods: In this retrospective study, patients hospitalized for HBV-ACLF or decompensated cirrhosis and who underwent an indocyanine green (ICG) clearan...
Source: European Journal of Gastroenterology and Hepatology - January 7, 2021 Category: Gastroenterology Tags: Original Articles: Hepatology Source Type: research

Accuracy of liver and spleen stiffness on magnetic resonance elastography for detecting portal hypertension: a systematic review and meta-analysis
Discussion Liver and spleen stiffness on MRE can serve as a supplemental noninvasive assessment tools for detecting clinically significant portal hypertension. Spleen stiffness may be more specific and accurate than liver stiffness for detecting portal hypertension. (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - January 7, 2021 Category: Gastroenterology Tags: Original Articles: Hepatology Source Type: research

Serum ammonia as a non-invasive marker for early prediction of esophageal varices
Introduction: There is a growing need for identification of non-endoscopic, non-invasive methods that can accurately predict esophageal varices (EV). Previous studies found an inconclusive correlation between blood ammonia level and the presence and size of EV. Aim: We aimed at assessing the value of serum ammonia as a non-invasive method for early prediction of EV. Patient and methods: The study included 204 patients with HCV-related cirrhosis. The selected patients were categorized into two groups: patients with EV and those without, also patients with no or small EV and with large EV group. All patient...
Source: European Journal of Gastroenterology and Hepatology - January 7, 2021 Category: Gastroenterology Tags: Original Articles: Hepatology Source Type: research

Liver stiffness across different chronic liver disease under therapy with statin in a real life cohort
Introduction Statins have been associated with improved clinical outcomes in patients with viral hepatitis and after variceal bleeding. Still, the clinical benefit of statins is not well defined for different liver diseases. Moreover, associations between statin use and liver stiffness as well as event free survival have not been established. Methods Liver stiffness was evaluated in 6490 patients with liver disease (January 2012 till December 2016). Two hundred thirty-four of those received statin therapy, 468 controls without statins were selected by a 1:2 case by case matching using age, sex, underlying liver ...
Source: European Journal of Gastroenterology and Hepatology - January 7, 2021 Category: Gastroenterology Tags: Original Articles: Hepatology Source Type: research

Impact of HCV cure with drug-acting antivirals in the use of concomitant medication and lipid profile: follow-up data 2 years after the sustained virological response
Background and aim: Patients with chronic hepatitis C (CHC) frequently associated comorbidities and concomitant medication. Sustained virological response (SVR12) has been related to an increase in cholesterol serum levels and in peripheral vascular resistance. Our aim was to evaluate the impact of SVR12 on the use of concomitant medication and serum lipid profile. Methods: Prospective study including patients treated with direct-acting antivirals who had achieved the SVR12. Clinical data and concomitant drugs were analysed at baseline and at least 1 year after SVR12. Differences from baseline to follow-up in th...
Source: European Journal of Gastroenterology and Hepatology - January 7, 2021 Category: Gastroenterology Tags: Original Articles: Hepatology Source Type: research

Comparison of tenofovir and entecavir in the development of acute kidney injury in cirrhotic chronic hepatitis B patients with refractory ascites
Conclusions: TDF treatment is a risk factor for AKI and HRS development in cirrhotic patients with refractory ascites in comparison with entecavir treatment, especially in patients with comorbidity. (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - January 7, 2021 Category: Gastroenterology Tags: Original Articles: Hepatology Source Type: research

Safety and efficacy of switching from infliximab biosimilar CT-P13 to infliximab biosimilar SB2 in patients with inflammatory bowel disease
Conclusion Switching from CT-P13 to SB2 seems to be safe and effective either in patients with a single than in those with multiple switches. (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - January 7, 2021 Category: Gastroenterology Tags: Original Articles: Gastroenterology Source Type: research

Comparative study of allicin-containing quadruple therapy vs. bismuth-containing quadruple therapy for the treatment of Helicobacter pylori infection: a prospective randomized study
Conclusion Allicin-containing quadruple therapy might be regarded as a promising alternative to bismuth-containing quadruple therapy in H. pylori eradication. (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - January 7, 2021 Category: Gastroenterology Tags: Original Articles: Gastroenterology Source Type: research

