ANGPTL4 regulates ovarian cancer progression by activating the ERK1/2 pathway
Ovarian cancer (OC) has the highest mortality rate among all gynecological malignancies. A hypoxic microenvironment is a common feature of solid tumors, including ovarian cancer, and an important driving facto... (Source: Cancer Cell International)
Source: Cancer Cell International - February 4, 2024 Category: Cancer & Oncology Authors: Jiaqi Xu, Fei Wu, Yue Zhu, Tiantian Wu, Tianyue Cao, Wenxin Gao, Meng Liu, Weifeng Qian, Guannan Feng, Xiaoxue Xi and Shunyu Hou Tags: Research Source Type: research
Identification of four snoRNAs (SNORD16, SNORA73B, SCARNA4, and SNORD49B) as novel non-invasive biomarkers for diagnosis of breast cancer
This study aimed to clarify the differential expressions and potential diag... (Source: Cancer Cell International)
Source: Cancer Cell International - February 4, 2024 Category: Cancer & Oncology Authors: Xiao Li, Xuan Zhao, Li Xie, Xingguo Song and Xianrang Song Tags: Research Source Type: research
Anoikis-related signature predicts prognosis and characterizes immune landscape of ovarian cancer
Ovarian cancer (OV) is the most lethal gynecological malignancy worldwide, with high recurrence rates. Anoikis, a newly-acknowledged form of programmed cell death, plays an essential role in cancer progression... (Source: Cancer Cell International)
Source: Cancer Cell International - February 3, 2024 Category: Cancer & Oncology Authors: Jiani Yang, Yue Zhang, Shanshan Cheng, Yanna Xu, Meixuan Wu, Sijia Gu, Shilin Xu, Yongsong Wu, Chao Wang and Yu Wang Tags: Research Source Type: research
Robust machine −learning based prognostic index using cytotoxic T lymphocyte evasion genes highlights potential therapeutic targets in colorectal cancer
A minute fraction of patients stands to derive substantial benefits from immunotherapy, primarily attributable to immune evasion. Our objective was to formulate a predictive signature rooted in genes associate... (Source: Cancer Cell International)
Source: Cancer Cell International - January 31, 2024 Category: Cancer & Oncology Authors: Xu Wang, Shixin Chan, Jiajie Chen, Yuanmin Xu, Longfei Dai, Qijun Han, Zhenglin Wang, Xiaomin Zuo, Yang Yang, Hu Zhao, Ming Wang, Chen Wang, Zichen Li, Huabing Zhang and Wei Chen Tags: Research Source Type: research
EN1 promotes lung metastasis of salivary adenoid cystic carcinoma by regulating the PI3K-AKT pathway and epithelial-mesenchymal transition
Engrailed homeobox 1 (EN1) is a candidate oncogene that is epigenetically modified in salivary adenoid cystic carcinoma (SACC). We investigated the expression of EN1 in SACC tissues and cells, EN1 promoter methyl... (Source: Cancer Cell International)
Source: Cancer Cell International - January 30, 2024 Category: Cancer & Oncology Authors: Yajuan Cui, Ye Zhang, Yuping Liu, Zheng Zhou, Lijing Zhu and Chuan-Xiang Zhou Tags: Research Source Type: research
The m6A methyltransferase METTL3 drives thyroid cancer progression and lymph node metastasis by targeting LINC00894
Long noncoding RNAs (lncRNAs) are significant contributors to various human malignancies. The aberrant expression of lncRNA LINC00894 has been reported in various human malignancies. We aimed to illustrate the... (Source: Cancer Cell International)
Source: Cancer Cell International - January 30, 2024 Category: Cancer & Oncology Authors: Xiang Zhou, Lisha Chang, Qiaoqiao Liang, Rongjie Zhao, Yong Xiao, Zheng Xu and Leitao Yu Tags: Research Source Type: research
MicroRNA expression signature as a biomarker in the diagnosis of nodal T-cell lymphomas
The diagnosis of T-cell lymphomas is typically established through a multiparameter approach that combines clinical, morphologic, immunophenotypic, and genetic features, utilizing a variety of histopathologic ... (Source: Cancer Cell International)
Source: Cancer Cell International - January 30, 2024 Category: Cancer & Oncology Authors: Muhammad Sufyan Bin Masroni, Gracie Wee Ling Eng, Ah-Jung Jeon, Yuan Gao, He Cheng, Sai Mun Leong, Jit Kong Cheong, Susan Swee-Shan Hue and Soo Yong Tan Tags: Research Source Type: research
An estrogen-regulated long non-coding RNA NCALD promotes luminal breast cancer proliferation by activating GRHL2
Luminal breast cancer (BC) is a prevalent subtype associated with an increased risk of late disease recurrence and mortality. Long noncoding RNAs (lncRNAs) likely play significant roles in regulating tissue-sp... (Source: Cancer Cell International)
