Cell-cell communication characteristics in breast cancer metastasis
Breast cancer, a highly fatal disease due to its tendency to metastasize, is the most prevalent form of malignant tumors among women worldwide. Numerous studies indicate that breast cancer exhibits a unique pr... (Source: Cell Communication and Signaling)
Source: Cell Communication and Signaling - January 19, 2024 Category: Molecular Biology Authors: Jingtong Xu, Fangyan Gao, Weici Liu and Xiaoxiang Guan Tags: Review Source Type: research
New immunotherapy approaches for colorectal cancer: focusing on CAR-T cell, BiTE, and oncolytic viruses
Colorectal cancer is one of the most common causes of mortality worldwide. There are several potential risk factors responsible for the initiation and progression of colorectal cancer, including age, family hi... (Source: Cell Communication and Signaling)
Source: Cell Communication and Signaling - January 19, 2024 Category: Molecular Biology Authors: Amin Kamrani, Hadi Nasiri, Ali Hassanzadeh, Javad Ahmadian Heris, Reza Mohammadinasab, Shahram Sadeghvand, Mohammadreza Sadeghi, Zahra Valedkarimi, Ramin Hosseinzadeh, Navid Shomali and Morteza Akbari Tags: Review Source Type: research
Extracellular lipidosomes containing lipid droplets and mitochondria are released during melanoma cell division
The incidence of melanoma is increasing worldwide. Since metastatic melanoma is highly aggressive, it is important to decipher all the biological aspects of melanoma cells. In this context, we have previously ... (Source: Cell Communication and Signaling)
Source: Cell Communication and Signaling - January 19, 2024 Category: Molecular Biology Authors: Jana Karbanov á, Ilker A. Deniz, Michaela Wilsch-Bräuninger, Rita Alexandra de Sousa Couto, Christine A. Fargeas, Mark F. Santos, Aurelio Lorico and Denis Corbeil Tags: Research Source Type: research
Adipo-oncology: adipocyte-derived factors govern engraftment, survival, and progression of metastatic cancers
Conventional therapies for metastatic cancers have limited efficacy. Recently, cancer therapies targeting noncancerous cells in tumor microenvironments have shown improved clinical outcomes in patients. Howeve... (Source: Cell Communication and Signaling)
Source: Cell Communication and Signaling - January 18, 2024 Category: Molecular Biology Authors: Shinya Sato Tags: Review Source Type: research
Mitochondria-derived methylmalonic acid aggravates ischemia –reperfusion injury by activating reactive oxygen species-dependent ferroptosis
In this study, we in... (Source: Cell Communication and Signaling)
Source: Cell Communication and Signaling - January 18, 2024 Category: Molecular Biology Authors: Junchen Guo, Shanjie Wang, Xin Wan, Xiaoxuan Liu, Zeng Wang, Chenchen Liang, Zhenming Zhang, Ye Wang, Miao Yan, Pengyan Wu, Shaohong Fang and Bo Yu Tags: Research Source Type: research
Egr-1 is a key regulator of the blood-brain barrier damage induced by meningitic Escherichia coli
Bacterial meningitis remains a leading cause of infection-related mortality worldwide. Although Escherichia coli (E. coli) is the most common etiology of neonatal meningitis, the underlying mechanisms governing b... (Source: Cell Communication and Signaling)
Source: Cell Communication and Signaling - January 17, 2024 Category: Molecular Biology Authors: Ruicheng Yang, Xinyi Wang, Hulin Liu, Jiaqi Chen, Chen Tan, Huanchun Chen and Xiangru Wang Tags: Research Source Type: research
Recent advances in the potential role of RNA N4-acetylcytidine in cancer progression
N4-acetylcytidine (ac4C) is a highly conserved chemical modification widely found in eukaryotic and prokaryotic RNA, such as tRNA, rRNA, and mRNA. This modification is significantly associated with various human ... (Source: Cell Communication and Signaling)
Source: Cell Communication and Signaling - January 17, 2024 Category: Molecular Biology Authors: Shujun Zhang, Yafeng Liu, Xiao Ma, Xiaohui Gao, Yi Ru, Xinjun Hu and Xinyu Gu Tags: Review Source Type: research
Neutrophil extracellular traps mediated by platelet microvesicles promote thrombosis and brain injury in acute ischemic stroke
Neutrophil extracellular traps (NETs) have been implicated in thrombotic diseases. There is no definitive explanation for how NETs form during acute ischemic strokes (AIS). The purpose of our study was to inve... (Source: Cell Communication and Signaling)