Mixed histology poses a greater risk for noncurative endoscopic resection in early gastric cancers regardless of the predominant histologic types
Objectives Clinicopathologic characteristics and treatment outcomes of mixed-histological-type (MT) early gastric cancers (EGCs) treated with endoscopic submucosal dissection (ESD) have not been sufficiently elucidated. We aimed to clarify them in comparison with pure-histological-type EGCs. Methods We used 3022 consecutive EGCs in 2281 patients treated with ESD from our prospectively maintained database. Cases were stratified into four groups according to the final diagnosis of the resected specimen are as follows: 2780 pure differentiated-type (DT), 127 DT-predominant MT (D-MT), 87 pure undifferentiated-type (...
Source: European Journal of Gastroenterology and Hepatology - January 7, 2021 Category: Gastroenterology Tags: Original Articles: Gastroenterology Source Type: research

IL-10-1082G>A polymorphism, use of opioids and age affect the course of acute pancreatitis
Conclusion Our study suggests the IL-10 -1082A allele as a protective factor in acute pancreatitis. Opioid analgesics treatment in acute pancreatitis is associated with severity, complications and mortality, while advanced age increases the risk of systemic complications. (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - January 7, 2021 Category: Gastroenterology Tags: Original Articles: Gastroenterology Source Type: research

Carbohydrate-induced gastrointestinal symptoms: development and validation of a test-specific symptom questionnaire for an adult population, the adult Carbohydrate Perception Questionnaire
Objectives Carbohydrate intolerances may affect a majority of the worlds-population but there is no validated, test-specific assessment of carbohydrate-induced symptoms during breath tests. We aimed to develop and validate a questionnaire for evaluation and quantification of carbohydrate intolerance. Methods A visual analog scale-questionnaire with five complaints (pain, nausea, bloating, flatulence, and diarrhea) was designed. The time frame of symptoms was ‘current’ (for baseline symptoms) and ‘since filling out the last questionnaire’. Validity was determined in focus-group style inter...
Source: European Journal of Gastroenterology and Hepatology - January 7, 2021 Category: Gastroenterology Tags: Original Articles: Gastroenterology Source Type: research

A randomized, double-blind, placebo-controlled pilot study to evaluate the efficacy and tolerability of a novel oral bioadhesive formulation for the treatment of nonerosive reflux disease-related symptoms
Objective The use of antisecretory drugs can provide symptomatic relief in 70–80% of patients suffering from gastro-oesophageal reflux disease (GORD), although this benefit is reduced by 20–30% in the case of nonerosive reflux disease (NERD). The current study evaluates the efficacy and safety of a patented oral formulation (liquid sachets containing hyaluronic acid, a mixture of amino acids including proline, hydroxyl-proline and glutamine, and rice extract dispersed in a bioadhesive polymer matrix) for relieving the symptoms of NERD. Methods A single-centre, randomized, double-blind, parallel group...
Source: European Journal of Gastroenterology and Hepatology - January 7, 2021 Category: Gastroenterology Tags: Original Articles: Gastroenterology Source Type: research

A novel value-based scoring system for endoscopic ultrasound-guided drainage of pancreatic fluid collections: a single-centre comparative study of plastic and lumen-apposing metal stents (NOVA study)
Conclusion In this single-centre study, EUS-guided PFC drainage using LAMS was found to be a higher value procedure compared to the use of DPPS. (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - January 7, 2021 Category: Gastroenterology Tags: Original Articles: Gastroenterology Source Type: research

Concomitant decrease of double-positive lymphocyte population CD4CD8αα and Faecalibacterium prausnitzii in patients with colorectal cancer
Conclusion In our work, we showed that a reduced abundance of F. prausnitzii in CRC patients was associated to a significant decrease in the circulating DP8α Treg population, suggesting a potential involvement of reduced activity of DP8α T cells in colonic carcinogenesis. These findings open new diagnostic and therapeutic strategies for CRC. (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - January 7, 2021 Category: Gastroenterology Tags: Original Articles: Gastroenterology Source Type: research

microRNA in inflammatory bowel disease at a glance
This article reviews important researches that have recently been done on miRNAs roles in CD and UC disease. First, miRNA is introduced and its biogenesis and function are discussed. Afterward, roles of miRNAs in inflammatory processes involved in IBD are showed. Finally, this review proposes some circulating and tissue-specific miRNAs, which are useful for CD and UC fast diagnosis and grade prediction. As a conclusion, miRNAs are efficient diagnostic molecules especially in IBD subtypes discrimination and can be used by microarray and real time PCR methods for disease detection and classification. (Source: European Journa...
Source: European Journal of Gastroenterology and Hepatology - January 7, 2021 Category: Gastroenterology Tags: Reviews Source Type: research

