Comorbidity and Therapeutic Approaches in Patients with Necrobiosis Lipoidica
Conclusion: Therapeutic options were chosen individually in accordance with the severity of NL and presence of ulceration. Topical calcineurin inhibitors, systemic application of fumaric acid esters, and dapsone represent effective alternatives to the use of steroids.Dermatology (Source: Dermatology)
Source: Dermatology - April 7, 2021 Category: Dermatology Source Type: research

Off-Label Use and Safety of Drug Use in Vascular Anomalies
Conclusions: Off-label drug use in VA is the rule and not the exception. Significant safety concerns are common. It is necessary to carefully weigh risk and benefits for every patient when using systemic and local treatments carrying safety concerns. Patients should be openly informed and involved in the decision-making process.Dermatology (Source: Dermatology)
Source: Dermatology - April 6, 2021 Category: Dermatology Source Type: research

Temporal Variation in < b > < i > Staphylococcus aureus < /i > < /b > Protein A Genotypes from Nose and Skin in Atopic Dermatitis Patients
Conclusion:S. aureus strains in AD are highly heterogeneous between patients. The majority of patients carry the samespa-type in the nose and skin without temporal variation, suggesting clonal colonization within individual patients. No predominantspa-type or temporal variation is associated with increased disease severity.Dermatology (Source: Dermatology)
Source: Dermatology - April 6, 2021 Category: Dermatology Source Type: research

Barriers to Diversity and Academic Promotion in Dermatology: Recommendations Moving Forward
Dermatology (Source: Dermatology)
Source: Dermatology - April 6, 2021 Category: Dermatology Source Type: research

Calcium Electroporation for Keloids: A First-in-Man Phase I Study
Conclusion: In this first phase I clinical study on calcium electroporation for keloids, treatment was found to be safe with minor side effects. Overall, patients experienced symptom relief, and in some patients keloid thickness was reduced.Dermatology (Source: Dermatology)
Source: Dermatology - March 31, 2021 Category: Dermatology Source Type: research

Melanoma of the Nail Apparatus: An Analysis of Patients ’ Survival and Associated Factors
Conclusion: Primary tumor location in the hand and lower tumor thickness might be correlated with better patients ’ survival. The study results suggest that total amputation might not be necessary in all NAM cases.Dermatology (Source: Dermatology)
Source: Dermatology - March 31, 2021 Category: Dermatology Source Type: research

The Spread of Resistant Tinea and the Ingredients of a Perfect Storm
Dermatology (Source: Dermatology)
Source: Dermatology - March 31, 2021 Category: Dermatology Source Type: research

The Usefulness of Dermoscopy for the Recognition of Malignant Collision Tumors
Conclusions: The diagnosis of MCT can be assisted and clarified by dermoscopy. However, many of these lesions manifest complex morphologies and continue to be challenging, even for experts on dermoscopy. Atypical, uncertain, or non-classifiable lesions still need a complete excision for the final diagnosis.Dermatology (Source: Dermatology)
Source: Dermatology - March 31, 2021 Category: Dermatology Source Type: research

Are Dermatology Systematic Reviews Spinning Out of Control?
Dermatology (Source: Dermatology)
Source: Dermatology - March 30, 2021 Category: Dermatology Source Type: research

Mucosal Respiratory Syndrome: A Systematic Literature Review
Background:Mycoplasma pneumoniae atypical pneumonia is frequently associated with erythema multiforme. Occasionally, a mycoplasma infection does not trigger any cutaneous but exclusively mucosal lesions. The term mucosal respiratory syndrome is employed to denote the latter condition. Available reviews do not address the possible association of mucosal respiratory syndrome with further atypical bacterial pathogens such asChlamydophila pneumoniae,Chlamydophila psittaci,Coxiella burnetii,Francisella tularensis, orLegionella species. We therefore performed a systematic review of the literature addressing this issue in the Nat...
Source: Dermatology - March 26, 2021 Category: Dermatology Source Type: research

Association between Hidradenitis Suppurativa and Inflammatory Arthritis: A Systematic Review and Meta-Analysis
Conclusions: Our findings show that HS patients have a 3-fold increased risk of developing inflammatory arthritis. HS patients are specifically at a higher risk for spondyloarthritis, its subtype AS, and RA.Dermatology (Source: Dermatology)
Source: Dermatology - March 26, 2021 Category: Dermatology Source Type: research

Beh çet’s Disease Is Associated with Multiple Sclerosis and Rheumatoid Arthritis: A Korean Population-Based Study
Conclusion: Our results suggest that BD is associated with multiple sclerosis and rheumatoid arthritis.Dermatology (Source: Dermatology)
Source: Dermatology - March 23, 2021 Category: Dermatology Source Type: research

Implementing Medical Chatbots: An Application on Hidradenitis Suppurativa
Conclusions: A medical chatbot has to be customised to the specific subject whilst general principles have to be considered. High-quality information has to be available in just a few clicks. People concerned about HS are looking for a diagnosis online and often have not seen a doctor previously. Guidance towards appropriate care should be provided.Dermatology (Source: Dermatology)
Source: Dermatology - March 19, 2021 Category: Dermatology Source Type: research

Bidirectional Association between Psoriasis and Atopic Dermatitis: A Nationwide Population-Based Cohort Study
Conclusion: Our study demonstrated a bidirectional association between psoriasis and atopic dermatitis, suggesting that psoriasis and atopic dermatitis are not mutually exclusive and may share some biological mechanisms.Dermatology (Source: Dermatology)
Source: Dermatology - March 18, 2021 Category: Dermatology Source Type: research

Biological Therapies for Atopic Dermatitis: A Systematic Review
Conclusion: The biological therapies with the most robust evidence on efficacy and long-term safety for AD treatment include dupilumab, barcitinib, abrocitinib, and delgocitinib. Most of the biologics mentioned in this review were still at the exploratory stage. This review will help practitioners advise patients seeking suitable biological therapies and offer experimental study directions for treatment.Dermatology (Source: Dermatology)
Source: Dermatology - March 18, 2021 Category: Dermatology Source Type: research