Single-cell and spatial transcriptomics reveal changes in cell heterogeneity during progression of human tendinopathy
Musculoskeletal tissue degeneration impairs the life quality and motor function of many people, especially seniors and athletes. Tendinopathy is one of the most common diseases associated with musculoskeletal ... (Source: BMC Biology)
Source: BMC Biology - June 6, 2023 Category: Biology Authors: Weili Fu, Runze Yang and Jian Li Tags: Research article Source Type: research
The genomes of Vischeria oleaginous microalgae shed light on the molecular basis of hyper-accumulation of lipids
With the urgent need to reduce carbon emissions, and the dwindling reserves of easily exploitable fossil fuel, microalgae-based biofuels that can be used for transport systems and CO2 abatement have attracted gre... (Source: BMC Biology)
Source: BMC Biology - June 6, 2023 Category: Biology Authors: Baoyan Gao, Meng Xu, Dai Shan, Chi Zhang, Yulan Yang, Zhensheng Dong, Hu Zhang, Boping Han, Luodong Huang and Chengwu Zhang Tags: Research article Source Type: research
The Sapria himalayana genome provides new insights into the lifestyle of endoparasitic plants
Sapria himalayana (Rafflesiaceae) is an endoparasitic plant characterized by a greatly reduced vegetative body and giant flowers; however, the mechanisms underlying its special lifestyle and greatly altered plant... (Source: BMC Biology)
Source: BMC Biology - June 6, 2023 Category: Biology Authors: Xuelian Guo, Xiaodi Hu, Jianwu Li, Bingyi Shao, Yajun Wang, Long Wang, Kui Li, Dongliang Lin, Hanchen Wang, Zhiyuan Gao, Yuannian Jiao, Yingying Wen, Hongyu Ji, Chongbo Ma, Song Ge, Wenkai Jiang & hellip; Tags: Research article Source Type: research
Snakes on a plain: biotic and abiotic factors determine venom compositional variation in a wide-ranging generalist rattlesnake
Snake venoms are trophic adaptations that represent an ideal model to examine the evolutionary factors that shape polymorphic traits under strong natural selection. Venom compositional variation is substantial... (Source: BMC Biology)
Source: BMC Biology - June 6, 2023 Category: Biology Authors: Cara F. Smith, Zachary L. Nikolakis, Kathleen Ivey, Blair W. Perry, Drew R. Schield, Neil R. Balchan, Joshua Parker, Kirk C. Hansen, Anthony J. Saviola, Todd A. Castoe and Stephen P. Mackessy Tags: Research article Source Type: research
Omission responses in local field potentials in rat auditory cortex
Non-invasive recordings of gross neural activity in humans often show responses to omitted stimuli in steady trains of identical stimuli. This has been taken as evidence for the neural coding of prediction or ... (Source: BMC Biology)
Source: BMC Biology - May 30, 2023 Category: Biology Authors: Ryszard Auksztulewicz, Vani Gurusamy Rajendran, Fei Peng, Jan Wilbert Hendrik Schnupp and Nicol Spencer Harper Tags: Research article Source Type: research
Author Correction: Unique sperm haplotypes are associated with phenotypically different sperm subpopulations in Astyanax fish
(Source: BMC Biology)
Source: BMC Biology - May 29, 2023 Category: Biology Authors: Richard Borowsky, Alissa Luk, Xinjian He and Rebecca S. Kim Tags: Correction Source Type: research
Range-wide population genomics of common seadragons shows secondary contact over a former barrier and insights on illegal capture
Common seadragons (Phyllopteryx taeniolatus, Syngnathidae) are an emblem of the diverse endemic fauna of Australia ’s southern rocky reefs, the newly recognized “Great Southern Reef.” A lack of assessments spannin... (Source: BMC Biology)
Source: BMC Biology - May 29, 2023 Category: Biology Authors: Josefin Stiller, Nerida G. Wilson and Greg W. Rouse Tags: Research article Source Type: research
Circular RNAs arising from synaptic host genes during human neuronal differentiation are modulated by SFPQ RNA-binding protein
Circular RNA (circRNA) molecules, generated through non-canonical back-splicing of exon-exon junctions, have recently been implicated in diverse biological functions including transcriptional regulation and mo... (Source: BMC Biology)
