BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Editorial Board
(Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - September 1, 2023 Category: Neurology Source Type: research

Table of Contents
(Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - September 1, 2023 Category: Neurology Source Type: research

Effective treatment of refractory tinnitus by bilateral deep brain stimulation of the medial geniculate body of the thalamus: A case report
Tinnitus is the perception of a sound in the absence of an audible source. In 1.2% of the population, tinnitus has a large impact on several aspects of daily life and is often accompanied by depression, anxiety and sleep disturbances [1]. Tinnitus is associated with high costs of care, as well as societal and economic burden [2]. Despite the large impact on a person ’s life, treatment options remain limited. Deep brain stimulation (DBS) is considered a promising treatment for refractory tinnitus [3]. (Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - August 31, 2023 Category: Neurology Authors: Jana V.P. Devos, Jasper V. Smit, Erwin L.J. George, Carsten Leue, Linda Ackermans, Yasin Temel, Marcus L.F. Janssen Source Type: research

Tolerability and blinding of high-definition transcranial direct current stimulation among older adults at intensities of up to 4  mA per electrode
Few studies have investigated tolerability, blinding, and double-blinding of High-Definition transcranial Direct Current Stimulation (HD-tDCS) at amplitudes above 2 milliamps (mA). (Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - August 31, 2023 Category: Neurology Authors: Carine El Jamal, Ashley Harrie, Annalise Rahman-Filipiak, Alexandru D. Iordan, Alexandre F. DaSilva, Robert Ploutz-Snyder, Lara Khadr, Michael Vesia, Marom Bikson, Benjamin M. Hampstead Source Type: research

Safety, tolerability and feasibility of remotely-instructed home-based transcranial direct current stimulation in children with cerebral palsy
Perinatal stroke or brain bleeds affect an estimated 1 in 3500 births in the United States, with an increased risk of developing cerebral palsy (CP), a developmental disorder associated with motor impairment [1,2]. While many CP rehabilitation approaches emphasize behavioral repetition to improve gait and upper extremity function, these therapies are costly, restricted to the clinic, and may offer limited functional gains [3]. Therefore, innovative rehabilitation strategies which are accessible, cost-effective, and time-efficient are indicated for long-term benefits. (Source: BRAIN STIMULATION: Basic, Translational, and Cl...
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - August 29, 2023 Category: Neurology Authors: Preston Christopher, Ellen Sutter, Marissa Gavioli, Daniel H. Lench, Gwendolyn Nytes, Veronika Mak, Emma A. Simpson, Chrysanthy Ikonomidou, Melissa A. Villegas, Catarina Saiote, Bernadette T. Gillick Source Type: research

Personalized functional imaging-guided rTMS on the superior frontal gyrus for post-stroke aphasia: A randomized sham-controlled trial
Aphasia affects approximately one-third of stroke patients and yet its rehabilitation outcomes are often unsatisfactory. More effective strategies are needed to promote recovery. (Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - August 29, 2023 Category: Neurology Authors: Jianxun Ren, Weijing Ren, Ying Zhou, Louisa Dahmani, Xinyu Duan, Xiaoxuan Fu, Yezhe Wang, Ruiqi Pan, Jingdu Zhao, Ping Zhang, Bo Wang, Weiyong Yu, Zhenbo Chen, Xin Zhang, Jian Sun, Mengying Ding, Jianting Huang, Liu Xu, Shiyi Li, Weiwei Wang, Wuxiang Xie, Source Type: research

Prefrontal stimulation as a tool to disrupt hippocampal and striatal reactivations underlying fast motor memory consolidation
Recent evidence suggests that hippocampal replay in humans support rapid motor memory consolidation during epochs of wakefulness interleaved with task practice. Objectives/Hypotheses: The goal of this study was to test whether such reactivation patterns can be modulated with experimental interventions and in turn influence fast consolidation. We hypothesized that non-invasive brain stimulation targeting hippocampal and striatal networks via the prefrontal cortex would influence brain reactivation and the rapid form of motor memory consolidation. (Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - August 28, 2023 Category: Neurology Authors: Mareike A. Gann, Nina Dolfen, Bradley R. King, Edwin M. Robertson, Genevi ève Albouy Source Type: research

Centromedian-parafascicular complex deep brain stimulation improves motor symptoms in rapid onset Dystonia ‐Parkinsonism (DYT12-ATP1A3)
Rapid-onset dystonia-parkinsonism, also called DYT12, is a very damaging genetic dystonia, characterized by a rostro-caudal dystonia pattern with prominent bulbar symptoms, sometimes accompanied by parkinsonism symptoms, which has been reported to be caused by aberrant mutations in ATP1A3 [1]. To date, there has been no effective treatment for this disease. Deep-brain stimulation (DBS) has been shown to be an effective treatment option for dystonia; however, in the case of DYT12 dystonia, although some centers have tried different stimulation targets, including the globus pallidus internus (GPi) [2,3], subthalamic nucleus ...
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - August 25, 2023 Category: Neurology Authors: Kai-Liang Wang, Ji-Ping Li, Yong-Zhi Shan, Guo-Guang Zhao, Jing-Hong Ma, Adolfo Ramirez-Zamora, Yu-Qing Zhang Source Type: research

