Personalised modelling of clinical heterogeneity between medium-chain acyl-CoA dehydrogenase patients

Monogenetic inborn errors of metabolism cause a wide phenotypic heterogeneity that may even differ between family members carrying the same genetic variant. Computational modelling of metabolic networks may id...

Source: BMC Biology - September 4, 2023 Category: Biology Authors: Christoff Odendaal, Emmalie A. Jager, Anne-Claire M. F. Martines, Marcel A. Vieira-Lara, Nicolette C. A. Huijkman, Ligia A. Kiyuna, Albert Gerding, Justina C. Wolters, Rebecca Heiner-Fokkema, Karen van Eunen, Terry G. J. Derks and Barbara M. Bakker Tags: Research article Source Type: research