Combinatorial Chemistry and High Throughput Screening This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Molecular Dynamics of a N-Cyclohexyl-1,2,4-Oxadiazole Derivative as a Reversible Cruzain Inhibitor in Trypanosoma cruzi
CONCLUSION: Finally, the findings indicate that the investigated molecule 2b can interfere enzymatic activity of cruzain, indicating that it might be a promising antichagasic drug.PMID:37957896 | DOI:10.2174/0113862073268297231025110913 (Source: Combinatorial Chemistry and High Throughput Screening)
Source: Combinatorial Chemistry and High Throughput Screening - November 14, 2023 Category: Chemistry Authors: Yasmim Mendes Rocha Gabriel Ac ácio de Moura Jo ão Pedro Viana Rodrigues Cristian Vicson Gomes Pinheiro Ronaldo Nascimento de Oliveira Marcia Machado Marinho Roberto Nicolete Source Type: research

Patterns of Gene Expression Profiles Associated with Colorectal Cancer in Colorectal Mucosa by Using Machine Learning Methods
CONCLUSION: This study summarized four sets of quantitative classification rules based on the DT algorithm, providing clues for understanding the microenvironmental changes caused by CRC. According to the rules, the effect of CRC on normal mucosa can be determined.PMID:37957897 | DOI:10.2174/0113862073266300231026103844 (Source: Combinatorial Chemistry and High Throughput Screening)
Source: Combinatorial Chemistry and High Throughput Screening - November 14, 2023 Category: Chemistry Authors: Jing Xin Ren Lei Chen Wei Guo Kai Yan Feng Tao Huang Yu-Dong Cai Source Type: research

Identification of Key Prognostic Alternative Splicing Events of Costimulatory Molecule-Related Genes in Colon Cancer
CONCLUSION: The identified differentially expressed alternative splicing events of costimulatory molecule-related genes may be used to predict patient prognosis and immunotherapy responses in colon cancer.PMID:37957898 | DOI:10.2174/0113862073249972231026060301 (Source: Combinatorial Chemistry and High Throughput Screening)
Source: Combinatorial Chemistry and High Throughput Screening - November 14, 2023 Category: Chemistry Authors: Hao Ding Huiwen Shi Weifeng Chen Zhisheng Liu Zhi Yang Xiaochuan Li Zhichao Qiu Hongqing Zhuo Source Type: research

Antiviral Activity of Natural Herbs and their Isolated Bioactive Compounds: A Review
Comb Chem High Throughput Screen. 2023 Nov 10. doi: 10.2174/0113862073267048231027070537. Online ahead of print.ABSTRACTViruses are the cause of many human pathogenesis-related conditions. A serious hazard to public health has been created because of the increase in worldwide travel, fast urbanization, and infectious epidemics. At the same time, no preventative vaccines or antiviral treatments are currently available. Resources for developing new antiviral medications can be found in enhanced natural products and herbal medicines. These natural substances have aided the research on developing preventive vaccines and antivi...
Source: Combinatorial Chemistry and High Throughput Screening - November 14, 2023 Category: Chemistry Authors: Sonia Singh Yogesh Murti Bhupesh Semwal Source Type: research

Integrating Network Pharmacology and In vivo Experimental Validation to Reveal the Mechanism of FuZheng YiLiu Formula on Estrogen Receptor Positive Breast Cancer
CONCLUSION: In this study, the potential active ingredients, potential core targets, key biological pathways, and signaling pathways involved in the treatment of breast cancer with FZYL were identified, providing a theoretical basis for further anti ER+ breast cancer research.PMID:37957900 | DOI:10.2174/0113862073255044231027061742 (Source: Combinatorial Chemistry and High Throughput Screening)
Source: Combinatorial Chemistry and High Throughput Screening - November 14, 2023 Category: Chemistry Authors: Yuan Xu Ying-Xuan Zhang Hong-Yu Chen Li-Sheng Chang Xiao-Jun Gou Wen-Li Chen Source Type: research