Functional connectomic profile correlates with effective anterior thalamic stimulation for refractory epilepsy
Deep brain stimulation of the anterior nucleus of the thalamus (ANT-DBS) is an effective treatment for refractory epilepsy; however, seizure outcome varies among individuals. Identifying a reliable noninvasive biomarker to predict good responders would be helpful. (Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - August 23, 2023 Category: Neurology Authors: Cuiping Xu, Lei Qi, Xueyuan Wang, Fr édéric L.W.V.J. Schaper, Di Wu, Tao Yu, Xiaoming Yan, Guangyuan Jin, Qiao Wang, Xiaopeng Wang, Xinqi Huang, Yuke Wang, Yuanhong Chen, Jinghui Liu, Yuping Wang, Andreas Horn, Robert S. Fisher, Liankun Ren Source Type: research

Contact dermatitis following an intensive transcranial direct current stimulation protocol for major depressive disorder
In this report, we describe cases of cutaneous side effects in participants who underwent a novel intensive tDCS protocol and developed erythemato-squamous plaques under the anode, consistent with irritative contact dermatitis. (Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - August 22, 2023 Category: Neurology Authors: Jean-Philippe Miron, Maxime Couture, V éronique Desbeaumes Jodoin, Emma Bousseau, Camille Massé-Leblanc, Chantal Bolduc, Daniel M. Blumberger, Abhishek Datta, Michael A. Nitsche, Paul Lespérance Source Type: research

Apathy following deep brain stimulation in Parkinson's disease visualized by 7-Tesla MRI subthalamic network analysis
Apathy is reported after subthalamic nucleus deep brain stimulation (STN DBS) and associated with a decreased quality of life in Parkinson's disease (PD) patients. Recent studies hypothesized that the location of active DBS contact point relative to the STN subdivisions (motor, associative and limbic) could be related to an increase of apathy. (Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - August 21, 2023 Category: Neurology Authors: T.J.C. Zoon, V. Mathiopoulou, G. van Rooijen, van den Munckhof, D.A.J.P. Denys, P.R. Schuurman, R.M.A. de Bie, M. Bot Source Type: research

Feasibility of local field potential-guided programming for deep brain stimulation in Parkinson's disease: A comparison with clinical and neuro-imaging guided approaches in a randomized, controlled pilot trial
Subthalamic nucleus deep brain stimulation (STN-DBS) is an effective treatment for advanced Parkinson's disease (PD). Clinical outcomes after DBS can be limited by poor programming, which remains a clinically driven, lengthy and iterative process. Electrophysiological recordings in PD patients undergoing STN-DBS have shown an association between STN spectral power in the beta frequency band (beta power) and the severity of clinical symptoms. New commercially-available DBS devices now enable the recording of STN beta oscillations in chronically-implanted PD patients, thereby allowing investigation into the use of beta power...
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - August 21, 2023 Category: Neurology Authors: Tobias Binder, Florian Lange, Nicol ò Pozzi, Thomas Mussacchio, Christine Daniels, Thorsten Odorfer, Patrick Fricke, Cordula Matthies, Jens Volkmann, Philipp Capetian Source Type: research

Transcutaneous auricular vagus nerve stimulation (taVNS) decreases heart rate acutely in neonatal rats
Transcutaneous auricular vagus nerve stimulation (taVNS) is an exciting non-invasive extension of traditional invasive cervical VNS. However, it is still unclear what vagus fibers taVNS engages and whether taVNS has measurable effects in reducing heart rate (HR) to assess parasympathetic nervous system activation. Ongoing research and clinical applications pairing VNS with activities promoting learning and stroke recovery are promising [1]. taVNS has also been used in newborns with hypoxic-ischemic (HI) brain injury and may improve their oromotor coordination during feeding [2]. (Source: BRAIN STIMULATION: Basic, Translati...
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - August 21, 2023 Category: Neurology Authors: Melanie W. Gail, Catrina Sims-Robinson, Heather Boger, Adviye Ergul, Rupak Mukherjee, Dorothea D. Jenkins, Mark S. George Source Type: research

Local neuroanatomical and tract-based proxies of optimal subcallosal cingulate deep brain stimulation
Deep brain stimulation of the subcallosal cingulate area (SCC-DBS) is a promising neuromodulatory therapy for treatment-resistant depression (TRD). Biomarkers of optimal target engagement are needed to guide surgical targeting and stimulation parameter selection and to reduce variance in clinical outcome. (Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - August 21, 2023 Category: Neurology Authors: Gavin J.B. Elias, J ürgen Germann, Alexandre Boutet, Michelle E. Beyn, Peter Giacobbe, Ha Neul Song, Ki Sueng Choi, Helen S. Mayberg, Sidney H. Kennedy, Andres M. Lozano Source Type: research

High resolution photon counting CT permits direct visualisation of directional deep brain stimulation lead segments and markers
Directional deep brain stimulation (DBS) leads are a recent addition to the options available for DBS. They are intended to enable current steering towards the intended therapeutic target and away from neighbouring structures, in order to increase stimulation therapeutic window (TW), i.e. the range of amplitudes achieving symptomatic relief without side effects. Some data also suggest lower energy consumption with potential IPG longevity prolongation [1]. (Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - August 21, 2023 Category: Neurology Authors: James Manfield, Sheena Thomas, Charalambous Antoniades, Alexander Green, James Fitzgerald Source Type: research