Populational Perceptions Regarding Decision to Visit the Emergency Room with Chest Pain During COVID-19
ConclusionsThe risk of contracting COVID-19 while presenting to the ED for a life-threatening cardiovascular symptom is overestimated and is strongly affected by social factors. (Source: Cardiology and Therapy)
Source: Cardiology and Therapy - March 22, 2022 Category: Cardiology Source Type: research
Safety of Transcatheter Aortic Valve Replacement in Patients with Aortic Aneurysm: A Propensity-Matched Analysis
ConclusionsData from a large nationwide database demonstrated that patients with AA undergoing TAVR are associated with similar in-hospital outcomes compared with patients without AA. (Source: Cardiology and Therapy)
Source: Cardiology and Therapy - March 6, 2022 Category: Cardiology Source Type: research
Imaging Findings in Pediatric COVID-19: A Review of Current Literature
We describe the expected clinical course of these patients and note the lack of long-term follow-up data and the concerning prevalence of continued abnormal findings on follow-up imaging. With this paucity of long-term cardiac data, we recommend consideration of advanced imaging for pediatric patients with cardiac symptoms and/or elevation of cardiac serum biomarkers. (Source: Cardiology and Therapy)
Source: Cardiology and Therapy - March 2, 2022 Category: Cardiology Source Type: research
Prevention of Cardiovascular Burden in COVID-19 Patients Suffering from Familial Hypercholesterolemia: A Global Challenge
AbstractA recent meta-analysis of over 20,000 individuals showed that hospitalized COVID-19 patients with acute myocardial injury had more than fourfold higher mortality than those without such injury. Since the COVID-19 pandemic exacerbates already existing health inequalities, there is an urgent need to create measures to protect the most vulnerable patient groups, including those with a pre-existing increased risk of atherosclerotic cardiovascular disease (ASCVD). A typical example is familial hypercholesterolemia (FH), a common genetic disease affecting over 30 million individuals worldwide. If left untreated or undert...
Source: Cardiology and Therapy - March 1, 2022 Category: Cardiology Source Type: research
Original Research: Long-Term Prognosis After ST-Elevation Myocardial Infarction in Patients with a Prior Cancer Diagnosis
ConclusionsPatients with a prior cancer diagnosis admitted with STEMI have a poor survival rate. However, when the STEMI is optimally treated with primary PCI and medication, cardiac mortality is low, and prognosis is mainly determined by factors related to cancer stage. (Source: Cardiology and Therapy)
Source: Cardiology and Therapy - March 1, 2022 Category: Cardiology Source Type: research
Usefulness of Postnatal Echocardiograms in Patients with Omphaloceles Who Previously Had a Normal Fetal Echocardiogram
ConclusionCritical CHD was not missed on any patient with an omphalocele who had a normal fetal echocardiogram. All other patients with omphaloceles who had CHD diagnosed postnatally had an abnormal clinical finding on postnatal evaluation. The routine performance of a postnatal TTE in patients with an omphalocele who had a normal fetal echocardiogram may not be needed in those with a normal clinical workup. Further studies evaluating echocardiographic imaging recommendations are needed to maximize care and optimize resource allocation in this complex patient population. (Source: Cardiology and Therapy)
Source: Cardiology and Therapy - March 1, 2022 Category: Cardiology Source Type: research
Cardiovascular Complications of SARS-CoV-2 Vaccines: An Overview
AbstractSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of the deadly disease known as coronavirus disease 2019 (COVID-19) that has reached pandemic proportions. Currently, there is no definitive treatment for COVID-19, although many vaccines have been developed. The World Health Organization has approved the safety and efficacy of the AstraZeneca/Oxford, Johnson and Johnson/Janssen (JnJ), Moderna, Pfizer/BioNTech, Sinopharm, and Sinovac vaccines so far. The approved formulations of AstraZeneca, JnJ, and Gam-COVID-vac (Sputnik V) contain DNA delivered within non-replicating recombinant adenovirus ...
