Editorial Board
(Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - November 1, 2023 Category: Neurology Source Type: research

Table of Contents
(Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - November 1, 2023 Category: Neurology Source Type: research

Effects of multisession cathodal transcranial direct current stimulation with cognitive training on sociocognitive functioning and brain dynamics in ASD: A double-blind, sham-controlled, randomized EEG study
Few treatment options are available for targeting core symptoms of autism spectrum disorder (ASD). The development of treatments that target common neural circuit dysfunctions caused by known genetic defects, namely, disruption of the excitation/inhibition (E/I) balance, is promising. Transcranial direct current stimulation (tDCS) is capable of modulating the E/I balance in healthy individuals, yet its clinical and neurobiological effects in ASD remain elusive. (Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - October 31, 2023 Category: Neurology Authors: Melody M.Y. Chan, Coco X.T. Choi, Tom C.W. Tsoi, Caroline K.S. Shea, Klaire W.K. Yiu, Yvonne M.Y. Han Source Type: research

The effects of STN-DBS on motor speech: A longitudinal articulographic study
Speech deficits in Parkinson's disease (PD) manifest as hypokinetic dysarthria comprising reduced ability to modulate speech melody and loudness, and imprecise articulation [1]. The latter results from smaller, slower, and less precise articulatory movements further leading to reduced intelligibility [1]. The effect of deep brain stimulation of the subthalamic nucleus (STN-DBS) on speech is under debate. Whereas some studies report improvement, e.g. Refs. [2 –4], others report a deterioration of speech functions, e.g. (Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - October 28, 2023 Category: Neurology Authors: Tabea Thies, Hannah Jergas, Doris M ücke, Gregor Brandt, Veerle Visser-Vandewalle, Serge Pinto, Michael T. Barbe Source Type: research

Toward a neurocircuit-based sequential bilateral transcranial magnetic stimulation for treatment of obsessive-compulsive disorder
Individuals diagnosed with obsessive-compulsive disorder (OCD) present a substantial demand for innovative therapeutic interventions, given that they often endure significant residual symptoms despite undergoing treatment [1]. The prevailing body of research has predominantly explored the utility of repetitive transcranial magnetic stimulation (rTMS) as a non-invasive cerebral stimulation technique for alternative interventions. High frequency rTMS (HF-rTMS; ≥5 Hz) can produce a local increase in cortical excitability, whereas low frequency rTMS (LF-rTMS; ≤1 Hz) can produce decreases in local cortical excitability [2]....
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - October 27, 2023 Category: Neurology Authors: Kun Wei, Yange Luo, Yuyin Bai, Titi Chen, Bo Bi Source Type: research

A novel free-moving rat model of transcranial direct current stimulation
Despite the popularity of transcranial direct current stimulation (tDCS), we still do not know how this neuromodulation method exerts many of its effects. Animal models of tDCS are used to emulate human tDCS with the aim of investigating the technique's effects and obtaining mechanistic insights. The most frequently used animal in tDCS research is the rat [1]. An influential article from V öröslakos described a novel method of true transcranial stimulation through the scalp in the anesthetized rat, using a pair of silicon single-pocket electrodes filled with conductive EEG gel [2]. (Source: BRAIN STIMULATION: Basic, Tran...
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - October 27, 2023 Category: Neurology Authors: Luuk van Boekholdt, Silke Kerstens, Kaydee Decloedt, Myles Mc Laughlin Source Type: research

Pretreatment pupillary reactivity is associated with differential early response to 10 Hz and intermittent theta-burst repetitive transcranial magnetic stimulation (rTMS) treatment of major depressive disorder (MDD)
Repetitive Transcranial Magnetic Stimulation (rTMS) is an effective treatment for Major Depressive Disorder (MDD). Two common rTMS protocols, 10 Hz and intermittent theta burst stimulation (iTBS), have comparable rates of efficacy in groups of patients. Recent evidence suggests that some individuals may be more likely to benefit from one form of stimulation than the other. The pretreatment pupillary light reflex (PLR) is significantly associated with response to a full course of rTMS using heterogeneous stimulation protocols. (Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - October 18, 2023 Category: Neurology Authors: Cole Citrenbaum, Juliana Corlier, Doan Ngo, Nikita Vince-Cruz, Andrew Wilson, Scott A. Wilke, David Krantz, Reza Tadayonnejad, Nathaniel Ginder, Jennifer Levitt, John H. Lee, Michael K. Leuchter, Thomas B. Strouse, Andrew Corse, Pooja Vyas, Andrew F. Leuc Source Type: research

Temporally non-regular patterns of deep brain stimulation (DBS) enhance assessment of evoked potentials while maintaining motor symptom management in Parkinson's disease (PD)
Traditional deep brain stimulation (DBS) at fixed regular frequencies (>100  Hz) is effective in treating motor symptoms of Parkinson's disease (PD). Temporally non-regular patterns of DBS are a new parameter space that may help increase efficacy and efficiency. (Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - October 18, 2023 Category: Neurology Authors: Kay Palopoli-Trojani, Stephen L. Schmidt, Karley D. Baringer, Theodore A. Slotkin, Jennifer J. Peters, Dennis A. Turner, Warren M. Grill Source Type: research

