EZH2-mediated epigenetic silencing of tumor-suppressive let-7c/miR-99a cluster by hepatitis B virus X antigen enhances hepatocellular carcinoma progression and metastasis

Hepatitis B virus (HBV)-encoded X antigen, HBx, assists in the development of hepatocellular carcinoma (HCC) through complex mechanisms. Our results provide new insights into the EZH2 epigenetic repression of ...

Source: Cancer Cell International - September 9, 2023 Category: Cancer & Oncology Authors: Chen-Shiou Wu, Yi-Chung Chien, Chia ‐Jui Yen, Jia-Yan Wu, Li-Yuan Bai and Yung-Luen Yu Tags: Research Source Type: research