The interplay between gastrointestinal and cardiovascular diseases: a narrative review focusing on the clinical perspective
Both cardiovascular and gastrointestinal disorders represent considerable health burden on community clinics and hospitals with overwhelming economic cost. An overlap in the occurrence of these disorders is encountered in daily practice. Both affect each other in bidirectional manner through several mechanisms including altered hemodynamics, systemic inflammation, bacterial overgrowth and interactions and adverse effects of medications. In addition, to the known overlap in the symptoms occurrence of upper gastrointestinal tract diseases and cardiovascular diseases (CVDs). Awareness of this interplay and its clinical manife...
Source: European Journal of Gastroenterology and Hepatology - January 7, 2021 Category: Gastroenterology Tags: Reviews Source Type: research

Association of portal venous system thrombosis with endoscopic variceal treatment: a systematic review and meta-analysis
The association of endoscopic variceal treatment (EVT) with the development of portal venous system thrombosis (PVST) in liver cirrhosis remains uncertain. A systematic review and meta-analysis aimed to investigate the incidence of PVST after EVT and to explore the association of EVT with the development of PVST in liver cirrhosis. All relevant studies were searched via the PubMed, EMBASE, and Cochrane Library databases. The incidence of PVST in patients treated with and without EVT was pooled. Risk ratios with 95% confidence intervals (CIs) were calculated. Heterogeneity among studies was calculated. Meta-regression, sens...
Source: European Journal of Gastroenterology and Hepatology - January 7, 2021 Category: Gastroenterology Tags: Reviews Source Type: research

Paper alert
No abstract available (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - December 2, 2020 Category: Gastroenterology Tags: Paper Alert Source Type: research

Epidemiology and seasonal pattern in hospitalizations for microscopic colitis
No abstract available (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - December 2, 2020 Category: Gastroenterology Tags: Letters to the Editor Source Type: research

A rare cause of dysphagia: gastro-esophageal junction actinomycosis diagnosed with endoscopic ultrasound
No abstract available (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - December 2, 2020 Category: Gastroenterology Tags: Letters to the Editor Source Type: research

Higher salivary expression of S100A12 in patients with ulcerative colitis and chronic periodontitis
No abstract available (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - December 2, 2020 Category: Gastroenterology Tags: Letters to the Editor Source Type: research

Association between occupation type and progression of Barrett’s oesophagus to oesophageal adenocarcinoma
No abstract available (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - December 2, 2020 Category: Gastroenterology Tags: Letters to the Editor Source Type: research

Chronic liver disease is not associated with severity or mortality in Coronavirus disease 2019 (COVID-19): a pooled analysis
No abstract available (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - December 2, 2020 Category: Gastroenterology Tags: Letters to the Editor Source Type: research

Monitoring by viral load and quantitative hepatitis B surface antigen in patients with hepatitis B virus infection receiving immunosuppressive therapy
Conclusion: Monitoring hepatitis B virus DNA and quantitative hepatitis B surface antigen every 2 months is safe. However, antiviral prophylaxis can prevent hepatitis B virus reactivation. For patients under steroid therapy in high-risk doses, quantitative hepatitis B surface antigen increase of>0.5 log IU/mL may signify hepatitis B virus reactivation. (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - December 2, 2020 Category: Gastroenterology Tags: Original Articles: Hepatology Source Type: research

Standardized approach of albumin, midodrine and octreotide on hepatorenal syndrome treatment response rate
Conclusion: A trend towards improved treatment response rate was observed after standardizing the HRS treatment regimen. Standardized therapy led to significantly lower rates of renal replacement therapy and liver transplantation, suggesting patients in poststandardization were effectively managed medically without requiring further intervention. (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - December 2, 2020 Category: Gastroenterology Tags: Original Articles: Hepatology Source Type: research

