Hematological Inflammatory Markers in Patients with Pemphigus Vulgaris
Conclusion: Our results suggest that the neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, platelet-to-neutrophil ratio, and mean platelet volume can be useful markers for monitoring treatment response, while the neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio can also assist in detecting early relapse.Dermatology (Source: Dermatology)
Source: Dermatology - January 20, 2021 Category: Dermatology Source Type: research

Predictive Factors of Non-Response to Vismodegib in Locally Advanced Basal-Cell Carcinoma
Conclusion: In this study, non-response of laBCC to vismodegib therapy was associated with muscle involvement. Previous radiotherapy and intermittent use of vismodegib have been identified as causes favoring non-response to vismodegib. Due to the low numbers of patients included in the study, it is difficult to draw firm conclusions. Further studies are needed to confirm these data.Dermatology (Source: Dermatology)
Source: Dermatology - January 20, 2021 Category: Dermatology Source Type: research

Adherence to Primary Prevention and Skin Self-Examination Practices by Spanish Melanoma Patients
Conclusion: Within the population of patients with melanoma, a high percentage of patients do not rigorously follow the recommended prevention measures. Our study highlights the need to implement awareness in this population to improve the prevention of cutaneous cancer.Dermatology (Source: Dermatology)
Source: Dermatology - January 19, 2021 Category: Dermatology Source Type: research

Understanding Hormonal Therapies: Overview for the Dermatologist Focused on Hair
This article reviews the specific properties of current estrogen- and progesterone-containing hormonal treatments and their implications for the patient with hair loss. The complexity of the task comes from the paucity of data and discrepancy in the literature on the effect of the specific hormonal-receptor activities.Dermatology (Source: Dermatology)
Source: Dermatology - January 19, 2021 Category: Dermatology Source Type: research

Hyperandrogenism, Insulin Resistance, and Acanthosis Nigricans (HAIR-AN) Syndrome Reflects Adipose Tissue Dysfunction ( “Adiposopathy” or “Sick Fat”) in Asian Indian Girls
Conclusion: The significantly raised adipocytokines in HAIR-AN syndrome patients as compared to PCOS patients indicates the primary role of adipose tissue dysfunction ( “adiposopathy”) in the pathogenesis of HAIR-AN syndrome while only a minor role, if any, in PCOS. Both these syndromes stand as distinct entities pathogenically with an overlapping phenotype.Dermatology (Source: Dermatology)
Source: Dermatology - January 14, 2021 Category: Dermatology Source Type: research