Source: BMC Biology - May 26, 2023 Category: Biology Authors: Michelle E. Watts, Marika Oksanen, Sanna Lejerkrans, Francesca Mastropasqua, Myriam Gorospe and Kristiina Tammimies Tags: Research article Source Type: research
A unique effector secreted by Pseudozyma flocculosa mediates its biocontrol activity
Pseudozyma flocculosa is a highly efficient biocontrol agent (BCA) of powdery mildews whose mode of action remains elusive. It is known to secrete unique effectors during its interaction with powdery mildews but ... (Source: BMC Biology)
Source: BMC Biology - May 24, 2023 Category: Biology Authors: Parthasarathy Santhanam, Mst Hur Madina, Fernanda Matias Albuini, Caroline Labb é, Luciano Gomes Fietto and Richard R. Bélanger Tags: Research article Source Type: research
Genomic, functional and structural analyses elucidate evolutionary innovation within the sea anemone 8 toxin family
The ShK toxin from Stichodactyla helianthus has established the therapeutic potential of sea anemone venom peptides, but many lineage-specific toxin families in Actiniarians remain uncharacterised. One such pepti... (Source: BMC Biology)
Source: BMC Biology - May 24, 2023 Category: Biology Authors: Lauren M. Ashwood, Khaled A. Elnahriry, Zachary K. Stewart, Thomas Shafee, Muhammad Umair Naseem, Tibor G. Szanto, Chlo é A. van der Burg, Hayden L. Smith, Joachim M. Surm, Eivind A. B. Undheim, Bruno Madio, Brett R. Hamilton, Shaodong Guo, Dorothy C. C. Tags: Research article Source Type: research
Epigenetic regulation of human-specific gene expression in the prefrontal cortex
Changes in gene expression levels during brain development are thought to have played an important role in the evolution of human cognition. With the advent of high-throughput sequencing technologies, changes ... (Source: BMC Biology)
Source: BMC Biology - May 24, 2023 Category: Biology Authors: Weifen Sun, Gangcai Xie, Xi Jiang, Philipp Khaitovich, Dingding Han and Xiling Liu Tags: Research article Source Type: research
CCP5 and CCP6 retain CP110 and negatively regulate ciliogenesis
The axonemal microtubules of primary cilium undergo a conserved protein posttranslational modification (PTM) — polyglutamylation. This reversible procedure is processed by tubulin tyrosine ligase-like polyglut... (Source: BMC Biology)
Source: BMC Biology - May 24, 2023 Category: Biology Authors: Yujuan Wang, Yuan Zhang, Xinyu Guo, Yiqiang Zheng, Xinjie Zhang, Shanshan Feng and Hui-Yuan Wu Tags: Research article Source Type: research
Molecular drivers of insecticide resistance in the Sahelo-Sudanian populations of a major malaria vector Anopheles coluzzii
Information on common markers of metabolic resistance in malaria vectors from countries sharing similar eco-climatic characteristics can facilitate coordination of malaria control. Here, we characterized popul... (Source: BMC Biology)
Source: BMC Biology - May 24, 2023 Category: Biology Authors: Sulaiman S. Ibrahim, Abdullahi Muhammad, Jack Hearn, Gareth D. Weedall, Sanjay C. Nagi, Muhammad M. Mukhtar, Amen N. Fadel, Leon J. Mugenzi, Edward I. Patterson, Helen Irving and Charles S. Wondji Tags: Research article Source Type: research
Next steps after airing disagreement on a scientific issue with policy implications: a meta-analysis, multi-lab replication and adversarial collaboration
Canadian policymakers are interested in determining whether farmed Atlantic salmon, frequently infected with Piscine orthoreovirus (PRV), may threaten wild salmon populations in the Pacific Northwest. A relevant ... (Source: BMC Biology)
Source: BMC Biology - May 23, 2023 Category: Biology Authors: Shinichi Nakagawa and Malgorzata Lagisz Tags: Commentary Source Type: research
Author Correction: Innate antiviral defense demonstrates high energetic efficiency in a bony fish
(Source: BMC Biology)
Source: BMC Biology - May 19, 2023 Category: Biology Authors: Mark P. Polinski, Yangfan Zhang, Phillip R. Morrison, Gary D. Marty, Colin J. Brauner, Anthony P. Farrell and Kyle A. Garver Tags: Correction Source Type: research
