ARF6 promotes hepatocellular carcinoma proliferation through activating STAT3 signaling
In this study, we show that high expression ... (Source: Cancer Cell International)
Source: Cancer Cell International - September 16, 2023 Category: Cancer & Oncology Authors: Yabing Hu, Yongchu Huang, Xiaohang Xie, Longshan Li, Yong Zhang and Xiaochao Zhang Tags: Research Source Type: research
Targeting WEE1 kinase as a p53-independent therapeutic strategy in high-risk and relapsed acute lymphoblastic leukemia
Outcomes for patients with relapsed acute lymphoblastic leukemia (ALL) are poor and there is a need for novel therapies to improve outcomes. Targeted inhibition of WEE1 with small-molecule inhibitor adavoserti... (Source: Cancer Cell International)
Source: Cancer Cell International - September 15, 2023 Category: Cancer & Oncology Authors: Hayden L. Bell, Helen J. Blair, Mankaran Singh, Anthony V. Moorman, Olaf Heidenreich, Frederik W. van Delft, John Lunec and Julie A. E. Irving Tags: Research Source Type: research
Retraction Note: Targeting a novel LncRNA SNHG15/miR-451/c-Myc signaling cascade is effective to hamper the pathogenesis of breast cancer (BC) in vitro and in vivo
(Source: Cancer Cell International)
Source: Cancer Cell International - September 14, 2023 Category: Cancer & Oncology Authors: Jiang Du, Hong Zhong and Binlin Ma Tags: Retraction Note Source Type: research
Stimulators of immunogenic cell death for cancer therapy: focusing on natural compounds
A growing body of evidence indicates that the anticancer effect of the immune system can be activated by the immunogenic modulation of dying cancer cells. Cancer cell death, as a result of the activation of an... (Source: Cancer Cell International)
Source: Cancer Cell International - September 13, 2023 Category: Cancer & Oncology Authors: Mina Amiri, Ommoleila Molavi, Shahnaz Sabetkam, Sevda Jafari and Soheila Montazersaheb Tags: Review Source Type: research
EZH2-mediated epigenetic silencing of tumor-suppressive let-7c/miR-99a cluster by hepatitis B virus X antigen enhances hepatocellular carcinoma progression and metastasis
Hepatitis B virus (HBV)-encoded X antigen, HBx, assists in the development of hepatocellular carcinoma (HCC) through complex mechanisms. Our results provide new insights into the EZH2 epigenetic repression of ... (Source: Cancer Cell International)
Source: Cancer Cell International - September 9, 2023 Category: Cancer & Oncology Authors: Chen-Shiou Wu, Yi-Chung Chien, Chia ‐Jui Yen, Jia-Yan Wu, Li-Yuan Bai and Yung-Luen Yu Tags: Research Source Type: research
LncRNA SNHG1: role in tumorigenesis of multiple human cancers
Small nucleolar RNA host gene 1 (SNHG1) is an important member of the SNHG family. This family is composed of a group of host genes that can be processed into small nucleolar RNAs and play important biological... (Source: Cancer Cell International)
Source: Cancer Cell International - September 8, 2023 Category: Cancer & Oncology Authors: Huang Zeng, Shouang Zhou, Weiqiang Cai, Mingqiang Kang and Peipei Zhang Tags: Review Source Type: research
Combining old and new concepts in targeting telomerase for cancer therapy: transient, immediate, complete and combinatory attack (TICCA)
Telomerase can overcome replicative senescence by elongation of telomeres but is also a specific element in most cancer cells. It is expressed more vastly than any other tumor marker. Telomerase as a tumor tar... (Source: Cancer Cell International)
Source: Cancer Cell International - September 7, 2023 Category: Cancer & Oncology Authors: Jaber Haj Ali and Michael Walter Tags: Review Source Type: research
Identification and validation of a novel prognosis model based on m5C-related long non-coding RNAs in colorectal cancer
The prognosis of tumor patients can be assessed by measuring the levels of lncRNAs (long non-coding RNAs), which play a role in controlling the methylation of the RNA. Prognosis in individuals with colorectal ... (Source: Cancer Cell International)