Hereditary hemochromatosis and risk of joint replacement surgery: a systematic review and meta-analysis
Conclusions: A significantly increased risk of needed joint replacement surgery among patients with hereditary hemochromatosis compared to patients without hereditary hemochromatosis was demonstrated in this study. Further studies are required to determine whether this association is causal. (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - December 2, 2020 Category: Gastroenterology Tags: Original Articles: Hepatology Source Type: research

Performance and cutoffs for liver fibrosis staging of a two-dimensional shear wave elastography technique
Objectives: To assess performance and cutoffs of the 2-dimensional shear wave elastography technique available on the Aplio i800 ultrasound system (Canon Medical Systems, Japan), using transient elastography as reference standard, and to assess the correlation of shear-wave-speed dispersion with liver fibrosis or steatosis. Methods: This was a single-center cross-sectional study. The correlations between values obtained with transient elastography and 2-dimensional-shear wave elastography, and between shear-wave-speed dispersion and fibrosis or steatosis, were assessed with Pearson’s r. The diagnostic perf...
Source: European Journal of Gastroenterology and Hepatology - December 2, 2020 Category: Gastroenterology Tags: Original Articles: Hepatology Source Type: research

Characteristics and outcome of nosocomial bloodstream infection in patients with acute-on-chronic liver failure
Conclusion Gram-negative bacteria were the most prevalent pathogens and ESBL-producing bacteria were responsible for most of the MDR bacteria in patients with ACLF and nosocomial BSI. Higher MELD score and multiorgan failure were associated with worse outcomes. (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - December 2, 2020 Category: Gastroenterology Tags: Original Articles: Hepatology Source Type: research

Expression of hepatitis B surface antigen in liver tissues can serve as a predictor of prognosis for hepatitis B virus-related hepatocellular carcinoma patients after liver resection
This study aimed to explore the potential utility of using HBsAg protein expression in normal liver tissues as a prognostic factor for HCC patients who underwent liver resection. Study design: The study enrolled 100 HCC patients with seropositivity for HBsAg. The liver tissues were collected, and tissue microarrays were constructed. The expression of HBsAg in liver tissues were measured by immunohistochemistry (IHC). Relevant clinical data and follow-up records were collected for analysis. Results: HBsAg expressions was detected in 29 patients (positive group) and was unable to be detected in the remaining 71...
Source: European Journal of Gastroenterology and Hepatology - December 2, 2020 Category: Gastroenterology Tags: Original Articles: Hepatology Source Type: research

A nomogram for discrimination of non-alcoholic fatty liver disease in patients with chronic hepatitis B
Conclusion: This study developed a simple, noninvasive, effective and convenient nomogram that achieved an optimal detection of NAFLD in CHB patients. Using this nomogram, the risk for an individual patient to have NAFLD could be discriminated, leading to a rational clinical management. (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - December 2, 2020 Category: Gastroenterology Tags: Original Articles: Hepatology Source Type: research

Nonalcoholic fatty liver disease is associated with intrahepatic cholangiocarcinoma and not with extrahepatic form: definitive evidence from meta-analysis and trial sequential analysis
Conclusion The performance of new sensitive analyses and the respective trial sequential analyses, after withdraw of confounding factors, suggested the existence of definitive association only between NAFLD and iCCA development and not with eCCA. (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - December 2, 2020 Category: Gastroenterology Tags: Original Articles: Hepatology Source Type: research

Endoscopic remission can be predicted by golimumab concentrations in patients with ulcerative colitis treated with the changed label
Background In 2018, the European Medicines Agency (EMA) replaced a fixed 50 mg every 4-week maintenance regimen of golimumab for ulcerative colitis (UC) patients weighing (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - December 2, 2020 Category: Gastroenterology Tags: Original Articles: Gastroenterology Source Type: research

