High-intensity interval training induces lactylation of fatty acid synthase to inhibit lipid synthesis
The aim of study was to observe the effect of increased lactate levels during high-intensity interval training (HIIT) on protein lactylation, identify the target protein, and investigate the regulatory effect ... (Source: BMC Biology)
Source: BMC Biology - September 19, 2023 Category: Biology Authors: Xuefei Chen, Wenhua Huang, Jingbo Zhang, Yanjun Li, Zheng Xing, Lanlan Guo, Hongfeng Jiang and Jing Zhang Tags: Research article Source Type: research
The dynamics of deltamethrin resistance evolution in Aedes albopictus has an impact on fitness and dengue virus type-2 vectorial capacity
Worldwide invasion and expansion of Aedes albopictus, an important vector of dengue, chikungunya, and Zika viruses, has become a serious concern in global public health. Chemical insecticides are the primary mean... (Source: BMC Biology)
Source: BMC Biology - September 13, 2023 Category: Biology Authors: Yijia Guo, Ke Hu, Jingni Zhou, Zhensheng Xie, Yijie Zhao, Siyu Zhao, Jinbao Gu, Xiaohong Zhou, Guiyun Yan, Anthony A. James and Xiao-Guang Chen Tags: Research article Source Type: research
Quantitative determination of fluorescence labeling implemented in cell cultures
Labeling efficiency is a crucial parameter in fluorescence applications, especially when studying biomolecular interactions. Current approaches for estimating the yield of fluorescent labeling have critical dr... (Source: BMC Biology)
Source: BMC Biology - September 12, 2023 Category: Biology Authors: Chiara Schirripa Spagnolo, Aldo Moscardini, Rosy Amodeo, Fabio Beltram and Stefano Luin Tags: Methodology article Source Type: research
Diversity of RNA viruses in the cosmopolitan monoxenous trypanosomatid Leptomonas pyrrhocoris
Trypanosomatids are parasitic flagellates well known because of some representatives infecting humans, domestic animals, and cultural plants. Many trypanosomatid species bear RNA viruses, which, in the case of... (Source: BMC Biology)
Source: BMC Biology - September 12, 2023 Category: Biology Authors: Diego H. Macedo, Danyil Grybchuk, Jana Re žnarová, Jan Votýpka, Donnamae Klocek, Tatiana Yurchenko, Jan Ševčík, Alice Magri, Michaela Urda Dolinská, Kristína Záhonová, Julius Lukeš, Elena Servienė, Alexandra Jászayová, Saulius Serva, Marina Tags: Research article Source Type: research
Genome and whole-genome resequencing of Cinnamomum camphora elucidate its dominance in subtropical urban landscapes
Lauraceae is well known for its significant phylogenetic position as well as important economic and ornamental value; however, most evergreen species in Lauraceae are restricted to tropical regions. In contras... (Source: BMC Biology)
Source: BMC Biology - September 12, 2023 Category: Biology Authors: Danqing Li, Han-Yang Lin, Xiuyun Wang, Bo Bi, Yuan Gao, Lingmei Shao, Runlong Zhang, Yuwei Liang, Yiping Xia, Yun-Peng Zhao, Xiaofan Zhou and Liangsheng Zhang Tags: Research article Source Type: research
Prefoldin 2 contributes to mitochondrial morphology and function
Prefoldin is an evolutionarily conserved co-chaperone of the tailless complex polypeptide 1 ring complex (TRiC)/chaperonin containing tailless complex 1 (CCT). The prefoldin complex consists of six subunits th... (Source: BMC Biology)
Source: BMC Biology - September 12, 2023 Category: Biology Authors: Ismail Tahmaz, Somayeh Shahmoradi Ghahe, Monika Stasiak, Kamila P. Liput, Katarzyna Jonak and Ulrike Topf Tags: Research article Source Type: research
Protein intrinsically disordered region prediction by combining neural architecture search and multi-objective genetic algorithm
Intrinsically disordered regions (IDRs) are widely distributed in proteins and related to many important biological functions. Accurately identifying IDRs is of great significance for protein structure and fun... (Source: BMC Biology)
Source: BMC Biology - September 7, 2023 Category: Biology Authors: Yi-Jun Tang, Ke Yan, Xingyi Zhang, Ye Tian and Bin Liu Tags: Methodology article Source Type: research
The Automated Systematic Search Deduplicator (ASySD): a rapid, open-source, interoperable tool to remove duplicate citations in biomedical systematic reviews
Researchers performing high-quality systematic reviews search across multiple databases to identify relevant evidence. However, the same publication is often retrieved from several databases. Identifying and r... (Source: BMC Biology)