Source: Cancer Cell International - September 5, 2023 Category: Cancer & Oncology Authors: Ziyang Di, Gaoran Xu, Zheyu Ding, Chengxin Li, Jialin Song, Guoquan Huang, Jinsen Zheng, Xinyao Zhang and Bin Xiong Tags: Research Source Type: research
Investigating genomic, proteomic, and post-transcriptional regulation profiles in colorectal cancer: a comparative study between primary tumors and associated metastases
This study investigates the possible molecular discrepancies between primary colorectal cancer (pCRC) and their respect... (Source: Cancer Cell International)
Source: Cancer Cell International - September 5, 2023 Category: Cancer & Oncology Authors: Hersh Ham-Karim, Ola Negm, Narmeen Ahmad and Mohammad Ilyas Tags: Research Source Type: research
Safety and efficacy of T-cell-redirecting bispecific antibodies for patients with multiple myeloma: a systematic review and meta-analysis
In recent years, several bispecific antibodies (BsAbs) have been introduced that revolutionized the treatment approach for patients with multiple myeloma (MM). In the present study, we sought for conducting a ... (Source: Cancer Cell International)
Source: Cancer Cell International - September 5, 2023 Category: Cancer & Oncology Authors: Maryam Noori, Niloufar Yazdanpanah and Nima Rezaei Tags: Review Source Type: research
LncRNA CYP4A22-AS1 promotes the progression of lung adenocarcinoma through the miR-205-5p/EREG and miR-34c-5p/BCL-2 axes
Lung adenocarcinoma (LUAD) exhibits a higher fatality rate among all cancer types worldwide, yet the precise mechanisms underlying its initiation and progression remain unknown. Mounting evidence suggests that... (Source: Cancer Cell International)
Source: Cancer Cell International - September 5, 2023 Category: Cancer & Oncology Authors: Liyao Dong, Lin Zhang, Xinyun Zhao, Hongling Zou, Sisi Lin, Xinping Zhu, Jili Cao, Chun Zhou, Zhihong Yu, Yongqiang Zhu, Kequn Chai, Mingqian Li and Qun Li Tags: Research Source Type: research
PTBP1 plays an important role in the development of gastric cancer
Polypyrimidine tract binding protein 1 (PTBP1) has been found to play an important role in the occurrence and development of various tumors. At present, the role of PTBP1 in gastric cancer (GC) is still unknow... (Source: Cancer Cell International)
Source: Cancer Cell International - September 5, 2023 Category: Cancer & Oncology Authors: Zewen Chu, Miao Zhu, Yuanyuan Luo, Yaqi Hu, Xinyi Feng, Haibo Wang, Masataka Sunagawa and Yanqing Liu Tags: Research Source Type: research
Progranulin promoted the proliferation, metastasis, and suppressed apoptosis via JAK2-STAT3/4 signaling pathway in papillary thyroid carcinoma
In this study, the expression, and functions of PGR... (Source: Cancer Cell International)
Source: Cancer Cell International - September 2, 2023 Category: Cancer & Oncology Authors: Yanxu Dong, Hao Tan, Lidong Wang and Zhen Liu Tags: Research Source Type: research
Angiogenesis modulated by CD93 and its natural ligands IGFBP7 and MMRN2: a new target to facilitate solid tumor therapy by vasculature normalization
The tumor vasculature was different from the normal vasculature in both function and morphology, which caused hypoxia in the tumor microenvironment (TME). Previous anti-angiogenesis therapy had led to a modest... (Source: Cancer Cell International)
Source: Cancer Cell International - September 2, 2023 Category: Cancer & Oncology Authors: Yang Li, Lei Fu, Baokang Wu, Xingqi Guo, Yu Shi, Chao Lv, Yang Yu, Yizhou Zhang, Zhiyun Liang, Chongli Zhong, Shukun Han, Feng Xu and Yu Tian Tags: Review Source Type: research
Icariin-Curcumol promotes docetaxel sensitivity in prostate cancer through modulation of the PI3K-Akt signaling pathway and the Warburg effect
This study aimed to determine whether E... (Source: Cancer Cell International)
Source: Cancer Cell International - September 2, 2023 Category: Cancer & Oncology Authors: Wenjing Xu, Jin Ding, Shida Kuang, Bonan Li, Tiansong Sun, Congxu Zhu, Juan Liu, Lemei Zhu, Yingqiu Li and Wen Sheng Tags: Research Source Type: research
