Annual banned ‐substance review 16th edition—Analytical approaches in human sports drug testing 2022/2023
AbstractIn this 16th edition of the annual banned-substance review on analytical approaches in human sports drug testing, literature on recent developments in this particular section of global anti-doping efforts that was published between October 2022 and September 2023 is summarized and discussed. Most recent additions to the continuously growing portfolio of doping control analytical approaches and investigations into analytical challenges in the context of adverse analytical findings are presented, taking into account existing as well as emerging challenges in anti-doping, with specific focus on substances and methods ...
Source: Drug Testing and Analysis - November 21, 2023 Category: Drugs & Pharmacology Authors: Mario Thevis,
Tiia Kuuranne,
Hans Geyer Tags: REVIEW ARTICLE Source Type: research
Ultraviolet spectra determination and computational analysis of 44 E/Z steroid isomers in dried blood spot
This study for the first time provides a method to tentatively identify the 44 E/Z configurations of steroid oxime products. (Source: Drug Testing and Analysis)
Source: Drug Testing and Analysis - November 14, 2023 Category: Drugs & Pharmacology Authors: Xiya Yan,
Siyu Yan,
Wei Chang,
Chao Wen,
Lisi Zhang,
Zhanliang Wang,
Sheng Yang Tags: RESEARCH ARTICLE Source Type: research
Detection of doping control sample substitutions via single nucleotide polymorphism ‐based ID typing
The authenticity of a doping control sample is a key element of sports drug testing programs. To determine attempts of manipulations by sample swapping, the utility of a single nucleotide polymorphism (SNP)-based sample authentication with a multi-target SNP panel was assessed. Urine (8 ml) and DBS (20 μl) test samples were reliably typed and matched to whole blood reference samples and robust profiling of urine doping control specimens was confirmed with an assay input of 12 ml. AbstractThe authenticity of a doping control sample is a key element of sports drug testing programmes. Doping control sample manipulation by pr...
Source: Drug Testing and Analysis - November 13, 2023 Category: Drugs & Pharmacology Authors: Nana Naumann,
Katja Walpurgis,
Ana Rubio,
Andreas Thomas,
Alina Pa ßreiter,
Mario Thevis Tags: SPECIAL ISSUE ‐ RESEARCH ARTICLE Source Type: research
Detection of selective androgen receptor modulator YK ‐11 in a doping control sample
(Source: Drug Testing and Analysis)
Source: Drug Testing and Analysis - November 10, 2023 Category: Drugs & Pharmacology Authors: Tim Sobolevsky,
Yulia Kucherova,
Brian Ahrens Tags: CASE REPORT Source Type: research
Dried blood spots for erythropoietin analysis: Detection of micro ‐doses, EPO c.577del variant and comparison with in‐competition matching urine samples
In conclusion, this work demonstrated that DBS can be a useful complementary matrix to urine samples for EPO detection. (Source: Drug Testing and Analysis)
Source: Drug Testing and Analysis - November 9, 2023 Category: Drugs & Pharmacology Authors: Carmel E. Heiland,
Laurent Martin,
Xinmiao Zhou,
Lisi Zhang,
Magnus Ericsson,
Alexandre Marchand Tags: SHORT COMMUNICATION Source Type: research
The 41st Manfred Donike workshop on doping analysis
(Source: Drug Testing and Analysis)
Source: Drug Testing and Analysis - November 8, 2023 Category: Drugs & Pharmacology Authors: Mario Thevis Tags: EDITORIAL Source Type: research
Comparison of poisoning deaths with wastewater ‐based consumption estimates and assessment of fatal toxicity for amphetamine‐type stimulant drugs
In this study, we aimed to compare temporal trends with respect to amphetamine, methamphetamine and methylenedioxymethamphetamine (MDMA) revealed by these indicators and explore the differences in fatal toxicity between the stimulants. All deaths in which poisoning caused by amphetamine, methamphetamine or MDMA was either the underlying or contributing cause of death in Finland in 2012, 2014, 2016, 2018 and 2020 were included in the study. Consumption of the studied drugs was measured by WBE in the same years. There was a significant correlation between poisoning and drug consumption for all three stimulants, and for amphe...
Source: Drug Testing and Analysis - November 7, 2023 Category: Drugs & Pharmacology Authors: Pirkko Kriikku,
Aino Kankaanp ää,
Teemu Gunnar,
Ilkka Ojanperä Tags: RESEARCH ARTICLE Source Type: research
