Immunophenotype profile by flow cytometry reveals different subtypes of extracellular vesicles in porcine seminal plasma
This study evaluated the immunophenotypic profile by high-sensitivity flow cytometry of eight sEV subpop... (Source: Cell Communication and Signaling)
Source: Cell Communication and Signaling - January 23, 2024 Category: Molecular Biology Authors: Isabel Barranco, Alberto Alvarez-Barrientos, Ana Parra, Pablo Mart ínez-Díaz, Xiomara Lucas and Jordi Roca Tags: Research Source Type: research

Correction: SARS-CoV-2  S protein activates NLRP3 inflammasome and deregulates coagulation factors in endothelial and immune cells
(Source: Cell Communication and Signaling)
Source: Cell Communication and Signaling - January 23, 2024 Category: Molecular Biology Authors: Alicia Villacampa, Enrique Alfaro, Cristina Morales, Elena D íaz-García, Cristina López-Fernández, José Luis Bartha, Francisco López-Sánchez, Óscar Lorenzo, Salvador Moncada, Carlos F. Sánchez-Ferrer, Francisco García-Río, Carolina Cubillos-Zap Tags: Correction Source Type: research

Paxillin participates in the sphingosylphosphorylcholine-induced abnormal contraction of vascular smooth muscle by regulating Rho-kinase activation
The Ca2+-independent contraction of vascular smooth muscle is a leading cause of cardiovascular and cerebrovascular spasms. In the previous study, we demonstrated the involvement of Src family protein tyrosine ki... (Source: Cell Communication and Signaling)
Source: Cell Communication and Signaling - January 22, 2024 Category: Molecular Biology Authors: Ying Zhang, Nan Li and Sei Kobayashi Tags: Research Source Type: research

The role of exhausted natural killer cells in the immunopathogenesis and treatment of leukemia
The immune responses to cancer cells involve both innate and acquired immune cells. In the meantime, the most attention has been drawn to the adaptive immune cells, especially T cells, while, it is now well kn... (Source: Cell Communication and Signaling)
Source: Cell Communication and Signaling - January 22, 2024 Category: Molecular Biology Authors: Asal Barshidi, Keivan Ardeshiri, Farbod Ebrahimi, Fatemeh Alian, Ali Akbar Shekarchi, Mohammad Hojjat-Farsangi and Farhad Jadidi-Niaragh Tags: Review Source Type: research

A positive feedback between PDIA3P1 and OCT4 promotes the cancer stem cell properties of esophageal squamous cell carcinoma
Increasing evidence has indicated that long non-coding RNAs (lncRNAs) have been proven to regulate esophageal cancer progression. The lncRNA protein disulfide isomerase family A member 3 pseudogene 1 (PDIA3P1)... (Source: Cell Communication and Signaling)
Source: Cell Communication and Signaling - January 22, 2024 Category: Molecular Biology Authors: Tao Huang, Qi You, Dengjun Huang, Yan Zhang, Zhijie He, Xuguang Shen, Fei Li, Qiang Shen, Ifeanyi Christian Onyebuchi, Chengwei Wu, Feng Liu and Shaojin Zhu Tags: Research Source Type: research

Faecalibacterium prausnitzii as a potential Antiatherosclerotic microbe
This study aimed to identify... (Source: Cell Communication and Signaling)
Source: Cell Communication and Signaling - January 19, 2024 Category: Molecular Biology Authors: Hai-Tao Yang, Zhi-hui Jiang, Yi Yang, Ting-Ting Wu, Ying-Ying Zheng, Yi-Tong Ma and Xiang Xie Tags: Research Source Type: research

Cell-cell communication characteristics in breast cancer metastasis
Breast cancer, a highly fatal disease due to its tendency to metastasize, is the most prevalent form of malignant tumors among women worldwide. Numerous studies indicate that breast cancer exhibits a unique pr... (Source: Cell Communication and Signaling)
Source: Cell Communication and Signaling - January 19, 2024 Category: Molecular Biology Authors: Jingtong Xu, Fangyan Gao, Weici Liu and Xiaoxiang Guan Tags: Review Source Type: research

New immunotherapy approaches for colorectal cancer: focusing on CAR-T cell, BiTE, and oncolytic viruses
Colorectal cancer is one of the most common causes of mortality worldwide. There are several potential risk factors responsible for the initiation and progression of colorectal cancer, including age, family hi... (Source: Cell Communication and Signaling)
Source: Cell Communication and Signaling - January 19, 2024 Category: Molecular Biology Authors: Amin Kamrani, Hadi Nasiri, Ali Hassanzadeh, Javad Ahmadian Heris, Reza Mohammadinasab, Shahram Sadeghvand, Mohammadreza Sadeghi, Zahra Valedkarimi, Ramin Hosseinzadeh, Navid Shomali and Morteza Akbari Tags: Review Source Type: research