Source: Cell Communication and Signaling - January 17, 2024 Category: Molecular Biology Authors: Xin Gao, Xinyi Zhao, Jiacheng Li, Chang Liu, Wenqiang Li, Junjie Zhao, Zhixi Li, Nan Wang, Fang Wang, Jiawei Dong, Xiuwei Yan, Jiheng Zhang, Xueyan Hu, Jiaqi Jin, Ge Mang, Ruishuang Ma & hellip; Tags: Research Source Type: research
Cigarette tar accelerates atherosclerosis progression via RIPK3-dependent necroptosis mediated by endoplasmic reticulum stress in vascular smooth muscle cells
Tar is the main toxic of cigarettes, and its effect on atherosclerosis progression and the underlying mechanisms remain largely unknown. Vascular smooth muscle cells (VSMCs) play a key role in atherogenesis an... (Source: Cell Communication and Signaling)
Source: Cell Communication and Signaling - January 16, 2024 Category: Molecular Biology Authors: Xiaoxuan Bai, Ying Wang, Xing Luo, Xiaoyi Bao, Xiuzhu Weng, Yuwu Chen, Shan Zhang, Ying Lv, Xinyu Dai, Ming Zeng, Dan Yang, Sining Hu, Ji Li, Yong Ji, Haibo Jia and Bo Yu Tags: Research Source Type: research
Correction: Bacillus cereus extracellular vesicles act as shuttles for biologically active multicomponent enterotoxins
(Source: Cell Communication and Signaling)
Source: Cell Communication and Signaling - January 15, 2024 Category: Molecular Biology Authors: Tanja Buchacher, Astrid Digruber, Markus Kranzler, Giorgia Del Favero and Monika Ehling-Schulz Tags: Correction Source Type: research
SARS-CoV-2 S protein activates NLRP3 inflammasome and deregulates coagulation factors in endothelial and immune cells
Hyperinflammation, hypercoagulation and endothelial injury are major findings in acute and post-COVID-19. The SARS-CoV-2 S protein has been detected as an isolated element in human tissues reservoirs and is th... (Source: Cell Communication and Signaling)
Source: Cell Communication and Signaling - January 15, 2024 Category: Molecular Biology Authors: Alicia Villacampa, Enrique Alfaro, Cristina Morales, Elena D íaz-García, Cristina López-Fernández, José Luis Bartha, Francisco López-Sánchez, Óscar Lorenzo, Salvador Moncada, Carlos F. Sánchez-Ferrer, Francisco García-Río, Carolina Cubillos-Zap Tags: Research Source Type: research
Alcohol and e-cigarette damage alveolar-epithelial barrier by activation of P2X7r and provoke brain endothelial injury via extracellular vesicles
Use of nicotine containing products like electronic cigarettes (e-Cig) and alcohol are associated with mitochondrial membrane depolarization, resulting in the extracellular release of ATP, and mitochondrial DN... (Source: Cell Communication and Signaling)
Source: Cell Communication and Signaling - January 15, 2024 Category: Molecular Biology Authors: Naveen Mekala, Jayshil Trivedi, Priyanka Bhoj, Namdev Togre, Slava Rom, Uma Sriram and Yuri Persidsky Tags: Research Source Type: research
Pyroptosis: a double-edged sword in lung cancer and other respiratory diseases
Pyroptosis is an active cell death process mediated by gasdermin family proteins including Gasdermin A (GSDMA), Gasdermin B (GSDMB), Gasdermin C (GSDMC), Gasdermin D (GSDMD), Gasdermin E (GSDME, DFNA5), and DF... (Source: Cell Communication and Signaling)
Source: Cell Communication and Signaling - January 15, 2024 Category: Molecular Biology Authors: Xiao Liang, Ya Qin, Dan Wu, Qiong Wang and Hongshuai Wu Tags: Review Source Type: research
The involvement of α-synucleinopathy in the disruption of microglial homeostasis contributes to the pathogenesis of Parkinson’s disease
The intracellular deposition and intercellular transmission of α-synuclein (α-syn) are shared pathological characteristics among neurodegenerative disorders collectively known as α-synucleinopathies, including... (Source: Cell Communication and Signaling)
Source: Cell Communication and Signaling - January 12, 2024 Category: Molecular Biology Authors: Yongzhen Miao and Hongrui Meng Tags: Review Source Type: research
A slow-releasing donor of hydrogen sulfide inhibits neuronal cell death via anti-PANoptosis in rats with spinal cord ischemia ‒reperfusion injury
Spinal cord ischemia ‒reperfusion injury (SCIRI) can lead to paraplegia, which leads to permanent motor function loss. It is a disastrous complication of surgery and causes tremendous socioeconomic burden. Howe... (Source: Cell Communication and Signaling)
Source: Cell Communication and Signaling - January 12, 2024 Category: Molecular Biology Authors: Lei Xie, Hang Wu, Qiuping He, Weipeng Shi, Jing Zhang, Xiao Xiao and Tengbo Yu Tags: Research Source Type: research
