Local neuroanatomical and tract-based proxies of optimal subcallosal cingulate deep brain stimulation

Deep brain stimulation of the subcallosal cingulate area (SCC-DBS) is a promising neuromodulatory therapy for treatment-resistant depression (TRD). Biomarkers of optimal target engagement are needed to guide surgical targeting and stimulation parameter selection and to reduce variance in clinical outcome.

Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - August 21, 2023 Category: Neurology Authors: Gavin J.B. Elias, J ürgen Germann, Alexandre Boutet, Michelle E. Beyn, Peter Giacobbe, Ha Neul Song, Ki Sueng Choi, Helen S. Mayberg, Sidney H. Kennedy, Andres M. Lozano Source Type: research