Extracellular lipidosomes containing lipid droplets and mitochondria are released during melanoma cell division
The incidence of melanoma is increasing worldwide. Since metastatic melanoma is highly aggressive, it is important to decipher all the biological aspects of melanoma cells. In this context, we have previously ... (Source: Cell Communication and Signaling)
Source: Cell Communication and Signaling - January 19, 2024 Category: Molecular Biology Authors: Jana Karbanov á, Ilker A. Deniz, Michaela Wilsch-Bräuninger, Rita Alexandra de Sousa Couto, Christine A. Fargeas, Mark F. Santos, Aurelio Lorico and Denis Corbeil Tags: Research Source Type: research

Adipo-oncology: adipocyte-derived factors govern engraftment, survival, and progression of metastatic cancers
Conventional therapies for metastatic cancers have limited efficacy. Recently, cancer therapies targeting noncancerous cells in tumor microenvironments have shown improved clinical outcomes in patients. Howeve... (Source: Cell Communication and Signaling)
Source: Cell Communication and Signaling - January 18, 2024 Category: Molecular Biology Authors: Shinya Sato Tags: Review Source Type: research

Mitochondria-derived methylmalonic acid aggravates ischemia –reperfusion injury by activating reactive oxygen species-dependent ferroptosis
In this study, we in... (Source: Cell Communication and Signaling)
Source: Cell Communication and Signaling - January 18, 2024 Category: Molecular Biology Authors: Junchen Guo, Shanjie Wang, Xin Wan, Xiaoxuan Liu, Zeng Wang, Chenchen Liang, Zhenming Zhang, Ye Wang, Miao Yan, Pengyan Wu, Shaohong Fang and Bo Yu Tags: Research Source Type: research

Egr-1 is a key regulator of the blood-brain barrier damage induced by meningitic Escherichia coli
Bacterial meningitis remains a leading cause of infection-related mortality worldwide. Although Escherichia coli (E. coli) is the most common etiology of neonatal meningitis, the underlying mechanisms governing b... (Source: Cell Communication and Signaling)
Source: Cell Communication and Signaling - January 17, 2024 Category: Molecular Biology Authors: Ruicheng Yang, Xinyi Wang, Hulin Liu, Jiaqi Chen, Chen Tan, Huanchun Chen and Xiangru Wang Tags: Research Source Type: research

Recent advances in the potential role of RNA N4-acetylcytidine in cancer progression
N4-acetylcytidine (ac4C) is a highly conserved chemical modification widely found in eukaryotic and prokaryotic RNA, such as tRNA, rRNA, and mRNA. This modification is significantly associated with various human ... (Source: Cell Communication and Signaling)
Source: Cell Communication and Signaling - January 17, 2024 Category: Molecular Biology Authors: Shujun Zhang, Yafeng Liu, Xiao Ma, Xiaohui Gao, Yi Ru, Xinjun Hu and Xinyu Gu Tags: Review Source Type: research

Neutrophil extracellular traps mediated by platelet microvesicles promote thrombosis and brain injury in acute ischemic stroke
Neutrophil extracellular traps (NETs) have been implicated in thrombotic diseases. There is no definitive explanation for how NETs form during acute ischemic strokes (AIS). The purpose of our study was to inve... (Source: Cell Communication and Signaling)
Source: Cell Communication and Signaling - January 17, 2024 Category: Molecular Biology Authors: Xin Gao, Xinyi Zhao, Jiacheng Li, Chang Liu, Wenqiang Li, Junjie Zhao, Zhixi Li, Nan Wang, Fang Wang, Jiawei Dong, Xiuwei Yan, Jiheng Zhang, Xueyan Hu, Jiaqi Jin, Ge Mang, Ruishuang Ma & hellip; Tags: Research Source Type: research

Cigarette tar accelerates atherosclerosis progression via RIPK3-dependent necroptosis mediated by endoplasmic reticulum stress in vascular smooth muscle cells
Tar is the main toxic of cigarettes, and its effect on atherosclerosis progression and the underlying mechanisms remain largely unknown. Vascular smooth muscle cells (VSMCs) play a key role in atherogenesis an... (Source: Cell Communication and Signaling)
Source: Cell Communication and Signaling - January 16, 2024 Category: Molecular Biology Authors: Xiaoxuan Bai, Ying Wang, Xing Luo, Xiaoyi Bao, Xiuzhu Weng, Yuwu Chen, Shan Zhang, Ying Lv, Xinyu Dai, Ming Zeng, Dan Yang, Sining Hu, Ji Li, Yong Ji, Haibo Jia and Bo Yu Tags: Research Source Type: research