Fundoplication versus oral proton pump inhibitors for gastroesophageal reflux disease: a systematic review and meta-analysis of randomized clinical trials
AbstractGastroesophageal reflux disease (GERD) is a widely studied and highly prevalent condition. However, few are reported about the exact efficacy and safety of fundoplication (FPT) compared to oral intake proton-pump inhibitors (PPI). This systematic review and meta-analysis of randomized clinical trials (RCT) aims to compare PPI and FPT in relation to the efficacy, as well as the adverse events associated with these therapies. Search carried out in June 2020 was conducted on Medline, Cochrane, EMBASE and LILACS. Selection was restricted to RCT comparing PPI and FPT (open or laparoscopic) in GERD patients. Certainty of...
Source: Esophagus - February 2, 2021 Category: Gastroenterology Source Type: research
Comparison of the outcomes between total eversion and conventional triangulating stapling technique in cervical esophagogastric anastomosis after esophagectomy: a propensity score-matched analysis
ConclusionsThe incidence of anastomotic stenosis was significantly lower in the TE-TST group than in the C-TST group. TE-TST decreases the incidence of anastomotic stricture and can improve the quality of life in patients undergoing esophagectomy. (Source: Esophagus)
Source: Esophagus - February 1, 2021 Category: Gastroenterology Source Type: research
Predictive value of preoperative echocardiographic assessment for postoperative atrial fibrillation after esophagectomy for esophageal cancer
ConclusionsPreoperative echocardiographic evaluation is useful for predicting the onset of POAF after esophagectomy for esophageal cancer. Risk stratification using LAD and E/e ′ enables clinicians to identify patients at high risk for POAF before esophagectomy. (Source: Esophagus)
Source: Esophagus - January 29, 2021 Category: Gastroenterology Source Type: research
Diagnostic yield of conventional endoscopy with endoscopic ultrasonography for submucosal invasion of superficial esophageal squamous cell carcinoma: a post hoc analysis of multicenter prospective confirmatory study (JCOG0508)
ConclusionsWhile the accurate depth diagnosis in cSM ESCC was difficult to make, the clinical diagnosis of SM2 with both conventional endoscopy and EUS was significantly associated with pSM. Furthermore, diagnostic ER could be recommended to confirm the pathological diagnosis especially in cSM1 lesions with both conventional endoscopy and EUS. (Source: Esophagus)
Source: Esophagus - January 28, 2021 Category: Gastroenterology Source Type: research
Validity of endoscopic resection for clinically diagnosed T1a-MM/T1b-SM1 N0 M0 esophageal squamous cell carcinoma
ConclusionER is the first-line treatment for cMM/SM1 cancers with ≤ 3/4 circumferential extent considering that 59% of cMM/SM1 cancers were low-risk cancers for which ER is mostly curative. ER is not recommended for whole circumferential cMM/SM1 cancers given the low proportion of low-risk cancers and the high risk of stricture after ER. (Source: Esophagus)
Source: Esophagus - January 21, 2021 Category: Gastroenterology Source Type: research
Supplemental enteral tube feeding nutrition after hospital discharge of esophageal cancer patients who have undergone esophagectomy
ConclusionsOur results showed that routine use of 90-day home supplemental enteral tube feeding nutrition after hospital discharge for esophagectomy patients was both feasible and acceptable.Trial registrationUMIN000016286. (Source: Esophagus)
Source: Esophagus - January 21, 2021 Category: Gastroenterology Source Type: research
A comparative study of the lengths of different reconstruction routes used after thoracic esophagectomy
ConclusionThe retrosternal route was the shortest for esophageal reconstruction in living Japanese patients. (Source: Esophagus)
Source: Esophagus - January 19, 2021 Category: Gastroenterology Source Type: research
Optimization of robot-assisted thoracoscopic esophagectomy in the lateral decubitus position
ConclusionsCamera rotation and manual hand control assignment during RATE in the LDP reproduced the surgical view and manipulation of open esophagectomy and TE in the LDP. The robotic platform enabled meticulous dissection and reduced blood loss, but was initially time-consuming. Optimization of the port arrangement minimized operative duration. (Source: Esophagus)
Source: Esophagus - January 16, 2021 Category: Gastroenterology Source Type: research
Efficacy of endoscopic filling with polyglycolic acid sheets and fibrin glue for anastomotic leak after esophageal cancer surgery: identification of an optimal technique
ConclusionsEndoscopic filling with PGA sheets and fibrin glue is a safe and effective treatment for the closure of an anastomotic leak. The pre-soak method can achieve successful endoscopic filling. (Source: Esophagus)
Source: Esophagus - January 8, 2021 Category: Gastroenterology Source Type: research
Outcome of chemoradiotherapy using intensity-modulated radiation therapy for cervical esophageal cancer: a single institute experience
ConclusionsChemoradiotherapy using intensity-modulated radiation therapy for locally advanced cervical esophageal carcinoma achieved satisfactory locoregional control and survival with acceptable toxicities. (Source: Esophagus)
Source: Esophagus - January 8, 2021 Category: Gastroenterology Source Type: research
Feasibility and effectiveness of multi-injection thoracic paravertebral block via the intrathoracic approach for analgesia after thoracoscopic-laparoscopic esophagectomy
ConclusionsMulti-injection TPB via the intrathoracic approach under thoracoscopic direct vision is easy to perform and can effectively alleviate postoperative pain after TLE with fewer adverse reactions and contributing to improved postoperative recovery. (Source: Esophagus)
Source: Esophagus - January 6, 2021 Category: Gastroenterology Source Type: research
Peroral endoscopic myotomy as treatment for Zenker ’s diverticulum (Z-POEM): a multi-center international study
ConclusionZ-POEM is a safe and effective modality for managing ZD. (Source: Esophagus)
Source: Esophagus - January 2, 2021 Category: Gastroenterology Source Type: research
Effects of coexisting upper gastrointestinal symptoms on daily life and quality of life in patients with gastroesophageal reflux disease symptoms
ConclusionCoexisting FD symptoms, particularly atypical FD symptoms, had a large influence on the impairments of daily life and decreases in QOL. Daily medical care of GERD requires attention to coexisting symptoms and their treatment instead of just focusing on the chief complaints by patients. (Source: Esophagus)
Source: Esophagus - January 2, 2021 Category: Gastroenterology Source Type: research
Clinical features of idiopathic esophageal perforation compared with typical post-emetic type: a newly proposed subtype in Boerhaave ’s syndrome
ConclusionThis study first focused on the characteristics of idiopathic esophageal perforation that have been included in so-called Boerhaave ’s syndrome. The pathophysiology of the idiopathic type should be separately understood from post-emetic type, because the diagnostic and prognostic features largely differ. (Source: Esophagus)
Source: Esophagus - January 1, 2021 Category: Gastroenterology Source Type: research
Efficacy of vonoprazan 10 mg compared with 20 mg for the initial treatment in patients with erosive esophagitis: a randomized pilot study
ConclusionOur findings suggest that initial treatment with vonoprazan 10 mg might be useful especially in patients with mild erosive esophagitis. Large controlled studies are warranted to confirm our investigation. (Source: Esophagus)
Source: Esophagus - November 21, 2020 Category: Gastroenterology Source Type: research
