Beyond the G protein α subunit: investigating the functional impact of other components of the Gαi3 heterotrimers
Specific interactions between G protein-coupled receptors (GPCRs) and G proteins play a key role in mediating signaling events. While there is little doubt regarding receptor preference for G α subunits, the pr... (Source: Cell Communication and Signaling)
Source: Cell Communication and Signaling - October 10, 2023 Category: Molecular Biology Authors: Beata Rysiewicz, Ewa B łasiak, Paweł Mystek, Marta Dziedzicka-Wasylewska and Agnieszka Polit Tags: Research Source Type: research
Carbon dioxide and MAPK signalling: towards therapy for inflammation
Inflammation, although necessary to fight infections, becomes a threat when it exceeds the capability of the immune system to control it. In addition, inflammation is a cause and/or symptom of many different d... (Source: Cell Communication and Signaling)
Source: Cell Communication and Signaling - October 10, 2023 Category: Molecular Biology Authors: Hanna Ga łgańska, Wieslawa Jarmuszkiewicz and Łukasz Gałgański Tags: Review Source Type: research
Allergen-induced CD11c + dendritic cell pyroptosis aggravates allergic rhinitis
Pyroptosis is crucial for controlling various immune cells. However, the role of allergen-induced CD11c + dendritic cell (DC) pyroptosis in allergic rhinitis (AR) remains unclear. (Source: Cell Communication and Signaling)
Source: Cell Communication and Signaling - October 10, 2023 Category: Molecular Biology Authors: Yue-Long Qiao, Ming-Wan Zhu, Shan Xu, Wo-Er Jiao, Hai-Feng Ni, Ze-Zhang Tao and Shi-Ming Chen Tags: Research Source Type: research
Abnormal adipogenic signaling in the bone marrow mesenchymal stem cells contributes to supportive microenvironment for leukemia development
Acute myeloid leukemia (AML) is an aggressive hematological malignancy, associated with unfavorable patient outcome, primarily due to disease relapse. Mesenchymal stem cells (MSCs) residing in the bone marrow ... (Source: Cell Communication and Signaling)
Source: Cell Communication and Signaling - October 10, 2023 Category: Molecular Biology Authors: Rawan Sabbah, Sahar Saadi, Tal Shahar-Gabay, Shiran Gerassy, Shlomit Yehudai-Resheff and Tsila Zuckerman Tags: Research Source Type: research
The mechanism of oleic acid inhibiting platelet activation stimulated by collagen
Abnormal platelet activation is a key factor in the occurrence and development of thrombotic diseases. However, the physiological mechanisms that underlie platelet homeostasis remain unclear. Oleic acid, one o... (Source: Cell Communication and Signaling)
Source: Cell Communication and Signaling - October 10, 2023 Category: Molecular Biology Authors: Xianghui Zhou, Xin Zhou, Ruirui Zhu, Zhangyin Ming, Zhipeng Cheng and Yu Hu Tags: Research Source Type: research