Source: BMC Biology - September 7, 2023 Category: Biology Authors: Kaitlyn Hair, Zsanett Bahor, Malcolm Macleod, Jing Liao and Emily S. Sena Tags: Methodology article Source Type: research
Increased paternal corticosterone exposure influences offspring behaviour and expression of urinary pheromones
Studies have shown that paternal stress prior to conception can influence the innate behaviours of their offspring. The evolutionary impacts of such intergenerational effects are therefore of considerable inte... (Source: BMC Biology)
Source: BMC Biology - September 5, 2023 Category: Biology Authors: Lucas B. Hoffmann, Evangeline A. McVicar, Rebekah V. Harris, Coralina Collar-Fern ández, Michael B. Clark, Anthony J. Hannan and Terence Y. Pang Tags: Research article Source Type: research
Cuticular competing endogenous RNAs regulate insecticide penetration and resistance in a major agricultural pest
The continuously developing pesticide resistance is a great threat to agriculture and human health. Understanding the mechanisms of insecticide resistance is a key step in dealing with the phenomenon. Insect c... (Source: BMC Biology)
Source: BMC Biology - September 5, 2023 Category: Biology Authors: Li-Wei Meng, Guo-Rui Yuan, Meng-Ling Chen, Li-Sha Zheng, Wei Dou, Yu Peng, Wen-Jie Bai, Zhen-Yu Li, John Vontas and Jin-Jun Wang Tags: Research article Source Type: research
Beyond rational —biosensor-guided isolation of 100 independently evolved bacterial strain variants and comparative analysis of their genomes
In contrast to modern rational metabolic engineering, classical strain development strongly relies on random mutagenesis and screening for the desired production phenotype. Nowadays, with the availability of b... (Source: BMC Biology)
Source: BMC Biology - September 4, 2023 Category: Biology Authors: Philipp T. Baumann, Michael Dal Molin, Hannah Aring, Karin Krumbach, Moritz-Fabian M üller, Bas Vroling, Philana V. van Summeren-Wesenhagen, Stephan Noack and Jan Marienhagen Tags: Research article Source Type: research
Personalised modelling of clinical heterogeneity between medium-chain acyl-CoA dehydrogenase patients
Monogenetic inborn errors of metabolism cause a wide phenotypic heterogeneity that may even differ between family members carrying the same genetic variant. Computational modelling of metabolic networks may id... (Source: BMC Biology)
Source: BMC Biology - September 4, 2023 Category: Biology Authors: Christoff Odendaal, Emmalie A. Jager, Anne-Claire M. F. Martines, Marcel A. Vieira-Lara, Nicolette C. A. Huijkman, Ligia A. Kiyuna, Albert Gerding, Justina C. Wolters, Rebecca Heiner-Fokkema, Karen van Eunen, Terry G. J. Derks and Barbara M. Bakker Tags: Research article Source Type: research
Spatial biology of Ising-like synthetic genetic networks
Understanding how spatial patterns of gene expression emerge from the interaction of individual gene networks is a fundamental challenge in biology. Developing a synthetic experimental system with a common the... (Source: BMC Biology)
Source: BMC Biology - September 4, 2023 Category: Biology Authors: Kevin Simpson, Alfredo L ’Homme, Juan Keymer and Fernán Federici Tags: Research article Source Type: research
Whole-genome sequencing reveals adaptations of hairy-footed jerboas (Dipus, Dipodidae) to diverse desert environments
Environmental conditions vary among deserts across the world, spanning from hyper-arid to high-elevation deserts. However, prior genomic studies on desert adaptation have focused on desert and non-desert compa... (Source: BMC Biology)
Source: BMC Biology - August 30, 2023 Category: Biology Authors: Xingwen Peng, Jilong Cheng, Hong Li, Anderson Feij ó, Lin Xia, Deyan Ge, Zhixin Wen and Qisen Yang Tags: Research article Source Type: research
Differential functions of RhoGDI β in malignant transformation and progression of urothelial cell following N-butyl-N-(4-hydmoxybutyl) nitrosamine exposure
Functional role of Rho GDP-dissociation inhibitor beta (RhoGDI β) in tumor biology appears to be contradictory across various studies. Thus, the exploration of the molecular mechanisms underlying the differenti... (Source: BMC Biology)
Source: BMC Biology - August 28, 2023 Category: Biology Authors: Xiaohui Hua, Ronghao Zou, Xiaoyue Bai, Yuyao Yang, Juan Lu and Chuanshu Huang Tags: Research article Source Type: research
