Mucosal Respiratory Syndrome: A Systematic Literature Review

Background:Mycoplasma pneumoniae atypical pneumonia is frequently associated with erythema multiforme. Occasionally, a mycoplasma infection does not trigger any cutaneous but exclusively mucosal lesions. The term mucosal respiratory syndrome is employed to denote the latter condition. Available reviews do not address the possible association of mucosal respiratory syndrome with further atypical bacterial pathogens such asChlamydophila pneumoniae,Chlamydophila psittaci,Coxiella burnetii,Francisella tularensis, orLegionella species. We therefore performed a systematic review of the literature addressing this issue in the National Library of Medicine, Excerpta Medica, and Web of Science databases.Summary: We found 63 patients ( ≤18 years,n = 36; #x3e;18 years,n = 27; 54 males and 9 females) affected by a mucosal respiratory syndrome. Fifty-three cases were temporally associated with aM. pneumoniae and 5 with aC. pneumoniae infection. No cases temporally associated withC. psittaci,C. burnetii,F. tularensis, orLegionella species infection were found. Two cases were temporally associated with Epstein-Barr virus or influenzavirus B, respectively.Dermatology
Source: Dermatology - Category: Dermatology Source Type: research