Angiogenesis modulated by CD93 and its natural ligands IGFBP7 and MMRN2: a new target to facilitate solid tumor therapy by vasculature normalization
The tumor vasculature was different from the normal vasculature in both function and morphology, which caused hypoxia in the tumor microenvironment (TME). Previous anti-angiogenesis therapy had led to a modest... (Source: Cancer Cell International)
Source: Cancer Cell International - September 2, 2023 Category: Cancer & Oncology Authors: Yang Li, Lei Fu, Baokang Wu, Xingqi Guo, Yu Shi, Chao Lv, Yang Yu, Yizhou Zhang, Zhiyun Liang, Chongli Zhong, Shukun Han, Feng Xu and Yu Tian Tags: Review Source Type: research
Icariin-Curcumol promotes docetaxel sensitivity in prostate cancer through modulation of the PI3K-Akt signaling pathway and the Warburg effect
This study aimed to determine whether E... (Source: Cancer Cell International)
Source: Cancer Cell International - September 2, 2023 Category: Cancer & Oncology Authors: Wenjing Xu, Jin Ding, Shida Kuang, Bonan Li, Tiansong Sun, Congxu Zhu, Juan Liu, Lemei Zhu, Yingqiu Li and Wen Sheng Tags: Research Source Type: research
MALAT1/ mir-1-3p mediated BRF2 expression promotes HCC progression via inhibiting the LKB1/AMPK signaling pathway
The long non-coding RNA metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) has been reported to play a vital role in the occurrence and development of various tumors. However, the underlying mecha... (Source: Cancer Cell International)
Source: Cancer Cell International - August 31, 2023 Category: Cancer & Oncology Authors: Guang-Zhen Li, Guang-Xiao Meng, Guo-Qiang Pan, Xiao Zhang, Lun-Jie Yan, Rui-Zhe Li, Zi-Niu Ding, Si-Yu Tan, Dong-Xu Wang, Bao-wen Tian, Yu-Chuan Yan, Zhao-Ru Dong, Jian-Guo Hong and Tao Li Tags: Research Source Type: research
Glycolysis-related biomarker TCIRG1 participates in regulation of renal cell carcinoma progression and tumor immune microenvironment by affecting aerobic glycolysis and AKT/mTOR signaling pathway
Renal cell carcinoma (RCC) is a hypermetabolic disease. Abnormal up-regulation of glycolytic signaling promotes tumor growth, and glycolytic metabolism is closely related to immunotherapy of renal cancer. The ... (Source: Cancer Cell International)
Source: Cancer Cell International - August 30, 2023 Category: Cancer & Oncology Authors: Sichen Di, Min Gong, Jianmin Lv, Qiwei Yang, Ye Sun, Yijun Tian, Cheng Qian, Wenjin Chen, Wang Zhou, Keqin Dong, Xiaokai Shi, Yuning Wang, Hongru Wang, Jian Chu, Sishun Gan, Xiuwu Pan & hellip; Tags: Research Source Type: research
Clinical significance of genetic profiling based on different anatomic sites in patients with mucosal melanoma who received or did not receive immune checkpoint inhibitors
In this study, we analyzed genetic alterations according to the primary site of origin, which could provide clues for ... (Source: Cancer Cell International)
Source: Cancer Cell International - August 30, 2023 Category: Cancer & Oncology Authors: Hai-Yun Wang, Ye Liu, Ling Deng, Kuntai Jiang, Xin-Hua Yang, Xiao-Yan Wu, Kai-Hua Guo and Fang Wang Tags: Research Source Type: research
