BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation RSS feedThis is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Cervical spinal cord stimulation for sleep-disordered breathing in multiple system atrophy
Multiple system atrophy (MSA) is a progressive, debilitating, and fatal neurodegenerative disease with motor and non-motor symptoms. Sleep-disordered breathing (SDB), commonly manifested as obstructive sleep apnea, is frequently observed among MSA patients and is a potential predictor of sudden death [1]. MSA patients present with stridor or snoring, resulting from the dysfunction of brainstem respiratory-associated motor neurons and weakness of the pharynx and larynx muscles, leading to an obstructive breathing pattern [2]. (Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - May 17, 2023 Category: Neurology Authors: Xue Zhu, Sijia Huang, Ning Li, Haiyan Zhou, Ningdi Luo, Fangzheng Chen, Yichi Zhang, Qianyi Yin, Zhengyu Lin, Peng Huang, Linbin Wang, Yuyan Tan, Dianyou Li, Jun Liu Source Type: research

Limited output transcranial electrical stimulation 2023 (LOTES-2023): Updates on engineering principles, regulatory statutes, and industry standards for wellness, over-the-counter, or prescription devices with low risk
The objective and scope of this Limited Output Transcranial Electrical Stimulation 2023 (LOTES-2023) guidance is to update the previous LOTES-2017 guidance. These documents should therefore be considered together. The LOTES provides a clearly articulated and transparent framework for the design of devices providing limited output (specified low-intensity range) transcranial electrical stimulation for a variety of intended uses. These guidelines can inform trial design and regulatory decisions, but most directly inform manufacturer activities - and hence were presented in LOTES-2017 as “Voluntary industry standard for com...
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - May 15, 2023 Category: Neurology Authors: Marom Bikson, Ana Ganho- Ávila, Abhishek Datta, Bernadette Gillick, Morten Goertz Joensson, Sungjin Kim, Jinuk Kim, Adam Kirton, Kiwon Lee, Timothy Marjenin, Balder Onarheim, Erik M. Rehn, Alexander T. Sack, Gozde Unal Source Type: research

Letter to the editor regarding: “Self-administered transcranial direct current stimulation for pain in older adults with knee osteoarthritis: A randomized controlled study”
We read with great interest the recent manuscript published by Martorella et al. [3] entitled “Self-administered transcranial direct current stimulation for pain in older adults with knee osteoarthritis: A randomized controlled study”. The authors investigated the effectiveness of home-based self-administered transcranial direct current stimulation in older adults with knee osteoarthriti s. The importance of this type of study is unquestionable, since knee osteoarthritis covers a considerable part of the worldwide older adult population, and remote transcranial direct current stimulation could facilitate the establishm...
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - May 13, 2023 Category: Neurology Authors: Edson Silva-Filho, Rodrigo Pegado Source Type: research

The timing of transcranial magnetic stimulation relative to the phase of prefrontal alpha EEG modulates downstream target engagement
The communication through coherence model posits that brain rhythms are synchronized across different frequency bands and that effective connectivity strength between interacting regions depends on their phase relation. Evidence to support the model comes mostly from electrophysiological recordings in animals while evidence from human data is limited. (Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - May 13, 2023 Category: Neurology Authors: Spiro P. Pantazatos, James R. Mclntosh, Golbarg T. Saber, Xiaoxiao Sun, Jayce Doose, Josef Faller, Yida Lin, Joshua B. Teves, Aidan Blankenship, Sarah Huffman, Robin I. Goldman, Mark S. George, Paul Sajda, Truman R. Brown Source Type: research

A person with frontotemporal dementia shows increased metabolic rate across multiple brain regions after a series of tDCS sessions
In a previous study [1], we explored the effects of transcranial direct current stimulation (tDCS) on reducing response times in an untrained N-Back task [2]. Our findings indicated that the active tDCS conditions resulted in greater reductions in response times compared to the SHAM condition, with the left-hemisphere targeting montage appearing to be the most effective. These results prompted us to investigate whether this tDCS protocol could elicit measurable neurological changes in the brain. (Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - May 12, 2023 Category: Neurology Authors: C. Roncero, J. Nikelski, J.,P. Soucy, D. Lahiri, B. Seixas-Lima, H. Chertkow Source Type: research

