Letter to the Editor with Reference to “The Efficacy and Safety of Topical β-Blockers in Treating Infantile Hemangiomas: A Meta-Analysis Including 11 Randomized Controlled Trials”
Dermatology (Source: Dermatology)
Source: Dermatology - May 12, 2022 Category: Dermatology Source Type: research
Do Patients with Psoriatic Arthritis Have More Severe Skin Disease than Patients with Psoriasis Only? A Systematic Review and Meta-Analysis
Background: Early identification of patients at risk of psoriatic arthritis (PsA) is essential to facilitate early diagnosis and improve clinical outcomes. Severe cutaneous psoriasis has been proposed to be associated with PsA, but a recent assessment of the evidence is lacking. Therefore, in this systematic review, we address the association of psoriasis skin severity with the presence and development of PsA.Summary: We included articles from a review published in 2014 and supplemented these with recent literature by performing an additional systematic search to identify studies published between 1 January 2013 and 11 Feb...
Source: Dermatology - May 12, 2022 Category: Dermatology Source Type: research
Looking at Interleukin-22 from a New Dermatological Perspective: From Epidermal Homeostasis to Its Role in Chronic Skin Diseases
Twenty years after the cloning, characterization, and identification of interleukin (IL)-22 in 2000, the precise biological role of this cytokine in healthy and unhealthy skin is not completely known. The aim of this review is to provide an overview on the recent knowledge available in literature about the origin, sources, targets, molecular mechanism of action, and clinical issues regarding IL-22. Last but not least, recent experimental evidence obtained in a 3D model of organotypic culture of normal human skin highlights its homeostatic role and will be discussed in detail, as personal observations. As most of the data c...
Source: Dermatology - May 10, 2022 Category: Dermatology Source Type: research
HautTief Multidisciplinary Educational Program for Patients with Psoriasis or Atopic Dermatitis: A Randomized Controlled Study
Conclusion: An educational program may improve HRQoL and depression status of patients with psoriasis or AD.Dermatology (Source: Dermatology)
Source: Dermatology - May 9, 2022 Category: Dermatology Source Type: research
Tattoo Ink Market in France: A Field Study among 598 Professional Tattooists
Conclusions: The market of tattoo inks in France is dominated only by a fistful of brands. Controls by official authorities should target those popular brands, even though all brands should respect the law. Toxicological studies should always precise the provenance market and which brands are tested, so we can assess their impact in real life. Tattooists should also try to lower the number of ready-made colors they require.Dermatology (Source: Dermatology)
Source: Dermatology - May 9, 2022 Category: Dermatology Source Type: research
Diagnostic Accuracy of Digital Staining ex vivo Confocal Microscopy for Diagnosing and Subtyping Basal Cell Carcinoma in Fresh Pretherapeutic Punch Biopsies: A Monocentric Prospective Study
Conclusions: These results render EVCM as a promising option for “real-time” pretreatment evaluation of clinically suspected BCC lesions. Further larger randomized studies are needed to assess the efficiency of EVCM versus standard care in patients with clinically suspected BCC.Dermatology (Source: Dermatology)
Source: Dermatology - May 5, 2022 Category: Dermatology Source Type: research
Examination of Subungual Hematomas and Subungual Melanocytic Lesions by Using Optical Coherence Tomography and Dermoscopy
Conclusion: Our findings indicate that the use of OCT in addition to dermoscopy provides high-resolution optical imaging information for the diagnosis of subungual hematoma and facilitates the differential diagnosis of subungual hematomas and subungual melanocytic lesions.Dermatology (Source: Dermatology)
Source: Dermatology - May 4, 2022 Category: Dermatology Source Type: research
Intralesional Treatments in Hidradenitis Suppurativa: A Systematic Review
In conclusion, IL treatments such as corticosteroid injections and light-based therapies seem to be effective and safe for both acute inflammatory lesions and fistulas, although more prospective studies, with higher sample sizes and with standardized outcomes are needed to provide more scientific evidence on the subject.Dermatology (Source: Dermatology)
Source: Dermatology - April 27, 2022 Category: Dermatology Source Type: research
Occupational Chronic Contact Dermatitis Successfully Treated with Dupilumab: A Case Series
Conclusions: We report a case series of atopic and nonatopic workers with occupational chronic contact dermatitis who failed to achieve remission under various systemic modalities but did so using dupilumab. We suggest considering dupilumab treatment for recalcitrant occupational contact dermatitis.Dermatology (Source: Dermatology)
Source: Dermatology - April 22, 2022 Category: Dermatology Source Type: research
Self-Assessment Questionnaire on Patient-Physician Concordance on Nevus Self-Count and Models Development to Predict High-Risk Phenotype & #x3e;50 Nevi
Conclusions: Patients were partially able to provide correct estimation of their whole-body nevus self-count. The item nevi on the back seems to be the first and most important predictor of TBNC #x3e;50 across our models. Delivery of high-sensitivity and high-specificity prediction models based on our questionnaire item combination may help defining a high-risk target population.Dermatology (Source: Dermatology)
Source: Dermatology - April 22, 2022 Category: Dermatology Source Type: research
Pathways from Diagnosis to Death from Keratinocyte Cancer in Kidney Transplant Recipients
Conclusion: Fatal keratinocyte cancers overwhelmingly arise on the head and neck, with lungs the most common metastasis site. The short time from diagnosis of primary to death indicates the aggressive nature of these keratinocyte cancers.Dermatology (Source: Dermatology)
Source: Dermatology - April 19, 2022 Category: Dermatology Source Type: research
Non-Atopic Chronic Nodular Prurigo (Prurigo Nodularis Hyde): A Systematic Review of Best-Evidenced Treatment Options
Background: Chronic nodular prurigo (CNPG) is a chronic, inflammatory skin disease, characterized by intense and debilitating pruritus. The pathophysiology is not fully understood, and the condition is difficult to treat with no targeted therapies. The aim of this systematic review was to review the evidence of therapies for non-atopic CNPG and conduct a meta-analysis of the results.Summary: We conducted a systematic review of the literature concerning effect of treatment for non-atopic CNPG. Due to few randomized controlled trials (RCTs) and case series, the literature was unfortunately too sparse to conduct a meta-analys...
Source: Dermatology - April 13, 2022 Category: Dermatology Source Type: research
Dermoscopic Features of Actinic Cheilitis and Other Common Inflammatory Cheilitis: A Multicentric Retrospective Observational Study by the International Dermoscopy Society
Conclusion: Despite differences in the frequency of mucoscopic structures, we have not found pathognomonic features allowing for differentiation between analyzed variants of cheilitis.Dermatology (Source: Dermatology)
Source: Dermatology - April 7, 2022 Category: Dermatology Source Type: research
Ocular Abnormalities in Patients with Vitiligo: A Systematic Review and Meta-Analysis
Conclusions: Our study supports an association between dry eye and thinner subfoveal choroidal thickness in patients with vitiligo. Dermatologists should be aware of these possible comorbidities and refer vitiligo patients with ocular symptoms to ophthalmologists for further management.Dermatology (Source: Dermatology)
Source: Dermatology - April 4, 2022 Category: Dermatology Source Type: research
Differences by Anatomical Site of Non-Acral Lentiginous Melanomas of the Lower Limb
Conclusion: Melanoma development in foot is less related to sun exposure and is associated with pathological features that can account for the worse prognosis and poorer survival.Dermatology (Source: Dermatology)
Source: Dermatology - March 29, 2022 Category: Dermatology Source Type: research