1Hz right orbitofrontal TMS benefits depressed patients unresponsive to dorsolateral prefrontal cortex TMS
Major depressive disorder (MDD) remains a significant global health challenge. Patients failing to achieve remission despite multiple conventional therapeutic interventions (i.e., difficult-to-treat or treatment-resistant depression, TRD) constitute nearly 30  % of MDD cases [1]. Repetitive transcranial magnetic stimulation (TMS) has gained traction as a promising non-invasive approach in TRD, conventionally targeting the dorsolateral prefrontal cortex (DLPFC) [2]. While high-frequency TMS applied to the left DLPFC has demonstrated remission rates rang ing from 19 % to 37 % [3,4] but augmented 1Hz-R-DLPFC results in ...
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - October 13, 2023 Category: Neurology Authors: Amourie Prentice, Ylka Kolken, Christina Tuttle, Joris van Neijenhof, Richard Pitch, Iris van Oostrom, Vera Kruiver, Jonathan Downar, Alexander T. Sack, Martijn Arns, Nikita van der Vinne Source Type: research

Meniere Disease treated with transcutaneous auricular vagus nerve stimulation combined with betahistine Mesylate: A randomized controlled trial
Meniere Disease is a clinical condition defined by hearing loss, tinnitus, and aural fullness symptoms, there are currently no any medications approved for its treatment. (Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - October 12, 2023 Category: Neurology Authors: Dong Wu, Bo Liu, Yunqing Wu, Yu Wang, Jingyi Sun, Jun Yang, Jinping Duan, Gang Liu, Kai Cao, Yi Zhang, Peijing Rong Source Type: research

Dosing transcranial magnetic stimulation in major depressive disorder: Relations between number of treatment sessions and effectiveness in a large patient registry
The number of sessions in an acute TMS course for major depressive disorder (MDD) is greater than in the earlier randomized controlled trials. (Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - October 10, 2023 Category: Neurology Authors: Todd M. Hutton, Scott T. Aaronson, Linda L. Carpenter, Kenneth Pages, David Krantz, Lindsay Lucas, Bing Chen, Harold A. Sackeim Source Type: research

Causal influence of brainstem response to transcutaneous vagus nerve stimulation on cardiovagal outflow
The autonomic response to transcutaneous auricular vagus nerve stimulation (taVNS) has been linked to the engagement of brainstem circuitry modulating autonomic outflow. However, the physiological mechanisms supporting such efferent vagal responses are not well understood, particularly in humans. (Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - October 10, 2023 Category: Neurology Authors: Nicola Toschi, Andrea Duggento, Riccardo Barbieri, Ronald G. Garcia, Harrison P. Fisher, Norman W. Kettner, Vitaly Napadow, Roberta Sclocco Source Type: research

TMS of parietal and occipital cortex locked to spontaneous transient large-scale brain states enhances natural oscillations in EEG
Fluctuating neuronal network states influence brain responses to transcranial magnetic stimulation (TMS). Our previous studies revealed that transient spontaneous bihemispheric brain states in the EEG, driven by oscillatory power, information flow and regional domination, modify cortical EEG responses to TMS. However, the impact of ongoing fluctuations of large-scale brain network states on TMS-EEG responses has not been explored. (Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - October 10, 2023 Category: Neurology Authors: Yang Bai, Jie Xuan, Shihang Jia, Ulf Ziemann Source Type: research

Efficacy of insula deep repetitive transcranial magnetic stimulation combined with varenicline for smoking cessation: A randomized, double-blind, sham controlled trial
Current smoking cessation treatments are limited in terms of efficacy, particularly with regards to long term abstinence. There is a large amount of evidence implicating the insula in nicotine addiction. (Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - October 6, 2023 Category: Neurology Authors: Christine Ibrahim, Victor M. Tang, Daniel M. Blumberger, Saima Malik, Rachel Tyndale, Allison Trevizol, Mera S. Barr, Zafiris J. Daskalakis, Abraham Zangen, Bernard Le Foll Source Type: research

Corrigendum to “Characterization of vagus nerve stimulation-induced pupillary responses in epileptic patients” [Brain Stimul. 15 (2022) 1498–1507]
The authors of the above paper would like to point out an omission in the ‘Funding Sources’ section of their paper. The sentence, ”and by the Queen Elisabeth Medical Foundation for Neurosciences (F.M.R.E.-G.S.K.E.), which is a Belgian non-profit organization that support clinical research in the field of neurosciences (https://www.fmre-gske.be/pages/en/actual.html)” was mistakenly omitted from the end of this section. (Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - October 2, 2023 Category: Neurology Authors: Simone Vespa, Lars Stumpp, Giulia Liberati, Jean Delbeke, Antoine Nonclercq, Andr é Mouraux, Riëm El Tahry Source Type: research