Among females older than 50 years, saliva secretion is significantly lower in non-erosive reflux disease patients than in healthy controls
ConclusionAmong females older than 50 years, saliva secretion was significantly lower in NERD patients than in HC. This reduction in saliva secretion may contribute to the pathophysiology of NERD in females. (Source: Esophagus)
Source: Esophagus - October 16, 2023 Category: Gastroenterology Source Type: research
Comparison of the subtotal and narrow gastric conduit for cervical esophagogastrostomy after esophagectomy in esophageal cancer patients: a propensity score-matched analysis
ConclusionsIn cervical circular-stapled esophagogastrostomy after esophagectomy, SGC was superior to NGC in terms of reducing the risk of anastomotic leakage, although the risk of anastomotic stricture needs to be resolved. (Source: Esophagus)
Source: Esophagus - October 13, 2023 Category: Gastroenterology Source Type: research
Is it meaningful to add mesh reinforcement to laparoscopic fundoplication for esophageal hiatal hernias in the patients with high risk of hiatal hernia recurrence?
ConclusionsMesh reinforcement in laparoscopic fundoplication for esophageal hiatal hernias contributes to preventing the recurrence of esophageal hiatal hernias when it comes to patient options based on these criteria. (Source: Esophagus)
Source: Esophagus - October 10, 2023 Category: Gastroenterology Source Type: research
Type B2 vessels and infiltrative growth patterns b and c are associated with lymphatic invasion in pT1a-lamina propria mucosa esophageal squamous cell carcinoma
ConclusionsThe tumor growth pattern of pT1a-LPM ESCC was mostly INF-a in type B1 patterns. Type B2 patterns are rarely present in pT1a-LPM ESCC, however lymphatic invasion with INF-b or INF-c was frequently observed. Careful observation before endoscopic resection with NBI-ME is important to identify B2 patterns to predict histopathology. (Source: Esophagus)
Source: Esophagus - September 11, 2023 Category: Gastroenterology Source Type: research
Impact of pulmonary vein anatomy and left atrial size on postoperative atrial fibrillation after esophagectomy for esophageal cancer
ConclusionIncidence of POAF after esophagectomy was related to both left atrial enlargement and common left pulmonary vein assessed by preoperative MDCT. Additional analysis of atrial size and pulmonary vein variation would facilitate preoperative assessment of the risk of POAF, but future studies must ascertain therapeutic strategy. (Source: Esophagus)
Source: Esophagus - September 11, 2023 Category: Gastroenterology Source Type: research
The feasibility of post-photodynamic therapy salvage esophagectomy in patients with esophageal squamous cell carcinoma treated with definitive chemoradiotherapy
ConclusionsAlthough salvage esophagectomy after PDT carries certain risks, patients who achieved an R0 had a promising long-term prognosis. The location and size of the lesion may be critical factors in determining whether R0 can be achieved with salvage esophagectomy after PDT. (Source: Esophagus)
Source: Esophagus - September 11, 2023 Category: Gastroenterology Source Type: research
Concurrent chemoradiotherapy using proton beams can reduce cardiopulmonary morbidity in esophageal cancer patients: a systematic review
AbstractThis systematic review was performed to investigate the superiority of proton beam therapy (PBT) to photon-based radiotherapy (RT) in treating esophageal cancer patients, especially those with poor cardiopulmonary function. The MEDLINE (PubMed) and ICHUSHI (Japana Centra Revuo Medicina) databases were searched from January 2000 to August 2020 for studies evaluating one end point at least as follows; overall survival, progression-free survival, grade ≥ 3 cardiopulmonary toxicities, dose-volume histograms, or lymphopenia or absolute lymphocyte counts (ALCs) in esophageal cancer patients treated with PBT or photon-b...
Source: Esophagus - September 11, 2023 Category: Gastroenterology Source Type: research
Analysis of the short-term outcomes after esophagectomy for esophageal cancer during the COVID-19 pandemic using data from a nationwide Japanese database
ConclusionsEsophagectomy was performed during the pandemic despite limited medical resources by a systematic endeavor of the entire surgical department in Japan, without increasing the incidence rate of worse outcome. (Source: Esophagus)
Source: Esophagus - September 11, 2023 Category: Gastroenterology Source Type: research
Ramelteon and suvorexant for postoperative delirium in elderly patients with esophageal cancer
ConclusionsRamelteon and suvorexant may play an important role in reducing postoperative delirium in elderly patients with esophageal cancer. (Source: Esophagus)
Source: Esophagus - August 10, 2023 Category: Gastroenterology Source Type: research
Usefulness of the aldehyde breath test for predicting metachronous recurrence in patients with esophageal squamous cell carcinoma and hypopharyngeal squamous cell carcinoma
ConclusionsThe acetaldehyde-to-ethanol ratio detected using the acetaldehyde breath test could be a novel biomarker of metachronous recurrence after endoscopic submucosal dissection in patients with esophageal squamous cell carcinoma and hypopharynx squamous cell carcinoma.Trial registration numberUMIN000040615. (Source: Esophagus)
Source: Esophagus - August 8, 2023 Category: Gastroenterology Source Type: research
Different gastric tubes in esophageal reconstruction during esophagectomy
This article will review the progress and clinical application status of different types of gastric grafts from the perspectives of preparation methods, studies of anatomy and perioperative outcomes, existing problems and future outlook. (Source: Esophagus)
Source: Esophagus - July 25, 2023 Category: Gastroenterology Source Type: research
Proposal for T3 classification of esophagogastric junction carcinoma based on the interconnection of extramural anatomical structures
AbstractClassification of extramural invasion of esophagogastric junction carcinoma (EGJC) is not yet established. The anatomy surrounding the EGJ alters between the mediastinum and the abdominal cavity. This review proposed a T3 classification of EGJC based on anatomical continuity. Analysis of endoscopic ultrasound images, review of intraoperative images, and detailed observation of surgical specimens were followed by a review of the literature. In the EGJ, the muscularis propria of the esophagus is enclosed in mediastinal adipose tissue called the adventitia, which is surrounded by the diaphragmatic crus and contains th...
Source: Esophagus - July 20, 2023 Category: Gastroenterology Source Type: research
Esophageal replacement when stomach conduit is unavailable: is colon the best option?
(Source: Esophagus)
Source: Esophagus - July 19, 2023 Category: Gastroenterology Source Type: research
Impact of MRI on the post-therapeutic diagnosis of T4 esophageal cancer
ConclusionsOur results —with reference to the pathological diagnosis—revealed that MRI had a superior diagnostic performance to CT for diagnosing T4b esophageal cancer invading the surrounding organs. An accurate diagnosis of T4b esophageal cancer may facilitate the implementation of appropriate treatment strategies. (Source: Esophagus)
Source: Esophagus - May 26, 2023 Category: Gastroenterology Source Type: research
Clinical predictors of early postoperative recurrence after radical esophagectomy for thoracic esophageal cancer
ConclusionsEarly recurrence of thoracic esophageal cancer (i.e., during ≤ 6 months after esophagectomy) was associated with higher initial tumor marker levels and pathological findings of v ≥ 2. The combination of these two factors is useful as a simple and critical predictor of early postoperative recurrence. (Source: Esophagus)
Source: Esophagus - May 24, 2023 Category: Gastroenterology Source Type: research