Obstructive colon cancers at endoscopy are associated with advanced tumor stage and poor patient outcome. A retrospective study on 398 patients
Background The detection of obstructive colorectal cancer (CRC) masses during endoscopic examination hindering the passage of endoscope and precluding complete examination is not uncommon. The significance and implications of this finding on patients’ prognosis and outcomes were not fully investigated and will be addressed in this study. Methods In this retrospective cohort study, we reviewed endoscopy, surgery, pathology and oncology reports of patients diagnosed with CRC over a 10-year period (2007–2016). We compared surgical stages, histologic grades and overall survival between patients with subc...
Source: European Journal of Gastroenterology and Hepatology - December 2, 2020 Category: Gastroenterology Tags: Original Articles: Gastroenterology Source Type: research

The operation training for magnetically controlled capsule endoscopy
Conclusion After the systematic training course, technical staff can be trained for MCE operation. Further studies should be conducted to observe the learning curve of MCE operation. (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - December 2, 2020 Category: Gastroenterology Tags: Original Articles: Gastroenterology Source Type: research

Diagnostic significance of cytomegalovirus DNA quantitation in gastrointestinal biopsies: comparison with histopathological data and blood cytomegalovirus DNA
This study aims to improve the diagnosis of gastrointestinal (GI) cytomegalovirus (CMV) disease. It presents the results of a novel study in which CMV blood viral load (BVL), tissue viral load (TVL) determined by PCR and hematoxylin-eosin (HE)/immunohistochemistry (IHC) results of GI biopsies are examined comparatively. Methods CMV DNA was investigated by quantitative real-time PCR in blood and GI biopsy specimens of 76 patients suspected of CMV disease. Biopsies were also performed HE/IHC stainings in the pathology laboratory. Results This study included 76 patients whose median age was 34.5 years and 58% (4...
Source: European Journal of Gastroenterology and Hepatology - December 2, 2020 Category: Gastroenterology Tags: Original Articles: Gastroenterology Source Type: research

Dual-layer spectral detector computed tomography versus magnetic resonance cholangiopancreatography for biliary stones
This study seeks to compare the diagnostic ability for biliary stones between these two imaging modalities. Methods This retrospective study included 102 cases with a diagnosis of biliary stones including gallstones (n = 66) and common bile duct (CBD) stones (n = 25) or spontaneously passing CBD stones (n = 11). The reference standard used was operative findings, endoscopic retrograde cholangiopancreatography or follow-up over 6 months. In DLCT, 120-kVp images, 40-keV virtual monoenergetic images and material decomposition images were created. We compared the diagnostic ability of DLCT and MRCP for biliary stones us...
Source: European Journal of Gastroenterology and Hepatology - December 2, 2020 Category: Gastroenterology Tags: Original Articles: Gastroenterology Source Type: research

The potential value of miRNA-223 as a diagnostic biomarker for Egyptian colorectal patients
Conclusion Circulating miRNA-223 can be a potential noninvasive prognostic biomarker for Egyptian CRC patients. (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - December 2, 2020 Category: Gastroenterology Tags: Original Articles: Gastroenterology Source Type: research

Incidence of metachronous gastric cancer after endoscopic submucosal dissection associated with eradication status of Helicobacter pylori
Conclusion: The treatment outcomes for EGC in the eradication group were favorable. The higher incidence of metachronous cancer in the eradication group suggests that careful endoscopic follow-up examinations are required. (Source: European Journal of Gastroenterology and Hepatology)
Source: European Journal of Gastroenterology and Hepatology - December 2, 2020 Category: Gastroenterology Tags: Original Articles: Gastroenterology Source Type: research

Is there an association between peptic ulcer disease and osteoporosis: a systematic review and cumulative analysis
Background Mounting studies have emerged indicating that patients with peptic ulcer disease (PUD) are at a high risk of developing osteoporosis, but the evidence has not been previously synthesized. The present study aims to examine whether patients with PUD have a significantly higher prevalence of osteoporosis than the healthy normal subjects. Methods Four electronic databases were systematically searched for eligible studies up to February 2020. The association between PUD and osteoporosis was evaluated by calculating the relative risk (RR) with a 95% confidence interval (CI). Results Six observational...
Source: European Journal of Gastroenterology and Hepatology - December 2, 2020 Category: Gastroenterology Tags: Review Articles Source Type: research