Tumor-infiltrating plasma cells are the promising prognosis marker for esophageal squamous cell carcinoma
ConclusionThis study revealed that high TIP in ESCC was associated with positive regulation of adaptive immunity and anti-tumor activity. (Source: Esophagus)
Source: Esophagus - March 10, 2021 Category: Gastroenterology Source Type: research
Circulating tumor cells after neoadjuvant chemotherapy are related with recurrence in esophageal squamous cell carcinoma
ConclusionsQuantitative and qualitative analysis of CTCs may provide useful complementary predictive and prognostic information in ESCC. (Source: Esophagus)
Source: Esophagus - March 4, 2021 Category: Gastroenterology Source Type: research
Histological changes in the human esophagus following triamcinolone injection to prevent esophageal stricture after endoscopic submucosal dissection
ConclusionsHistological finding of thinning of the subepithelial fibrous tissue of ESD ulcer scar in the human esophagus after TA injection was obtained. This suggests that TA suppresses the proliferation of the fibrous tissue of the subepithelial layer to help prevent esophageal stricture after widespread ESD in the human esophagus. (Source: Esophagus)
Source: Esophagus - March 2, 2021 Category: Gastroenterology Source Type: research
Early detection of anastomotic leakage after esophagectomy using drain amylase levels
ConclusionsCervical drain fluid amylase levels can be a useful screening method for early detection of AL after esophagectomy for esophageal cancer and may help reduce incidence of severe postoperative AL. (Source: Esophagus)
Source: Esophagus - February 28, 2021 Category: Gastroenterology Source Type: research
Performance of a deep learning-based identification system for esophageal cancer from CT images
ConclusionsOur AI-based diagnostic system succeeded in detecting esophageal cancer with high accuracy. More training with vast datasets collected from multiples centers would lead to even higher diagnostic accuracy and aid better decision making. (Source: Esophagus)
Source: Esophagus - February 26, 2021 Category: Gastroenterology Source Type: research
Clinical features and risk factors of gastric cancer detected by esophagogastroduodenoscopy in esophageal cancer patients
ConclusionsThe incidence rates of synchronous and metachronous gastric cancer with esophageal cancer were both over 5%. Careful endoscopic observation is required for moderate and severe atrophic gastritis at detecting concomitant gastric cancer in esophageal cancer patients. (Source: Esophagus)
Source: Esophagus - February 25, 2021 Category: Gastroenterology Source Type: research
Esophageal cancer patients' survival after complete response to definitive chemoradiotherapy: a retrospective analysis
ConclusionsA quarter of patients developed recurrent disease, mostly locoregional, after complete response. Complete response patients with originally advanced stage disease had fair clinical outcomes; salvage treatments after locoregional recurrence achieved modest long-term survival. (Source: Esophagus)
Source: Esophagus - February 24, 2021 Category: Gastroenterology Source Type: research
Evaluation of subcarinal lymph node dissection and metastasis in transmediastinal radical esophagectomy
ConclusionsSubcarinal lymph nodes can be dissected in transmediastinal esophagectomy, almost equivalent to transthoracic esophagectomy. The tumor size, depth, and location may be predictive factors for subcarinal lymph node metastasis. (Source: Esophagus)
Source: Esophagus - February 18, 2021 Category: Gastroenterology Source Type: research
Feasibility of enhanced recovery protocol in minimally invasive McKeown esophagectomy
ConclusionsThis study shows that the promotion of an enhanced recovery protocol in minimally invasive McKeown esophagectomy maintains nutritional status without increasing postoperative complications. (Source: Esophagus)
Source: Esophagus - February 18, 2021 Category: Gastroenterology Source Type: research
The duration of systemic inflammatory response syndrome is a reliable indicator of long-term survival after curative esophagectomy for esophageal squamous cell carcinoma
ConclusionSIRS duration is a more reliable prognostic marker than the development of pneumonia and high postoperative CRP value after surgery for ESCC. The surgeons should aim to reduce the SIRS duration to improve the prognosis of ESCC patients. (Source: Esophagus)
Source: Esophagus - February 16, 2021 Category: Gastroenterology Source Type: research
Gastric dysrhythmia in gastroesophageal reflux disease: a systematic review and meta-analysis
ConclusionsConsistent abnormalities in gastric slow-wave activity, as measured by EGG, were identified in adults with GERD. Further investigation into these abnormalities using novel emerging electrophysiology techniques is desirable, to better define their contribution toward GERD pathophysiology. (Source: Esophagus)
Source: Esophagus - February 16, 2021 Category: Gastroenterology Source Type: research
Stimulated saliva secretion is reduced in proton pump inhibitor-resistant severe reflux esophagitis patients
ConclusionStimulated saliva secretion was reduced in PPI-resistant severe reflux esophagitis patients. (Source: Esophagus)
Source: Esophagus - February 15, 2021 Category: Gastroenterology Source Type: research
PDZK1 induces resistance to apoptosis in esophageal adenocarcinoma cells
ConclusionOverexpression of PDZK1 protein induces an apoptosis-resistant phenotype in BE cells, which may be a potential therapeutic target. (Source: Esophagus)
Source: Esophagus - February 14, 2021 Category: Gastroenterology Source Type: research
The role of adjuvant chemotherapy in esophageal cancer patients after neoadjuvant chemotherapy plus surgery
ConclusionsAC may offer a significant additional benefit to the prognosis of esophageal cancer patients who have many positive lymph nodes even after NAC. (Source: Esophagus)
Source: Esophagus - February 12, 2021 Category: Gastroenterology Source Type: research
Surgical treatment of esophageal cancer with anomaly of the aortic arch and its branches
ConclusionFor resectable esophageal cancer combined with aortic arch and its branches anomalies, satisfactory surgical results can be obtained under careful preoperative evaluation and reasonable surgical approach selection. (Source: Esophagus)
Source: Esophagus - February 4, 2021 Category: Gastroenterology Source Type: research