Source: Cardiology and Therapy - March 1, 2022 Category: Cardiology Source Type: research
Caring for a Child with Hypoplastic Left Heart Syndrome: Parent and Medical Perspective
This article, co-authored by parents of a child with hypoplastic left heart syndrome (HLHS) and his pediatric cardiology care team, discusses the parents ’ experience of having a child with HLHS from diagnosis through living day-to-day with the heart condition as well as future directions. (Source: Cardiology and Therapy)
Source: Cardiology and Therapy - March 1, 2022 Category: Cardiology Source Type: research
Treatment Changes, Healthcare Resource Utilization, and Costs Among Patients with Symptomatic Obstructive Hypertrophic Cardiomyopathy: A Claims Database Study
ConclusionsPatients experienced high rates of treatment changes, and the economic burden associated with symptomatic obstructive HCM increased as therapy escalated. More effective therapies are needed to stabilize or decrease the economic burden of obstructive HCM. (Source: Cardiology and Therapy)
Source: Cardiology and Therapy - March 1, 2022 Category: Cardiology Source Type: research
Evaluation of Effectiveness and Tolerability of Fondaparinux in the Management of Symptomatic Acute Coronary Syndrome: A Real-World Evidence-Based Study on an Indian Population
ConclusionsIn the real world, fondaparinux was found to be effective and tolerable when used to manage symptomatic ACS patients regardless of revascularization procedure with no incidence of stent thrombosis, and minimal recurrent ACS and insignificant increase in bleeding events. (Source: Cardiology and Therapy)
Source: Cardiology and Therapy - February 9, 2022 Category: Cardiology Source Type: research
Expert Recommendations on the Usage of Non-vitamin K Antagonist Oral Anticoagulants (NOACs) from India: Current Perspective and Future Direction
AbstractNon-vitamin K antagonist oral anticoagulants (NOACs) are a new class of anticoagulant drugs used in the prevention and treatment of venous thromboembolism (VTE) and atrial fibrillation (AF). Anticoagulation requires the integration of the correct type and dose of oral anticoagulants based on patient characteristic, and therefore therapy needs to be individualized for each patient. Growing scientific evidence from studies on NOACs has led to a better understanding of their benefits and safety. A large amount of available data creates a necessity for an adaptable practical document for the usage of NOACs in India. Th...
Source: Cardiology and Therapy - February 8, 2022 Category: Cardiology Source Type: research
Hospitalization Rates in Patients with Heart Failure and Reduced Ejection Fraction Initiating Sacubitril/Valsartan or Angiotensin-Converting Enzyme Inhibitors/Angiotensin Receptor Blockers: A Retrospective Cohort Study
ConclusionsIn real-world clinical practice, RAASi-na ïve patients with HFrEF initiating SAC/VAL were less likely to be hospitalized than those initiating ACEi/ARB, suggesting a potential for a reduced clinical and economic burden in these patients. (Source: Cardiology and Therapy)
Source: Cardiology and Therapy - January 29, 2022 Category: Cardiology Source Type: research
Pulmonary Hypertension in the Population with Down Syndrome
This article will additionally review current known and probable risk factors for developing PH, review pathophysiologic mechanisms of disease in the population with DS, and evaluate current screening and management recommendations while suggesting areas for additional or ongoing clinical, translational, and basic science research. (Source: Cardiology and Therapy)
Source: Cardiology and Therapy - January 16, 2022 Category: Cardiology Source Type: research
Coronary Microvascular Disease
AbstractCoronary microvascular disease or dysfunction (CMVD) has been associated with adverse cardiovascular outcomes. Despite a growing prevalence, guidelines on definitive treatment are lacking. Proposed mechanisms of endothelial dysfunction and resultant inflammation have been demonstrated as the underlying cause. Imaging modalities such as echocardiography, cardiac MRI, PET, and in some instances CT, have been shown to be useful in diagnosing CMVD mainly through assessment of coronary blood flow. Invasive measurements through thermodilution and pressure sensor-guided Doppler microcatheters have also been utilized. Trea...
Source: Cardiology and Therapy - January 7, 2022 Category: Cardiology Source Type: research
Effectiveness and Tolerability of Trimetazidine 80 Mg Once Daily in Patients with Stable Angina Uncontrolled with Bisoprolol-Based Therapy: The Modus Vivendi Observational Study
ConclusionThe study findings support the addition of TMZ 80 OD to bisoprolol with or without other antianginal therapies for patients with persistent angina.Trial RegistrationThis study was retrospectively registered under the number ISRCTN29992579. (Source: Cardiology and Therapy)
Source: Cardiology and Therapy - December 27, 2021 Category: Cardiology Source Type: research
