Combinatorial Chemistry and High Throughput Screening This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Integrated Serum Pharmacochemistry and Network Pharmacological Analysis Used To Explore Possible Anti-Aging Mechanisms of the Ginsenosides
CONCLUSION: The potential mechanisms of the anti-aging effect of ginsenosides involve multiple components, targets, and pathways. These findings serve as a foundation for further research into the processes behind ginsenoside's anti-aging impact.PMID:38441012 | DOI:10.2174/0113862073270652231115080745 (Source: Combinatorial Chemistry and High Throughput Screening)
Source: Combinatorial Chemistry and High Throughput Screening - March 5, 2024 Category: Chemistry Authors: Jing Li Ruigang Li Qing Yang Xiaoran Liu Xiaobo Qu Na Li Source Type: research

Unraveling Amentoflavone's Therapeutic Potential in Alzheimer's Disease: A Preclinical Assessment
Comb Chem High Throughput Screen. 2024 Mar 4. doi: 10.2174/0113862073301291240229102657. Online ahead of print.ABSTRACTAlzheimer's disease is one of the neurodegenerative diseases which causes cognition deficit. There are currently few medications available to treat Alzheimer's disease, even though researchers have devoted a great deal of time studying the condition and offering many benefits. Thus, only a few drugs are available for the treatment of Alzheimer's disease. Amentoflavone is a dietary component found in many plants and herbs that has several health advantages. Amentoflavone has demonstrated strong protective b...
Source: Combinatorial Chemistry and High Throughput Screening - March 5, 2024 Category: Chemistry Authors: Sushma Singh Neetu Agrawal Ahsas Goyal Source Type: research

Plant Adaptation and Tolerance to Heat Stress: Advance Approaches and Future Aspects
Comb Chem High Throughput Screen. 2024 Mar 4. doi: 10.2174/0113862073300371240229100613. Online ahead of print.ABSTRACTHeat stress impacts plant growth at all phases of development, although the particular threshold for heat tolerance varies significantly across different developmental stages. During seed germination, elevated temperatures can either impede or completely halt the process, contingent upon the plant type and the severity of the stress. During advanced stages, high temperatures can have a negative impact on photosynthesis, respiration, water balance, and membrane integrity. Additionally, they can also influen...
Source: Combinatorial Chemistry and High Throughput Screening - March 5, 2024 Category: Chemistry Authors: Vineeta Pandey Sonia Singh Source Type: research

Quercetin Prevents HSpertension in Dahl Salt-sensitive Rats Fed a High-salt Diet Through Balancing Endothelial Nitric Oxide Synthase and Sirtuin 1
CONCLUSION: Quercetin reduced blood pressure by enhancing the expression of SIRT1 and eNOS in Dahl SS rats fed a high-salt diet.PMID:38415447 | DOI:10.2174/0113862073284196240214082904 (Source: Combinatorial Chemistry and High Throughput Screening)
Source: Combinatorial Chemistry and High Throughput Screening - February 28, 2024 Category: Chemistry Authors: Guanji Wu Fuqiang Liu Qing Cui Tao Zhang Junjun Hao Jianjun Bao Source Type: research

Pharmacological Mechanisms of Kirenol against Ovarian Carcinoma: A Network Pharmacology and Experimental Validation Study In Vitro
CONCLUSION: In summary, the combined results of our network pharmacology analysis and in vitro tests emphasized that Kirenol hinders the growth of ovarian cancer cells, causes cell cycle arrest, enhances apoptosis, and hampers migration, possibly by regulating the PI3K/AKT/CDK4 signaling pathway.PMID:38415456 | DOI:10.2174/0113862073289977240216075724 (Source: Combinatorial Chemistry and High Throughput Screening)
Source: Combinatorial Chemistry and High Throughput Screening - February 28, 2024 Category: Chemistry Authors: Xiaoling Mao Hong Zhu Jun Gao Shixin Lin Yin Bao Mingyue Zhang Huan Yang Source Type: research

Is Ancient Medical Treatment an Option for Curating Osteosarcoma Combined with Chemotherapy? A Basic Analysis of Clinic Pharmacy
CONCLUSION: This study indicates that the mode of TCM combined with chemotherapy sheds light on the clinical treatment of OS, which is much better than the one-way mode.PMID:38409719 | DOI:10.2174/0113862073264769231116062123 (Source: Combinatorial Chemistry and High Throughput Screening)
Source: Combinatorial Chemistry and High Throughput Screening - February 27, 2024 Category: Chemistry Authors: Jian-Yu Hu Ya-Ru Gao Yu-Qi Bao Jing Zhao Bo Liu Chang-Wei Zhao Zheng-Yao Zhang Source Type: research