Combinatorial Chemistry and High Throughput Screening This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

The Mechanism of Action and Experimental Verification of Narenmandula in the Treatment of Postmenopausal Osteoporosis
CONCLUSION: The potential mechanism and efficacy of Narenmandula against PMOP may be related to the PI3K-AKT pathway.PMID:38178685 | DOI:10.2174/0113862073264965231116105323 (Source: Combinatorial Chemistry and High Throughput Screening)
Source: Combinatorial Chemistry and High Throughput Screening - January 5, 2024 Category: Chemistry Authors: Jirimutu Xiao Ziceng Yu Qiuge Han Yang Guo Jiapeng Ye Hua Lian Linning Wang Yong Ma Mengmin Liu Source Type: research

Differential miRNA Profiling Reveals miR-4433a-5p as a Key Regulator of Chronic Obstructive Pulmonary Disease Progression via PIK3R2- mediated Phenotypic Modulation
CONCLUSIONS: MiR-4433a-5p can be used as a marker and potential therapeutic target for the progression of COPD. As a target gene of miR-4433a-5p, PIK3R2 can affect the progression of COPD by regulating phenotypes, such as cellular proliferation and apoptosis.PMID:38178680 | DOI:10.2174/0113862073243966231030093213 (Source: Combinatorial Chemistry and High Throughput Screening)
Source: Combinatorial Chemistry and High Throughput Screening - January 5, 2024 Category: Chemistry Authors: Siming Tao Chunyan Liao Yide Wang Dan Xu Zheng Li Fengsen Li Source Type: research

Acupuncture Combined with Bushen-Jianpi Decoction Ameliorates the Ovarian Function of Diminished Ovarian Reserve Rats by Regulating Phosphoinositide 3-Kinase/AKT Signaling
CONCLUSION: Combining acupuncture with BJD can enhance ovarian function in DOR rats. The regulation of sex hormone levels and immune function in rats may be attributed to the adjustment of the mRNA and proteins levels of PI3K, AKT, and caspase-3 in the PI3K/AKT signaling pathway, which leads to an improvement in the immune function of DOR rats.PMID:38178681 | DOI:10.2174/0113862073264971231113061204 (Source: Combinatorial Chemistry and High Throughput Screening)
Source: Combinatorial Chemistry and High Throughput Screening - January 5, 2024 Category: Chemistry Authors: Jianting Lao Panwei Hu Jia Li Jiahui Li Xiaole Zhang Hong Yang Cong Qi Source Type: research

A Network Pharmacology-based Study on the Anti-aging Properties of Traditional Chinese Medicine Sisheng Bulao Elixir
CONCLUSION: This study offers novel insights into SBE's anti-aging attributes, providing evidence of its molecular mechanisms. It enhances our understanding of traditional remedies in anti-aging research.PMID:38178682 | DOI:10.2174/0113862073276253231114063813 (Source: Combinatorial Chemistry and High Throughput Screening)
Source: Combinatorial Chemistry and High Throughput Screening - January 5, 2024 Category: Chemistry Authors: Cencan Xing Zehua Zeng Yubang Shan Wenhuan Guo Roshan Shah Luna Wang Yan Wang Hongwu Du Source Type: research

Transcriptome Sequencing of Gingival Tissues from Impacted Third Molars Patients Reveals the Alterations of Gene Expression
CONCLUSION: This first transcriptome analysis of gingival tissues from patients with surgical removal of impacted third molars provides new insights into postoperative genetic changes. The results may establish a basis for future research on minimizing the incidence of complications after flap-treated third molars.PMID:38178683 | DOI:10.2174/0113862073256803231114095626 (Source: Combinatorial Chemistry and High Throughput Screening)
Source: Combinatorial Chemistry and High Throughput Screening - January 5, 2024 Category: Chemistry Authors: Haolin Zhou Nanqing Fu Yuan Tian Nini Zhang Qin Fan Fengjiao Zeng Yueyue Wang Guohui Bai Bin Chen Source Type: research

Evaluation of the Mechanism of Yishan Formula in Treating Breast Cancer Based on Network Pharmacology and Experimental Verification
CONCLUSION: This study showed that resistance to breast cancer may be achieved by the synergy of multiple active components, target genes, and signal pathways, which can provide new avenues for breast cancer-targeted therapy.PMID:38178684 | DOI:10.2174/0113862073266004231105164321 (Source: Combinatorial Chemistry and High Throughput Screening)
Source: Combinatorial Chemistry and High Throughput Screening - January 5, 2024 Category: Chemistry Authors: Xiaoyue Lin Wencheng Chi Xue Geng Qinghui Jiang Baozhu Ma Bowen Dai Yutong Sui Jiakang Jiang Source Type: research