Trigeminal nerve stimulation for prolonged disorders of consciousness: A randomized double-blind sham-controlled study
Trigeminal nerve stimulation (TNS) has been proposed as a promising intervention for coma awakening. However, the effect of TNS on patients with prolonged disorders of consciousness (pDoC) is still unclear. (Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - May 11, 2023 Category: Neurology Authors: Haiyun Ma, Shengnuo Fan, Zhen Xu, Xiaoting Wan, Qian Yang, Yuping Yin, Xuemeng Wu, Shaoling Wu, Hong Zhang, Chao Ma Source Type: research

Letter to the editor: Chronic theta burst stimulation does not significantly modulate glial activity in the healthy non-human primate brain
Repetitive Transcranial Magnetic stimulation (rTMS) is a non-invasive therapeutic tool currently approved by the FDA and Health Canada as an intervention for treatment-resistant depression and is being investigated as an intervention for other neuropsychiatric and neurophysiological disorders [1]. As the clinical applicability of rTMS increases and new protocols are developed, the study of chronic stimulation safety is imperative. (Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - May 8, 2023 Category: Neurology Authors: Lucero Aceves-Serrano, Justin W. Andrushko, Jason L. Neva, Lara A. Boyd, Doris J. Doudet Source Type: research

Neuroethical implications of focused ultrasound for neuropsychiatric illness
MR-guided focused ultrasound is a promising intervention for treatment-resistant mental illness, and merits contextualized ethical exploration in relation to more extensive ethical literature regarding other psychosurgical and neuromodulation treatment options for this patient population. To our knowledge, this topic has not yet been explored in the published literature. (Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - May 5, 2023 Category: Neurology Authors: Rachel Asher, Insoo Hyun, Mitchell Head, G. Rees Cosgrove, David Silbersweig Source Type: research

Serial electroconvulsive Seizure alters dendritic complexity and promotes cellular proliferation in the mouse dentate gyrus; a role for Egr3
Despite being one of the safest, most effective treatments for severe mood disorders, the therapeutic mechanisms of electroconvulsive therapy remain unknown. Electroconvulsive seizure (ECS) induces rapid, high-level expression of immediate early genes (IEGs) and brain-derived neurotrophic factor (BDNF), in addition to stimulation of neurogenesis and dendritic remodeling of dentate gyrus (DG) neurons. We have previously shown that this upregulation of BDNF fails to occur in the hippocampus of mice lacking the IEG Egr3. (Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - May 2, 2023 Category: Neurology Authors: K.T. Meyers, C.C. Damphousse, A.B. Ozols, J.M. Campbell, J.M. Newbern, C. Hu, D.F. Marrone, A.L. Gallitano Source Type: research

Towards optimizing single pulse electrical stimulation: High current intensity, short pulse width stimulation most effectively elicits evoked potentials
While single pulse electrical stimulation (SPES) is increasingly used to study effective connectivity, the effects of varying stimulation parameters on the resulting cortico-cortical evoked potentials (CCEPs) have not been systematically explored. (Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - May 2, 2023 Category: Neurology Authors: Mark A. Hays, Golnoosh Kamali, Mohamad Z. Koubeissi, Sridevi V. Sarma, Nathan E. Crone, Rachel J. Smith, Joon Y. Kang Source Type: research

Cover 1
(Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - May 1, 2023 Category: Neurology Source Type: research

Masthead
(Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - May 1, 2023 Category: Neurology Source Type: research

Editorial Board
(Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - May 1, 2023 Category: Neurology Source Type: research

Table of Contents
(Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - May 1, 2023 Category: Neurology Source Type: research

How I became myself after merging with a computer: Does human-machine symbiosis raise human rights issues?
Novel usages of brain stimulation combined with artificially intelligent (AI) systems promise to address a large range of diseases. These new conjoined technologies, such as brain-computer interfaces (BCI), are increasingly used in experimental and clinical settings to predict and alleviate symptoms of various neurological and psychiatric disorders. Due to their reliance on AI algorithms for feature extraction and classification, these BCI systems enable a novel, unprecedented, and direct connection between human cognition and artificial information processing. (Source: BRAIN STIMULATION: Basic, Translational, and Clinical...
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - May 1, 2023 Category: Neurology Authors: Frederic Gilbert, Marcello Ienca, Mark Cook Source Type: research