Source: Cancer Cell International - January 30, 2024 Category: Cancer & Oncology Authors: Yue Meng, Dianrong Zhou, Ying Luo, Jierong Chen and Hui Li Tags: Research Source Type: research
PD-1 inhibitor plus oncolytic vaccinia virus is a safe and effective treatment option for metastatic renal cell carcinoma
Although a combination of immune checkpoint inhibitors (ICIs) is recommended as the first line treatment option for metastatic renal cell carcinoma (mRCC), several immune-related adverse events (irAEs) occur, ... (Source: Cancer Cell International)
Source: Cancer Cell International - January 30, 2024 Category: Cancer & Oncology Authors: Jee Soo Park, Myung Eun Lee, Jongchan Kim, Keunhee Oh, Namhee Lee, Minsun Jung, Won Sik Jang and Won Sik Ham Tags: Research Source Type: research
Elucidating the role of Pyroptosis in papillary thyroid cancer: prognostic, immunological, and therapeutic perspectives
Pyroptosis, an inflammatory form of programmed cell death, has been implicated in the pathogenesis and progression of several cancers. However, the significance of pyroptosis-related genes (PRGs) in papillary ... (Source: Cancer Cell International)
Source: Cancer Cell International - January 29, 2024 Category: Cancer & Oncology Authors: Fang Li, Rui Du, Jiedong Kou, Jingting Li, Le Zhou, Daqi Zhang, Yantao Fu, Gianlorenzo Dionigi, Simona Bertoli, Hui Sun and Nan Liang Tags: Research Source Type: research
Fabrication of magnetic niosomal platform for delivery of resveratrol: potential anticancer activity against human pancreatic cancer Capan-1 cell
Recently, the presence of different nanoparticles (NPs) has developed targeting drug delivery in treatment of cancer cell. Targeted drug delivery systems using NPs have shown great promise in improving the eff... (Source: Cancer Cell International)
Source: Cancer Cell International - January 29, 2024 Category: Cancer & Oncology Authors: Akram Firouzi Amandi, Zahra Bahmanyar, Mehdi Dadashpour, Mehrnoosh Lak, Mohammad Natami, Yusuf D öğüş, Mahsa Alem and Omid Ali Adeli Tags: Research Source Type: research
The anti-tumor effects of AZD4547 on ovarian cancer cells: differential responses based on c-Met and FGF19/FGFR4 expression
The FGF/FGFR signaling pathway plays a critical role in human cancers. We analyzed the anti-tumor effect of AZD4547, an inhibitor targeting the FGF/FGFR pathway, in epithelial ovarian cancer (EOC) and strategi... (Source: Cancer Cell International)
Source: Cancer Cell International - January 25, 2024 Category: Cancer & Oncology Authors: Yoo-Young Lee, Ji-Yoon Ryu, Young-Jae Cho, Ju-Yeon Choi, Jung-Joo Choi, Chel Hun Choi, Jason K. Sa, Jae Ryoung Hwang and Jeong-Won Lee Tags: Research Source Type: research
Single-cell N6-methyladenosine-related genes function within the tumor microenvironment to affect the prognosis and treatment sensitivity in patients with gastric cancer
Gastric cancer (GC) ranks fifth for morbidity and third for mortality worldwide. The N6-methyladenosine (m6A) mRNA methylation is crucial in cancer biology and progression. However, the relationship between m6A m... (Source: Cancer Cell International)
Source: Cancer Cell International - January 25, 2024 Category: Cancer & Oncology Authors: Zehua Wang, Chen Chen, Jiao Shu, Jiaoyu Ai, Yihan Liu, Haoyue Cao, Yongxu Jia and Yanru Qin Tags: Research Source Type: research
CircRAD23B promotes proliferation and carboplatin resistance in ovarian cancer cell lines and organoids
Circular RNAs (circRNAs) are involved in the regulation of progression and drug resistance in ovarian cancer (OC). In the present study, we aimed to explore the role of circRAD23B, a newly identified circRNA, ... (Source: Cancer Cell International)
Source: Cancer Cell International - January 25, 2024 Category: Cancer & Oncology Authors: Hui Wang, Yashuang Zhang, Huixian Miao, Ting Xu, Xianglin Nie and Wenjun Cheng Tags: Research Source Type: research
B cells in head and neck squamous cell carcinoma: current opinion and novel therapy
Head and neck squamous cell carcinoma (HNSCC) is a common malignant tumour. Despite advancements in surgery, radiotherapy and chemotherapy, which have improved the prognosis of most patients, a subset of patie... (Source: Cancer Cell International)
Source: Cancer Cell International - January 20, 2024 Category: Cancer & Oncology Authors: Xinyue Guo, Licheng Xu, Luan Nie, Chenyu Zhang, Yaohui Liu, Rui Zhao, Jing Cao, Linli Tian and Ming Liu Tags: Review Source Type: research
